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Ivanets T.Iu.

FGBU "Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova" Minzdravsotsrazvitiia Rossii, Moskva

Alekseeva M.L.

FGBU "Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova" Minzdravsotsrazvitiia Rossii, Moskva

Kolod'ko V.G.

FGBU "Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova" Minzdrava Rossii, Moskva

DIAGNOSTIC VALUE OF ALFA-FETOPROTEIN IN ONCOLOGY, PERINATOLOGY AND NEONATOLOGY (A REVIEW)

Authors:

Ivanets T.Iu., Alekseeva M.L., Kolod'ko V.G.

More about the authors

Read: 24267 times


To cite this article:

Ivanets TIu, Alekseeva ML, Kolod'ko VG. DIAGNOSTIC VALUE OF ALFA-FETOPROTEIN IN ONCOLOGY, PERINATOLOGY AND NEONATOLOGY (A REVIEW). Russian Journal of Human Reproduction. 2012;(6):14‑19. (In Russ.)

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References:

  1. Alekseeva M.L. AFP. Ispol'zovanie v onkologii i perinatologii. Probl reprod 2000; 3: 13-19.
  2. Alekseeva M.L., Pustotina O.A., Fanchenko N.D., Pankratova T.S. AFP kak prognosticheskii pokazatel' sostoyaniya novorozhdennogo. Probl reprod 2005; 5: 10-15.
  3. Bakharev V.A., Karetnikova V.A., Alekseeva M.L., Kolod'ko V.G., Stygar A.M. Informativnost' skriningovykh programm v diagnostike patologii ploda. Akush i ginekol 2008; 6: 29-33.
  4. Ekimova E.V., Alekseeva M.L., Kolod'ko V.G., Ivanets T.Yu., Pustotina O.A. Al'fa-fetoprotein i Β2-mikroglobulin kak prognosticheskie pokazateli sostoyaniya novorozhdennykh. Probl reprod 2010; 2: 97-101.
  5. Ivanets T.Yu., Alekseeva M.L., Ekimov A.N., Ekimova E.V., Kolod'ko V.G., Pankratova T.S. Nekotorye biologicheskie markery v akusherstve, perinatologii i neonatologii. Probl reprod 2011; 3: 97-101.
  6. Abelev G.I. Alpha-fetoprotein in ontogenesis and its association with malignant tumors. Advanc Cancer Res 1971; 14: 295-358.
  7. Abelev G.I. Alpha-fetoprotein as a marker of embryo-specific differentiation's in normal and tumor tissues. Transplantation 1974; 20: 3-37.
  8. Abelev G.I. Alpha-fetoprotein: the genesis. Oncodevelopmental Biol Med 1983; 4: 371-381.
  9. Abelev G.I. Antigenic structure of cemistry-induced hepatomas. Progr Exp Tumor Res 1965; 7: 104-157.
  10. Abelev G.I. Study of the regulation of alpha-fetoprotein synthesis in ontogenesis and carcinogenesis. Sov Sci Rev Sect D Biol Rev (New York) 1980; l: 371-397.
  11. Abelev G.I., Perova S., Khramkova N.I. et al. Production of embryonal alpha-globulin by the transplantable mouse hepatomas. Transplantation 1963; 5: 174-180.
  12. Aitken D.A., Crossley J.A. Neural tube defects/ alpha-fetoprotein/Down's syndrome screening. Curr Opin Obstet Gynecol 1997; 9-2: 113-120.
  13. Alembik Y., Dott V., Roth M.P., Stoll S. Prevalence of neural tube defects in northeastern France, 1979-1992 impact of prenatal diagnosis. Ann Genet 1995; 38-1: 49-53.
  14. Arends J. et al. Prenatal screening for neural-tube defects, quality specification of maternal serum alpha-fetoprotein analysis. Ups J Med Sci 1993; 98-3: 339-347.
  15. Barnabei V.M., Krantz D.A., Macri J.N., Larsen J.M. Enhanced twin pregnancy detection within an open neural tube defect and Down syndrome screening protocol using free-beta hcg and AFP. Prenat Diagn 1995; l5-12: 1131-1134.
  16. Bergstrand C.G., Craz B. Demonstration of a new protein fraction in serum from the human fetus. Scand J Din Lab Invest 1956; 8: 174-179.
  17. Brock D.G.H., Bolton A.T. Prenatal diagnosis of anencephaly through maternal serum alpha-fetoprotein. Scand J Din Lab Invest 1973; 2: 923-924.
  18. Chen C.P., Chern S.R., Liu F.F. et al. Prenatal diagnosis of a deletion of 18q in a fetus associated with multiple-marker screen positive results. Prenat Diagn 1997; 17-6: 571-576.
  19. Clarke P.C., Gordon Y.B., Kitau M.J. et al. Alpha-fetoprotein levels in pregnancies complicated by gastrointestinal abnormalities of the fetus. Br J Obstet Gynec 1977; 84-4: 285-289.
  20. Cohen V., Graham H., Lorrin Lau H. Alpha-1 fetoprotein in pregnancy. Am J Obstet Gynec 1973; l5-7: 881-883.
  21. Cuckle H., Densem J., Wald N. Repeat maternal serum testing in multiple marker Down's syndrome screening programmes. Prenat Diagn 1994; 14-7: 603-607.
