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Sidorova Yu.S.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia

Skalnaya M.G.

RUDN University, Moscow, Russia

Tinkov A.A.

RUDN University, Moscow, Russia;
P.G. Demidov State University of Yaroslavl, Yaroslavl, Russia

Mazo V.K.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia

The effect of vanadium compounds on carbohydrate and lipid metabolism disorders

Authors:

Sidorova Yu.S., Skalnaya M.G., Tinkov A.A., Mazo V.K.

More about the authors

Journal: Problems of Endocrinology. 2019;65(3): 184‑190

DOI: 10.14341/probl10093

Read: 3388 times

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Table of contents

THE EFFECT OF VANADIUM COMPOUNDS ON CARBOHYDRATE AND LIPID METABOLISM DISORDERS
THE EFFECT OF VANADIUM COMPOUNDS ON CARBOHYDRATE AND LIPID METABOLISM DISORDERS

To cite this article:

Sidorova YuS, Skalnaya MG, Tinkov AA, Mazo VK. The effect of vanadium compounds on carbohydrate and lipid metabolism disorders. Problems of Endocrinology. 2019;65(3):184‑190. (In Russ.)
https://doi.org/10.14341/probl10093

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Abstract:

At this stage in the development of nutriciological science, it has not been established if biologically active substances are essential to the human body; however, an explanation of the physiological role of minor biologically active substances is necessary to clarify the qualitative composition of Nutrioma. Of particular interest is the transition metal, vanadium. Adding vanadium to the diet of animals with induced or genetically determined type 2 diabetes mellitus normalizes glucose and blood insulin levels, reduces insulin resistance, promotes β-cell regeneration, and has a beneficial effect on lipid metabolism. Clinical studies of the effectiveness of vanadium are not convincing, in most part, because of their insufficient duration. The review briefly discusses the main mechanisms of the action of vanadium compounds. Therapeutic doses of vanadium compounds may overlap with toxic doses. Organic vanadium compounds could be used in significantly lower doses. The main problem with the possible use of vanadium compounds in antidiabetic therapy is the balance between their beneficial effects and the connected risks of side effects.

Keywords:

vanadium
vanadium compounds
carbohydrate metabolism
lipid metabolism
insulin resistance
toxicity
review

Authors:

Sidorova Yu.S.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia

Skalnaya M.G.

RUDN University, Moscow, Russia

Tinkov A.A.

RUDN University, Moscow, Russia;
P.G. Demidov State University of Yaroslavl, Yaroslavl, Russia

Mazo V.K.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia

Close metadata

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