Computed tomography-guided transthoracic biopsy of a tumor of the single functioning lung

Shrainer I.V.; Esakov Yu.S.; Tukvadze Z.G.

doi:https://doi.org/10.17116/onkolog20221105160

Shrainer I.V.

Moscow City Oncology Hospital No. 1

Esakov Yu.S.

Moscow City Oncology Hospital No. 1

Tukvadze Z.G.

Moscow City Oncology Hospital No. 1

Computed tomography-guided transthoracic biopsy of a tumor of the single functioning lung

Authors:

Shrainer I.V., Esakov Yu.S., Tukvadze Z.G.

More about the authors

Journal: P.A. Herzen Journal of Oncology. 2022;11(5): 60‑64

DOI: 10.17116/onkolog20221105160

Read: 1364 times

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Shrainer IV, Esakov YuS, Tukvadze ZG. Computed tomography-guided transthoracic biopsy of a tumor of the single functioning lung. P.A. Herzen Journal of Oncology. 2022;11(5):60‑64. (In Russ.)
https://doi.org/10.17116/onkolog20221105160

Подписка 2026 Онкология. Журнал им. П.А. Герцена (P.A. Herzen Journal of Oncology)

Использование инфографики авторами научных работ

Close metadata

Recommended articles:

CT in planning of heart valve surgery through minithoracotomy. Pirogov Russian Journal of Surgery. 2024;(12-2):127-133

Magnetic resonance imaging and PET/CT with 11C-methionine for primary central nervous system vasculitis. Burdenko's Journal of Neurosurgery. 2024;(6):71-76

Clinical and tomographic comparisons in patients with aphasia in the acute period of ischemic stroke. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(12-2):27-33

Determination of formation age of acute traumatic intracranial subdural hematomas using computed tomography. Forensic Medical Expertise. 2025;(1):17-21

Possibilities of computed tomography of lungs in diagnosis and differential diagnosis of hypersensitive pneumonitis (literature review). Journal of Respiratory Medicine. 2025;(1):23-29

CT imaging in the treatment of ventral hernias. Pirogov Russian Journal of Surgery. 2025;(5):86-95

Endoscopic resection of a giant tumor of the submucosal layer of the stomach causing periodic stenosis of its outlet. Endoscopic Surgery. 2025;(3):69-76

Sacral dysmorphism in patients with traumatology and orthopedics. Russian Journal of Operative Surgery and Clinical Anatomy. 2025;(2):30-37

X-ray anatomical characteristics of age-related changes in the human craniofacial region using the zygomatico-orbital complex as an example. Russian Journal of Operative Surgery and Clinical Anatomy. 2025;(2-2):104-109

Primary-chronic osteomyelitis and fibrous dysplasia of the mandible in children. Differential diagnosis and treatment. Stomatology. 2025;(4):41-48

Abstract:

The paper describes a case of computed tomography (CT)-guided transthoracic biopsy (TTB) of a neoplasm of the single functioning lung in a 69-year-old patient with polyneoplasm of the lung and prostate. During the current treatment for lung cancer, the patient noted the progression of the process as an appearance and increase of foci in the right lung. After a previous left upper lobectomy and subsequent external beam radiation therapy, the patient developed fibroatelectasis of the remaining left lower lobe. The purpose of the biopsy is to identify the source of metastasis, to conduct a molecular genetic study of the tumor, and to choose therapy. The patient underwent CT-guided TTB using stepwise and coaxial procedures. Histological and immunohistochemical studies confirmed the presence of lung adenocarcinoma metastasis. A molecular genetic study revealed EGRF gene exon 19 and 20 mutations, which made it possible to change the therapy.

Keywords:

computed tomography

CT-guided transthoracic biopsy

single lung

Authors:

Shrainer I.V.

Moscow City Oncology Hospital No. 1

Esakov Yu.S.

Moscow City Oncology Hospital No. 1

Tukvadze Z.G.

