Retrospective and prospective studies were made in 611 patients with uterine myoma, who had undergone teleresolution of tumor with forced ultrasound (FU) under guidance of magnetic resonance imaging (MRI) tomography in March 2006 to March 2009. MRI&FU sessions were made on an ExAblate-2000 unit (InSightec*, Israel) under guidance of MRI 1.5 Tesla (GE, USA). The results of the study have confirmed that MRI&FU therapy is a rather safe organ-saving treatment for uterine myoma. Complications and adverse reactions were observed in 5 (1.02%) cases within the first two years of method introduction. Despite the high safety of the method and the limited list of rare complications, it should be remembered that coagulating forced ultrasound is a therapeutic agent of technology. The criteria for selecting patients and rules for performing the procedure should be strictly adhered to prevent complications and adverse reactions.