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Savicheva A.M.

NII akusherstva i ginekologii im. D.O. Otta RAMN, Sankt-Peterburg

Rybina E.V.

Nauchno-issledovatel'skiĭ institut akusherstva i ginekologii im. D.O. Otta RAMN, Sankt-Peterburg

In vitro evaluation of the effect of polygynax on the microorganisms isolatedfrom the female vagina

Authors:

Savicheva A.M., Rybina E.V.

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Journal: Russian Bulletin of Obstetrician-Gynecologist. 2012;12(4): 104‑107

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IN VITRO EVALUATION OF THE EFFECT OF POLYGYNAX ON THE MICROORGANISMS ISOLATEDFROM THE FEMALE VAGINA
IN VITRO EVALUATION OF THE EFFECT OF POLYGYNAX ON THE MICROORGANISMS ISOLATEDFROM THE FEMALE VAGINA

To cite this article:

Savicheva AM, Rybina EV. In vitro evaluation of the effect of polygynax on the microorganisms isolatedfrom the female vagina. Russian Bulletin of Obstetrician-Gynecologist. 2012;12(4):104‑107. (In Russ.)

 
Подписка 2025-2 (Russian Bulletin of Obstetrician-Gynecologist)
 
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The effect of polygynax on 24-hour cultures of 163 strains of the microorganisms isolated from the vagina of reproductive-aged women was evaluated in an in vitro experiment. The concentrated solution of polygynax and its dilutions in isotonic sodium chloride solution were tested. Gram-negative bacteria were found to be highly susceptible to the antibacterial agents contained in polygynax. Yeast-like fungi of the genus Candida were susceptible to nystatin that is a component of polygynax. The lactobacilli isolated from the vagina of reproductive-aged women were resistant to polygynax even at the lowest concentration.

Keywords:

vulvovaginitis
cultures of microorganisms isolated from the female vagina
polygynax

Authors:

Savicheva A.M.

NII akusherstva i ginekologii im. D.O. Otta RAMN, Sankt-Peterburg

Rybina E.V.

Nauchno-issledovatel'skiĭ institut akusherstva i ginekologii im. D.O. Otta RAMN, Sankt-Peterburg

List of references:

  1. Savicheva A.M., Sokolovskii E.V., Domeika M. Kratkoe rukovodstvo po mikroskopicheskoi diagnostike infektsii, peredavaemykh polovym putem. SPb: Foliant 2004; 128.
  2. Fan A.P., Xue F.X. Clinical characteristics of aerobic vaginitis and its mixed infections. Zhonghua Fu Chan Ke Za Zhi 2010; 45: 12: 904-908.
  3. Frey Tirri B. Antimicrobial topical agents used in the vagina. Curr Probl Dermatol 2011; 40: 36-47.
  4. Goran D., Vesna A., Adela S., Biljana T.K., Snezana M. Polygynax in the treatment of fungal and non specific vaginitis. Akush Ginekol (Sofiia) 2004; 43: 6: 23-26.
  5. Nolewajka-Lasak I., Rajca M., Kamiński K., Kunicka M., Król W. Antibiotic sensitivity of Enterobacteriaceae isolated from women vagina and uterine cervix. Med Dosw Mikrobiol 2003; 55: 4: 351-356.
  6. Tempera G., Furneri P.M. Management of aerobic vaginitis. Gynec Obstet Invest 2010; 70: 4: 244-249.
  7. Paterson D.L. Resistance in gram-negative bacteria: enterobacteriaceae. Am J Med 2006; 119: 6: Suppl 1: 20-28.
  8. Strus M., Malinowska M., Heczko P.B. In vitro antagonistic effect of Lactobacillus on organisms associated with bacterial vaginosis. J Reprod Med 2002; 47: 1: 41-46.

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