Moscow City Oncology Hospital No. 1

Received:

13.04.2022

Accepted:

15.05.2022

Close metadata

References:

Zhang P, Liu JM, Zhang YY, Hua R, Xia FF, Shi YB. Computed tomography-guided lung biopsy: a meta-analysis of low-dose and standard-dose protocols. J Cancer Res Ther. 2021;17(3):695-701. https://doi.org/10.4103/jcrt.JCRT_1274_20
Fu YF, Li GC, Cao W, Wang T, Shi YB. Computed tomography fluoroscopy-guided versus conventional computed tomography-guided lung biopsy: a systematic review and meta-analysis. J Comput Assist Tomogr. 2020;44(4):571-577. https://doi.org/10.1097/RCT.0000000000001044
Manhire A, Charig M, Clelland C, Gleeson F, Miller R, Moss H, Pointon K, Richardson C, Sawicka E; BTS. Guidelines for radiologically guided lung biopsy. Thorax. 2003;58(11):920-936. https://doi.org/10.1136/thorax.58.11.920
Yoon SH, Lee SM, Park CH, Lee JH, Kim H, Chae KJ, Jin KN, Lee KH, Kim JI, Hong JH, et al. 2020 Clinical practice guideline for percutaneous transthoracic needle biopsy of pulmonary lesions: a consensus statement and recommendations of the Korean Society of Thoracic Radiology. Korean J Radiol. 2021;22(2):263-280. https://doi.org/10.3348/kjr.2020.0137
O’Neill AC, McCarthy C, Ridge CA, Mitchell P, Hanrahan E, Butler M, Keane MP, Dodd JD. Rapid needle-out patient-rollover time after percutaneous CT-guided transthoracic biopsy of lung nodules: effect on pneumothorax rate. Radiology. 2012;262(1):314-319. https://doi.org/10.1148/radiol.11103506
Cronin CG, Sharma A, Digumarthy SR, Gilman MD, McLoud T, Muse VV, Shepard JO. Percutaneous lung biopsy after pneumonectomy: factors for improving success in the care of patients at high risk. AJR Am J Roentgenol. 2011;196(4):929-934. https://doi.org/10.2214/AJR.10.4920
Klein JS, Zarka MA. Transthoracic needle biopsy. Radiol Clin North Am. 2000;38(2):235-266. https://doi.org/10.1016/s0033-8389(05)70161-5
Khankan AA, Al-Muaikeel M. Image-guided percutaneous transthoracic biopsy in lung cancer — emphasis on CT-guided technique. J Infect Public Health. 2012;5(suppl 1):22-30. https://doi.org/10.1016/j.jiph.2012.09.001
Mohammed TLH, White CS, Yankelevitz DF. Percutaneous needle biopsy in single lung patients. J Comput Assist Tomogr. 2006;30(2):267-269. https://doi.org/10.1097/00004728-200603000-00019
Sangha BS, Hague CJ, Jessup J, O’Connor R, Mayo JR. Transthoracic computed tomography-guided lung nodule biopsy: comparison of core needle and fine needle aspiration techniques. Can Assoc Radiol J. 2016;67(3):284-289. https://doi.org/10.1016/j.carj.2015.10.005
Watane GV, Hammer MM, Barile MF. CT-guided core-needle biopsy of the lung is safe and more effective than fine-needle aspiration biopsy in patients with hematologic malignancies. Radiol Cardiothorac Imaging. 2019;1(5):e180030. https://doi.org/10.1148/ryct.2019180030
Kim JH, Kim HS, Choi JS, Lee KM, Shin YC, Ahn BM, Choi DR, Kwon JH, Park S, Kim HY, et al. Bilateral subdural hemorrhage as a possible adverse event of gefitinib in a patient with non-small cell lung cancer. Lung Cancer. 2009;64(1):121-123. https://doi.org/10.1016/j.lungcan.2008.10.007
Yan DF, Yan SX, Yang JS, Wang YX, Sun XL, Liao XB, Liu JQ. Hemorrhage of brain metastasis from non-small cell lung cancer post gefitinib therapy: two case reports and review of the literature. BMC Cancer. 2010;10:49. https://doi.org/10.1186/1471-2407-10-49