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Gorbunov A.A.

V.I. Vernadsky Crimean Federal University, Medical Academy named after S.I. Georgievsky

Rumyanceva Z.S.

V.I. Vernadsky Crimean Federal University, Medical Academy named after S.I. Georgievsky

Reznichenko N.A.

V.I. Vernadsky Crimean Federal University, Medical Academy named after S.I. Georgievsky

Sulima A.N.

V.I. Vernadsky Crimean Federal University, Medical Academy named after S.I. Georgievsky

Gorbunova P.T.

V.I. Vernadsky Crimean Federal University, Medical Academy named after S.I. Georgievsky

MDSC expression analysis as an important marker of early delivery (a rewiew)

Authors:

Gorbunov A.A., Rumyanceva Z.S., Reznichenko N.A., Sulima A.N., Gorbunova P.T.

More about the authors

Journal: Russian Journal of Human Reproduction. 2024;30(2): 74‑79

DOI: 10.17116/repro20243002174

Read: 1342 times

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Table of contents

MDSC EXPRESSION ANALYSIS AS AN IMPORTANT MARKER OF EARLY DELIVERY (A REWIEW)
MDSC EXPRESSION ANALYSIS AS AN IMPORTANT MARKER OF EARLY DELIVERY (A REWIEW)

To cite this article:

Gorbunov AA, Rumyanceva ZS, Reznichenko NA, Sulima AN, Gorbunova PT. MDSC expression analysis as an important marker of early delivery (a rewiew). Russian Journal of Human Reproduction. 2024;30(2):74‑79. (In Russ.)
https://doi.org/10.17116/repro20243002174

Подписка 2026 Проблемы репродукции (Russian Journal of Human Reproduction)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

ANNOTATION

The frequency of preterm birth increases by 0.1% of the total number of births every year. In this regard, the aim of the study is to find the causes that can lead to early delivery and the impact on which will help reduce the negative trend. Such a factor was the suppressor cells of the myeloid germ.

AS RESEARCH METHODS

The sources of English-language scientific articles on the key searches «premature birth», «mechanism of tolerance of pregnant women», and later — «MDSC» were used.

AS A RESULT

It was found out that MDSC is a mechanism for the formation of tolerance in pregnant women to the developing fetus, and the mechanisms that regulate MDSC are found not only during pregnancy, but also in malignant immune-dependent diseases. Available medications that can affect immunity tolerance may be useful for prolonging pregnancy.

DISCUSSION

The results obtained are fully confirmed by the available data on early delivery, which allows us to consider MDSC as a leading factor in physiological immune tolerance in pregnant women

Keywords:

MDSC
myeloid germ suppressor cells
premature birth

Authors:

Gorbunov A.A.

V.I. Vernadsky Crimean Federal University, Medical Academy named after S.I. Georgievsky

Rumyanceva Z.S.

V.I. Vernadsky Crimean Federal University, Medical Academy named after S.I. Georgievsky

Reznichenko N.A.

V.I. Vernadsky Crimean Federal University, Medical Academy named after S.I. Georgievsky

Sulima A.N.

V.I. Vernadsky Crimean Federal University, Medical Academy named after S.I. Georgievsky

Gorbunova P.T.

V.I. Vernadsky Crimean Federal University, Medical Academy named after S.I. Georgievsky

Received:

18.01.2023

Accepted:

20.05.2023

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References:

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