The effect of the complex application of microneedling and laser therapy on the qualitative characteristics of the skin with involutive changes

Avagumyan M.A.; Kruglova L.S.; Ikonnikova E.V.

doi:https://doi.org/10.17116/plast.hirurgia202202163

Avagumyan M.A.

Central State Medical Academy of Administrative Directorate of the President of the Russian Federation;
Medical Research and Education Center Lomonosov Moscow State University (University Clinic)

Kruglova L.S.

Central State Medical Academy of Department of Presidential Affairs

Scopus AuthorID: 24168854300
ORCID: 0000-0002-5044-5265

Ikonnikova E.V.

Central State Medical Academy of Administrative Directorate of the President of the Russian Federation;
Institute of Plastic Surgery and Cosmetology

The effect of the complex application of microneedling and laser therapy on the qualitative characteristics of the skin with involutive changes

Authors:

Avagumyan M.A., Kruglova L.S., Ikonnikova E.V.

More about the authors

Journal: Plastic Surgery and Aesthetic Medicine. 2022;(2): 63‑70

DOI: 10.17116/plast.hirurgia202202163

Read: 4313 times

To cite this article:

Avagumyan MA, Kruglova LS, Ikonnikova EV. The effect of the complex application of microneedling and laser therapy on the qualitative characteristics of the skin with involutive changes. Plastic Surgery and Aesthetic Medicine. 2022;(2):63‑70. (In Russ., In Engl.)
https://doi.org/10.17116/plast.hirurgia202202163

Подписка 2026 Пластическая хирургия и эстетическая медицина (Plastic Surgery and Aesthetic Medicine)

Использование инфографики авторами научных работ

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THE RELEVANCE OF RESEARCH

To date, microneedling has found its application in clinical practice, due to the simplicity of the device and the methodology of the procedure. The unique, minimally invasive method can serve as a way to conduct physical factors (radio frequency), cell preparations (PRP), drugs (minoxidil, depigmenting serum, transenamic acid). However, many questions regarding the use of microneedling in aesthetic medicine remain open and require further study, including in terms of the possibility of combined use with other techniques.

MATERIAL AND METHODS

Under observation were 82 patients aged 40 to 50 years. Patients were divided into 3 groups depending on the therapy. To study the effectiveness, a study was carried out on qualitative characteristics: hydration (corneometry), skin elasticity (cutometry) and the level of hyperpigmentation (mexametry), as well as the clinical characteristics of the skin, assessed by an 11-point visual analogue scale (VAS).

RESULTS

Humidity increased in the 1st group by 17.5%, in the 2nd group by 23.7%, in the 3rd group by 24.8%. With regard to skin elasticity, the change in indicators was comparable in all groups. The decrease in the mexometric index averaged: in the 1st group — 34.5%, in the 2nd group — 71.3%, in the 3rd group — 86.7%. The total indicator of clinical changes (VAS score) decreased in the 1st group by 1.8 times (p=0.0215), in the 2nd group — by 3.1 times (p=0.0275), in the 3rd group — by 5.3 times (p=0.0062).

CONCLUSIONS

The combined use of microneedling and Er:Glass laser increases skin hydration and elasticity, reduces the severity of wrinkles and pigmentation, which underlies a high clinical effect in correcting involutive skin changes.

Keywords:

involutive skin changes

microneedling

laser therapy

corneometry

cutometry

meksametry

qualitative characteristics of the skin

Authors:

Avagumyan M.A.

Central State Medical Academy of Administrative Directorate of the President of the Russian Federation;
Medical Research and Education Center Lomonosov Moscow State University (University Clinic)

Kruglova L.S.

Central State Medical Academy of Department of Presidential Affairs

Scopus AuthorID: 24168854300
ORCID: 0000-0002-5044-5265

Ikonnikova E.V.

Central State Medical Academy of Administrative Directorate of the President of the Russian Federation;
Institute of Plastic Surgery and Cosmetology

Received:

30.01.2022

Accepted:

15.02.2022

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References:

