Arterial hypertension (AH) is one of the most common cardiovascular disease of the cardiovascular system. Angiotensin II, the neurohormone of therenin-angiotensin-aldosterone system, realizes its negative effects in the form of endothelial dysfunction and immune inflammation, vasoconstriction, proliferation, through type 1 AT receptors located in the peripheral vascular bed, including vessels in periodontal tissues.In the study, as the blood pressure increased and the degree of arterial hypertension increased, the blood filling of the intraosseous periodontal vessels increased, and the peripheral resistance to the blood flow increased and the elasticity of the vascular wall decreased. Increased central blood pressure, high variability of daytime blood pressure and insufficient decrease in nighttime in patients with arterial hypertension combined with chronic periodontitis are associated with significant violations of microcirculation in the periodontium and may be additional criteria for its unfavorable course, requiring additional efforts, both in terms of the effect on inflammation in the periodontium, and at an insufficiently controlled level of blood pressure. The role of arterial hypertension as an additional risk factor for the development of chronic periodontitis and a marker of its unfavorable course is discussed. The aim of the investigation is to identify the interrelations between the indicators of 24-hour blood pressure monitoring and regional blood flow in diseases of periodontal tissue in patients with periodontitis and without periodontitis. Material and methods. For registration of hemodynamics used computerized functional diagnostic dental complex ABC-01 (Russia) with software DIASTOM. Daily blood pressure monitoring (ABPM) was performed using BPLab Vasotens complex (Russia). The study groups included patients with chronic periodontitis and AG I—II stage, 1—2 degrees. Results. In patients with hypertension, with increasing blood pressure AND the degree of hypertension, there is an increase in blood filling of the intraosseous periodontal vessels and an increase in peripheral resistance to blood flow, while the elasticity of the vascular wall decreases. Conclusion. The results of the study indicate an increasing risk of periodontitis progression in patients with uncontrolled hypertension and consider hypertension as an additional risk factor for chronic periodontitis and a marker of its adverse course.