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Angotoeva I.B.

Kafedra otorinolaringologii Rossiĭskoĭ meditsinskoĭ akademii poslediplomnogo obrazovaniia

Muldasheva A.A.

Kafedra otorinolaringologii RMAPO Minzdrava Rossii, Moskva

The possibilities of conservative treatment for chronic polypous rhinosinusitis

Authors:

Angotoeva I.B., Muldasheva A.A.

More about the authors

Journal: Russian Rhinology. 2015;23(4): 57‑59

DOI: 10.17116/rosrino201523457-59

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THE POSSIBILITIES OF CONSERVATIVE TREATMENT FOR CHRONIC POLYPOUS RHINOSINUSITIS
THE POSSIBILITIES OF CONSERVATIVE TREATMENT FOR CHRONIC POLYPOUS RHINOSINUSITIS

To cite this article:

Angotoeva IB, Muldasheva AA. The possibilities of conservative treatment for chronic polypous rhinosinusitis. Russian Rhinology. 2015;23(4):57‑59. (In Russ.)
https://doi.org/10.17116/rosrino201523457-59

Подписка 2025-2 (Russian Rhinology)
 
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Objective: to optimize the treatment of polypous rhinosinusitis. Patients and methods. The investigation enrolled 62 patients with recurrent polypous rhinosinutis after endoscopic polysinusotomy. The patients were divided into 2 groups: 1) 30 people who received mometasone furoate 400 µg/day continuously for 2 months; 2) 32 people who had combined corticosteroid (CS) therapy. Results. The magnitude of symptoms considerably significantly increased in both groups 1 month after conservative treatment. Comparison of endoscopic changes established the advantage of combined CS therapy over intranasal CS monotherapy. Conclusion. Combined CS therapy for chronic rhinosinusitis with polyps that are beyond the middle meatus is more effective than intranasal CS monotherapy.

Keywords:

polypous rhinosinusitis
corticosteroid therapy

Authors:

Angotoeva I.B.

Kafedra otorinolaringologii Rossiĭskoĭ meditsinskoĭ akademii poslediplomnogo obrazovaniia

Muldasheva A.A.

Kafedra otorinolaringologii RMAPO Minzdrava Rossii, Moskva

List of references:

  1. Fokkens WJ, Lund VJ, Mullol J, Bachert C, Alobid I, Baroody F, Cervin A, Cohen N, Douglas R, Georgalas C, Gevaert P, Goossens H, Harvey R, Hellings P, Hopkins C, Jones N, Joos G, Kalogjera L, Kern B, Kowalski M, Price D, Riechelmann H, Schlosser R, Senior B, Thomas M, Toskala E, Voegels R, Wang de Y, Wormald PJ. European Position Paper on Rhinosinusitis and Nasal Polyps 2012. Rhinol Suppl. 2012;23:1-298. 
  2. Pujols L, Mullol J, Picado C. Importance of glucocorticoid receptors in upper and lower airways. Front Biosci (Landmark Ed). 2010;15:789-800.  doi:10.2741/3646.
  3. Allergicheskii rinit. Klinicheskie rekomendatsii. Praktika pediatra. Allergologiya. 2008:73-80.
  4. Mullol J, Alobid I. Combined oral and intranasal corticosteroid therapy: an advance in the management of nasal polyposis? Ann Intern Med. 2011;154(5):365-367.  doi:10.7326/0003-4819-154-5-201103010-00011.
  5. Vaidyanathan S, Barnes M, Williamson P, Hopkinson P, Donnan PT, Lipworth B. Treatment of chronic rhinosinusitis with nasal polyposis with oral steroids followed by topical steroids: a randomized trial. Ann Intern Med. 2011;154(5):293-302.  doi:10.7326/0003-4819-154-5-201103010-00003.
  6. Rajasekaran K, Seth R, Abelson A, Batra PS. Prevalence of metabolic bone disease among chronic rhinosinusitis patients treated with oral glucocorticoids. Am J Rhinol Allergy. 2010;24(3):215-219.  doi:10.2500/ajra.2010.24.3445.
  7. Lund VJ, Kennedy DW. Quantification for staging sinusitis. International conference on sinus disease: terminology, staging, therapy. Ann Otol Rhinol LaryngolSuppl. 1995;104:17-21.

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