According to statistics, a significant number of adverse cardiovascular (CV) events occur in women with a low risk of developing cardiovascular disease (CVD). New markers are needed that go beyond traditional risk factors to identify asymptomatic women in need of active CVD prevention. As a surrogate marker for the risk of developing CVD in women, breast arterial calcifications (BAC) is proposed, which is easily detected on a mammogram, the presence of which is associated with higher CVD morbidity and mortality. A statistically significant association of BAC with coronary artery calcification (CAC), a recognized marker of coronary atherosclerosis and coronary heart disease, has been proven. The presence of BAC on a mammogram is associated with varying degrees of severity of BAC, assessed by the coronary calcium index (CCI) in a wide range of values. A statistically significant positive correlation was established between BAC and CCI >400, indicating a high probability of hemodynamically significant coronary stenoses, as well as CCI >100 and CCI >11 associated with less severe stenosis of the coronary bed. When calcinosis of the mammary gland arteries is detected in a woman, it is recommended to determine the 10-year risk of developing cardiovascular diseases according to the SCORE scale and, at a high risk level, consider the possibility of statin therapy. In women with breast arterial calcifications, who have a low and moderate risk of developing cardiovascular diseases, additional methods should be used to stratify the risk: determination of calcification of the coronary arteries, ultrasound to detect peripheral atherosclerosis, lipid spectrum assessment, and others. It is necessary to inform physicians (radiologists, cardiologists, internists) about the unfavorable prognostic significance of BAC and be sure to make a note of its presence in the conclusion based on the results of mammography.