  22. Dick P.T. Periodic health examination, 1996 update: 1. Prenatal screening for and diagnosis of Down syndrome. Canadian Task Force on the Periodic Health Examination. Can Med Ass J 1996; 54-4: 465-479.
  23. Edeling C.I., Schioler V., Thisted I. Alpha-fetoprotein in cord serum correlated togestationae age. Acta Obstet Gynec Scand 1977; 56-1: 15-17.
  24. Fourth Report of the UK collaborative study on AFP in relation to neural-tube defects. Estimating an individual's risk of having a fetus with open spina bifida and the value of repeat AFP-testing. J Epid Comm Hith 1982; 36: 87-95.
  25. Gaspard U.Y., Reuter A.M., Delive Y.L. Trophoblastic tumors. Clin Endocr 1998; 13: 319-329.
  26. Gibbs P., Zielinski R., Boyd C., Dugaiczyk A. Structure, polymorphism, and novel repeated DNA elements revealed by a complete sequence of human alpha-fetoprotein gene. Biochemistry 1987; 26: 1332-1343.
  27. Gitlin D., Pericelli A. Giti in G. Synthesis of alpha-fetoprotein by liver, yolk sac and gastrointestinal tract of the human concepts. Cancer Res 1972; 32: 979-982.
  28. Guertin M., La Rue H., Bemier D. et al. Enhancer and promoter elements directing activation and glucocorticoid repression of the alpha-fetoprotein gene in hepatocytes. Mol Cell Biol 1988; 8: 1398-1407.
  29. Harper M.E., Dugaiczyk A. Linkage of the evolutionary related serum albumin and alpha-fetoprotein genes within ql 1-22 of human chromosome 4. Am J Hum Genet 1994; 35: 565-572.
  30. Masopust J., Kithier R., Radi I. et al. Occurrence of fetoprotein in patients with neoplasms and non-neoplastic disease. Int J Cancer 1967; 2: 551-558.
  31. Masseyeff R. Human alpha-fetoprotein (review). Path Biol 1972; 20: 703-727.
  32. Mikulikova L., Struplova J., Fialova L., Malbohan I. Disorders of fetoplacental function in pregnant women with diabetes. Sb Lek 1993; 94-2: 173-177.
  33. Morssink L.P., Sikkema-Raddatz V., Beekhuis J.R. et al. Placental mosaicism is associated with unexplained second-trimester elevation of MSHCG levels, but not with elevation of MSAFP levels. Prenat Diagn 1996; 16-9: 845-851.
  34. Nunez E., Benassayag C., Grysteff N. et al. Estrogen and fatty acid binding properties of murine AFP: a guide to explain some biological activities of this protein. Eds G. Mizejewski, H. Jacobson. Biol Activ Alpha-Fetoprotein 1987; 1: 3-18.
  35. Petry M. Elevation of maternal alpha-fetoprotein in systemic lupus erythematosus: a controlled study. J Reumatol 1995; 22-7: 1365-1368.
  36. Piggott M., Wilkinson P., Bennett J. Impelementation of an antenatal serum screening programme for Down's syndrome in two districts (Brighton and Eastbourne). The Brighton and Eastbourne Down's Syndrome Screening Group. J Med Screen 1994; 1-1: 45-49.
  37. Ruoslahti E., Seppala M. Alpha-fetoprotein in cancer and fetal development. Advanc Cancer Res 1979; 29: 275-346.
  38. Schittger A., Liedgren S., Reedberg S. et al. Raised maternal serum and amniotic fluid alpha-fetoprotein levels associated with a placental haemangioma. Case report. Br J Obstet Gynec 1980; 87-9: 824-826.
  39. Smith C., Kelleher Ph. Biological Activities of Alpha-Fetoprotein. Eds G. Mizejeweski, H. Jacobson 1989; 2: 35-43.
  40. Takayma H. A case of bladder cancer producing alpha-fetoprotein (AFP). Hinyokika Kyio 1995; 41-5: 387-389.
  41. Taketa K. Alpha-fetoprotein: reevaluation in gepatology. Hepatology 1990; 12-6: 1420-1432.
  42. Tatarinov Y.S. Presence ofembryonal alpha-globulin in the serum of patient with primary hepatocellular carcinoma. Vopr Med Chirmi 1964; 10: 90-91.
  43. Toftager-Larsen K., Benzie R.I., Doran T.A. et al. Alpha-fetoprotein and ultrasound scanning in the prenatal diagnosis of Terner's syndrome. Prenat Diagn 1983; 3-1: 35-40.
  44. Wald N.J., Densem J.W., Smith D., Klee G.G. Four-marker serum screening for Down's syndrome. Prenat Diagn 1994; 14-8: 707-716.
  45. Waller D.K., Lustig L.S., Cunningham G.C. et al. The association between maternal serum alpha-fetoprotein and preterm birth, small for gestational age infants, preeclampsia, and placental complications. Obstet Gynecol 1996; 88-5: 816-822.

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