Prevention of stomatitis in women with arterial hypertension

Kuznetsova O.Yu.; Balabolkin I.I.

doi:https://doi.org/10.17116/profmed20212407156

Kuznetsova O.Yu.

Kazan (Volga region) Federal University

Balabolkin I.I.

Research Institute of Pediatrics «National Medical Research Center for Children’s Health»

Prevention of stomatitis in women with arterial hypertension

Authors:

Kuznetsova O.Yu., Balabolkin I.I.

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Journal: Russian Journal of Preventive Medicine. 2021;24(7): 56‑59

DOI: 10.17116/profmed20212407156

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To cite this article:

Kuznetsova OYu, Balabolkin II. Prevention of stomatitis in women with arterial hypertension. Russian Journal of Preventive Medicine. 2021;24(7):56‑59. (In Russ.)
https://doi.org/10.17116/profmed20212407156

Подписка 2026 Профилактическая медицина (Russian Journal of Preventive Medicine)

Использование инфографики авторами научных работ

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Abstract:

Preventive examinations revealed women with recurrent herpetic stomatitis (RHS), suffering from arterial hypertension (AH).

OBJECTIVE

To assess the prophylaxis of immunomodulator in women with RHS aggravated by AH.

MATERIAL AND METHODS

The immunomodulator prophylaxis was carried out in 98 patients with RHS and AH aged from 28 to 45 years. Before and after prophylaxis with an antiviral agent, the patients’ immune status was assessed. The indices of local immunity of the oral cavity (SIgA), cellular (blast transformation reaction with phytohemagglutinin), humoral immunity (IgA, IgG, IgM) and C₃complement component were determined.

RESULTS

Analysis of the prophylaxis results with an immunomodulator in patients with RHS and AH revealed an increase in the immunological parameters of local immunity, i.e. approximation of their values to the values of indicators in healthy women. In the link of humoral immunity, the indicators of IgA, IgG, IgM significantly (p<0.001) increased. The levels of cellular immunity significantly (p<0.001) increased, also approaching those in the group of healthy women

CONCLUSION

The results obtained proved the clinical efficacy of the immunomodulator showing an increase in the terms of remission (p<0.001) of stomatitis in women with AH.

Keywords:

prevention

women

stomatitis

arterial hypertension

Authors:

Kuznetsova O.Yu.

Kazan (Volga region) Federal University

Balabolkin I.I.

Research Institute of Pediatrics «National Medical Research Center for Children’s Health»

Received:

24.08.2020

Accepted:

17.02.2021

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References:

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