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Sipkin A.M.

Moscow Regional Research and Clinical Institute

Misikov V.K.

Moscow Regional Research and Clinical Institute named after M.F. Vladimirskii

Utiashvili N.I.

Moscow Regional Research and Clinical Institute named after M.F. Vladimirskii

Injection of incobotulinum toxin A for the prevention of postoperative salivary fistula and sialocele

Authors:

Sipkin A.M., Misikov V.K., Utiashvili N.I.

More about the authors

Journal: Stomatology. 2021;100(2): 55‑59

DOI: 10.17116/stomat202110002155

Read: 2422 times

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Table of contents

INJECTION OF INCOBOTULINUM TOXIN A FOR THE PREVENTION OF POSTOPERATIVE SALIVARY FISTULA AND SIALOCELE
INJECTION OF INCOBOTULINUM TOXIN A FOR THE PREVENTION OF POSTOPERATIVE SALIVARY FISTULA AND SIALOCELE

To cite this article:

Sipkin AM, Misikov VK, Utiashvili NI. Injection of incobotulinum toxin A for the prevention of postoperative salivary fistula and sialocele. Stomatology. 2021;100(2):55‑59. (In Russ.)
https://doi.org/10.17116/stomat202110002155

 
Подписка 2026 Стоматология (Stomatology)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The aim of the clinical study was to improve prevention of postoperative sialocele and fistulas of parotid glands.

MATERIALS AND METHODS

The study included 100 patients with tumors of parotid glands treated by superficial parotidecthomy. Fifty patients received incobotulinum toxin A preoperatively, while control group consisted of 50 patients without preoperative injections.

RESULTS

Salivary fistulas formed in 17% of cases in control group. Discharging of saliva through the postoperative wound for 6 days after surgical treatment were noticed in the control group in 30% of cases. There were no complications such as forming of salivary fistula and sialocele and no saliva flow from the postoperative wound on the 4th day after surgical treatment in the main group. Conclusion. The use of botulinum toxin type A proved an efficient and effective way for prevention of postoperative salivary fistulas and sialocele.

Keywords:

salivary gland
salivary fistula
sialocele
tumor of parotid gland
botulinum toxin type A

Authors:

Sipkin A.M.

Moscow Regional Research and Clinical Institute

Misikov V.K.

Moscow Regional Research and Clinical Institute named after M.F. Vladimirskii

Utiashvili N.I.

Moscow Regional Research and Clinical Institute named after M.F. Vladimirskii

Received:

16.09.2020

Accepted:

16.11.2020

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References:

  1. Afanasiev VV. Slyunnye zhelezy. Bolezni i travmy. Rukovodstvo dlya vrachei. GEOTAR-media; 2012. (In Russ.).
  2. Tymofieiev AA, Kindras IB, Maksymcha SV, Kryvosheieva AI. Features of clinical flow and treatment of patients with the pleomorphic adenoma of parotid glands. Sovremennaya stomatologiya. 2013;3:80-85. (In Russ.).
  3. Witt RL. The incidence and management of siaolocele after parotidectomy. Otolaryngol Head Neck Surg. 2009;140(6):871-874. PMID: 19467406. https://doi.org/10.1016/j.otohns.2009.01.021
  4. Afanasiev VV, Dubov DV. A new method for the surgical treatment of complete external salivary fistula of the parotid duct. Rossiiskaya stomatologiya. 2013;6:3:7-9. (In Russ.).
  5. Melville JC, Stackowicz DJ, Jundt JS, Shum JW. Use of Botox (OnabotulinumtoxinA) for the Treatment of Parotid Sialocele and Fistula After Extirpation of Buccal Squamous Cell Carcinoma With Immediate Reconstruction Using Microvascular Free Flap: A Report of 3 Cases. J Oral Maxillofac Surg. 2016;74(8):1678-1686. Epub 2016 Jan 29. PMID: 26902710. https://doi.org/10.1016/j.joms.2016.01.038
  6. Rana K, Rathore PK, Raj A, Meher R, Wadhwa V, Prakash A, Rajan S. Bilateral spontaneous salivary otorrhoea: Case report and a review of the literature. Int J Pediatr Otorhinolaryngol. 2015;79(10):1774-1777. Epub 2015 Jul 31. PMID: 26260660. https://doi.org/10.1016/j.ijporl.2015.07.032
  7. Dorofeev AL. eBotulin therapy in a clinical practice. Mezhdunarodnyi zhurnal prikladnykh i fundamental’nykh issledovanii. 2017;2-2:179-184. (In Russ.).
  8. Krasavina DA. Botulinotoxin treatment of patients with facial paralysis. RMZH. 2017;25:24:1767-1770. (In Russ.).
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