Time course of changes in the cavity volume of soft tissue abscess during its combined treatment in an experiment

Alipov V.V.

V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia, Saratov, Russia

Urusova A.I.

V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia, Saratov, Russia

Lebedev M.S.

V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia, Saratov, Russia

Andreev D.A.

M.F. Vladimirsky Moscow Regional Research Clinical Institute, Ministry of Health of the Moscow Region, Moscow, Russia

ORCID: 0000-0003-0745-9474

Zhelaev M.V.

V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia, Saratov, Russia

Time course of changes in the cavity volume of soft tissue abscess during its combined treatment in an experiment

Authors:

Alipov V.V., Urusova A.I., Lebedev M.S., Andreev D.A., Zhelaev M.V.

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Journal: Russian Journal of Operative Surgery and Clinical Anatomy. 2017;1(1): 49‑52

DOI: 10.17116/operhirurg20171149-52

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To cite this article:

Alipov VV, Urusova AI, Lebedev MS, Andreev DA, Zhelaev MV. Time course of changes in the cavity volume of soft tissue abscess during its combined treatment in an experiment. Russian Journal of Operative Surgery and Clinical Anatomy. 2017;1(1):49‑52. (In Russ.)
https://doi.org/10.17116/operhirurg20171149-52

Подписка 2025-2 (Russian Journal of Operative Surgery and Clinical Anatomy)

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Objective. To estimate the time course of changes in the volume of soft tissue abscess (STA) during its combined surgical treatment using eplan-based zinc oxide nanoparticles (ZONs). Material and methods. In 80 experiments, Staphylococcus-induced STA was simulated in four groups of laboratory animals (male rats weighing 250±50 g); Group 4 animals received combined surgical treatment using eplan-based ZONs. Results. The combined use of Eplan and ZONs contributes to the accelerated regeneration process, reduced abscess cavity, and almost complete cavity obliteration just at 10 postoperative days. Conclusion. Combined surgical treatment, by strengthening the processes of collagenosis and tissue epithelialization, creates optimal conditions for cavity obliteration and results in a twofold reduction in the time of abscess treatment.

Keywords:

soft tissue abscess

abscess cavity volume

experiment

simulation

Authors:

Alipov V.V.

V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia, Saratov, Russia

Urusova A.I.

V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia, Saratov, Russia

Lebedev M.S.

V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia, Saratov, Russia

Andreev D.A.

M.F. Vladimirsky Moscow Regional Research Clinical Institute, Ministry of Health of the Moscow Region, Moscow, Russia

ORCID: 0000-0003-0745-9474

Zhelaev M.V.

V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia, Saratov, Russia

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