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Mazo V.K.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia

Sidorova Yu.S.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia

Shipelin V.A.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia

Petrov N.A.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia

Kochetkova A.A.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia

Polyphenolic plant extracts: effects on disorders of carbohydrate and lipid metabolism in laboratory animals

Authors:

Mazo V.K., Sidorova Yu.S., Shipelin V.A., Petrov N.A., Kochetkova A.A.

More about the authors

Journal: Problems of Endocrinology. 2016;62(4): 38‑44

DOI: 10.14341/probl201662438-44

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Table of contents

POLYPHENOLIC PLANT EXTRACTS: EFFECTS ON DISORDERS OF CARBOHYDRATE AND LIPID METABOLISM IN LABORATORY ANIMALS
POLYPHENOLIC PLANT EXTRACTS: EFFECTS ON DISORDERS OF CARBOHYDRATE AND LIPID METABOLISM IN LABORATORY ANIMALS

To cite this article:

Mazo VK, Sidorova YuS, Shipelin VA, Petrov NA, Kochetkova AA. Polyphenolic plant extracts: effects on disorders of carbohydrate and lipid metabolism in laboratory animals. Problems of Endocrinology. 2016;62(4):38‑44. (In Russ.)
https://doi.org/10.14341/probl201662438-44

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Abstract:

Modern nutrition has clear evidence of the involvement into the metabolism of many minor food components, which were not previously discussed as factors necessary for life support of health and ill human. One of the innovative approaches to the creation of a new generation of specialized food products for the dietary treatment of type 2 diabetes is a targeted use in their composition plant minor biologically active food substances with proven significant hypoglycemic, cholesterol-lowering and antioxidant action as a «micro-ingredients». Promising sources of natural functional food ingredients for the dietary treatment and prevention of type 2 diabetes and its attendant complications are plant extracts with a high content of natural polyphenolic compounds. The natural polyphenolic compounds include flavonoids, obligate food antioxidants what is the reason of their hypoglycemic and/or lipid-lowering effects. However, we consume no individual flavonoids, but their mixtures, with plant food. Data about antidiabetic properties of plant extracts containing various combinations of flavonoids are very important in the framework of the problem of dietary correction and prevention of type 2 diabetes from the position of clinical nutrition. The review briefly discusses the effect of green tea, bilberry leaves and bean coats plant extracts on disorders of carbohydrate and lipid metabolism in laboratory animals with experimentally or genetically determined diabetes. The presented analysis of publications shows that the results of experimental studies in vitro and in vivo confirm the antioxidant, hypoglycemic and/or hypolipidemic effect of polyphenolic plant extracts. It was concluded that the inclusion of plant extracts of flavonoids in the specialized food products for targeted nutritional correction and/or prevention of metabolic disorders of type 2 diabetes is a promising direction.

Keywords:

type 2 diabetes
clinical nutritiology
polyphenols
flavonoids
plant extracts
review

Authors:

Mazo V.K.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia

Sidorova Yu.S.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia

Shipelin V.A.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia

Petrov N.A.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia

Kochetkova A.A.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia

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