Pathogenesis of certain neurological complications of new coronavirus infection: a foreign literature review

Bofanova N.S.; Miltykh I.S.; Zenin O.K.

doi:https://doi.org/10.17116/profmed20222508198

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OBJECTIVE OF THE REVIEW

To analyze and systematize current data on the COVID-19 effect on the central and peripheral nervous system.

MATERIAL AND METHODS

The material for the study was more than 70 papers published between 2019—2022 and indexed in the international abstract databases Scopus, Web of Science, and PubMed.

RESULTS

Analysis of the relevant literature on the pathogenesis of COVID-19 and some neurological complications was performed. It was observed that in addition to the respiratory system, SARS-CoV-2 affects the central nervous system, the peripheral nervous system, and the muscular system, resulting in neurological disorders. Understanding the pathogenesis of nervous system damage contributes to improved diagnosis of neurological complications. In general, according to the literature, patients with severe new coronavirus infection are prone to neurological complications.

CONCLUSION

Since most studies currently focus on respiratory symptoms, the prevalence of neurological effects of COVID-19 may be underestimated. A detailed analysis of the mechanisms of both central and peripheral nervous system damage is needed.

Keywords:

coronavirus infection

pathogenesis

pathogenicity

neurological symptoms

COVID-19

Authors:

Bofanova N.S.

Penza State University

ORCID: 0000-0002-5455-4987

Miltykh I.S.

Penza State University

Zenin O.K.

Penza State University

Received:

09.04.2022

Accepted:

19.05.2022

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References:

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