Fabbrocini G, De Vita V, Pastore F, Annunziata MC, et al. Collagen induction therapy for the treatment of upper lip wrinkles. J Dermatolog Treat. 2012;23:144-152. https://doi.org/10.3109/09546634.2010.544709
Fernandes D. Minimally invasive percutaneous collagen induction. Oral Maxillofac Surg Clin North Am. 2005;17:51-63. https://doi.org/10.1016/j.coms.2004.09.004
Jasin M. Achieving superior resurfacing results with the erbium:YAG laser. Arch Facial Plast Surg. 2002;4:262-266. https://doi.org/10.1001/archfaci.4.4.262
Patil UA, Ld D. Overview of lasers. Indian J Plast Surg. 2008;41(suppl):101-113.
Cohen M, Spann M, Nolan WB. Skin resurfacing, Erbium YAG laser. Facial Plastic Surgery Clinics of North America. 2001;9(2):291-302. https://doi.org/10.1016/j.fsc.2004.03.005
Pozner JN, Goldberg DJ. Superficial erbium: YAG laser resurfacing of photo damaged skin. J Cosmet Laser Ther. 2006;8:89-91. https://doi.org/10.1080/14764170600717852
Weniger FG, Weidman AA, Barrero Castedo CE. Full-Field Erbium:YAG Laser Resurfacing: Complications and Suggested Safety Parameters. Aesthet Surg J. 2020;40(6):374-385. https://doi.org/10.1093/asj/sjz319
Paasch U, Said T. Stimulation of collagen and elastin production in-vivo using 1,540 nm Er:Glass laser: assessment of safety and efficacy. J Cosmet Laser Ther. 2020;22(2):77-83. https://doi.org/10.1080/14764172.2020.1728339
Triana L, Cuadros SC, Triana C, Barbato C, Zambrano M. Laser resurfacing for Latin skins: The experience with 665 cases. Aesthetic Plast Surg. 2015;39(4):582-588. https://doi.org/10.1007/s00266-015-0489-5
Modena DAO, Miranda ACG, Grecco C, Liebano RE, Cordeiro RCT, Guidi RM. Efficacy, safety, and guidelines of application of the fractional ablative laser erbium YAG 2940 nm and non-ablative laser erbium glass in rejuvenation, skin spots, and acne in different skin phototypes: A systematic review. Lasers Med Sci. 2020;35(9):1877-1888. https://doi.org/10.1007/s10103-020-03046-7
Aust MC, Reimers K, Kaplan HM, et al. Percutaneous collagen induction-regeneration in place of cicatrisation? J Plast Reconstr Aesthet Surg. 2011;64(1);97-107. https://doi.org/10.1016/j.bjps.2010.03.038
Ramaut L, Hoeksema H, Pirayesh A, Stillaert F, Monstrey S. Microneedling: Where do we stand now? A systematic review of the literature. J Plast Reconstr Aesthet Surg. 2018;71(1):1-14. https://doi.org/10.1016/j.bjps.2017.06.006
Zeitter S, Sikora Z, Jahn S, et al. Microneedling: matching the results of medical needling and repetitive treatments to maximize potential for skin regeneration. Burns. 2014;40(5):966-973. https://doi.org/10.1016/j.burns.2013.12.008
McCrudden MTC, McAlister E, Courtenay AJ, González-Vázquez P, Raj Singh TR, Donnelly RF. Microneedle applications in improving skin appearance. Exp Dermatol. 2015;24(8):561-566. https://doi.org/10.1111/exd.12723
El-Domyati M, Barakat M, Awad S, Medhat W, El-fakahany H, Farag H. Multiple microneedling sessions for minimally invasive facial rejuvenation: An objective assessment. Int J Dermatol. 2015;54(12):1361-1369. https://doi.org/10.1111/ijd.12761
Chawla S. Split face comparative study of microneedling with PRP versus microneedling with vitamin C in treating atrophic post acne scars. J Cutan Aesthet Surg. 2014;7:209-212. https://doi.org/10.4103/0974-2077.150742
Busch KH, Bender R, Walezko N, Aziz H, Altintas MA, Aust M.C. Combination of medical needling and non-cultured autologous skin cell transplantation (ReNovaCell) for repigmentation of hypopigmented burn scars. Burns. 2016;42(7):1556-1566. https://doi.org/10.1016/j.burns.2016.04.009
Hou A, Cohen B, Haimovic A, Elbuluk N. Microneedling: A Comprehensive Review. Dermatol Surg. 2014;43(3):321-339. https://doi.org/10.1097/DSS.0000000000000924
Waghule T, Singhvi G, Dubey SK, Pandey MM, Gupta G, Singh M, Dua K. Microneedles: A smart approach and increasing potential for transdermal drug delivery system. Biomed Pharmacother. 2019;109:1249-1258. https://doi.org/10.1016/j.biopha.2018.10.078
Alenichev AYu, Kruglova LS, Fedorov SM, Sharypova IV. Evaluation of the effectiveness of the use of micro-needle RF therapy in the correction of involutive changes in the skin of the face and neck. Fizioterapevt. 2017;4:4-13. (In Russ.).
Alenichev AYu, Kruglova LS, Fedorov SM, Sharypova IV, Ast NA. Combined use of RF-microneedle therapy and injections of platelet-rich plasma activated by autologous thrombin in aesthetic medicine. Fizioterapiya, bal’neologiya, reabilitatsiya. 2017;16(6):320-324. (In Russ.). https://doi.org/10.18821/1681-3456-2017-16-5-320-324
Min S, Park SY, Yoon JY, Suh DH. Comparison of fractional microneedling radiofrequency and bipolar radiofrequency on acne and acne scar and investigation of mechanism: comparative andomized controlled clinical trial. Arch Dermatol Res. 2015;307(10):897-904. https://doi.org/10.1007/s00403-015-1601-z
Alessa D, Bloom JD. Microneedling Options for Skin Rejuvenation, Including Non-temperature-controlled Fractional Microneedle Radiofrequency Treatments. Facial Plast Surg Clin North Am. 2020;28(1):1-7. https://doi.org/10.1016/j.fsc.2019.09.001
Alster TS, Graham PM. Microneedling: A Review and Practical Guide. Dermatol Surg. 2018;44(3):397-404. https://doi.org/10.1097/DSS.0000000000001248