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Deshkina T.I.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdravsotsrazvitiia Rossii

Kornietskaia A.L.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdrava Rossii

Bolotina L.V.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdravsotsrazvitiia Rossii

Toxicity and efficacy of panitumumab in metastatic colorectal cancer

Authors:

Deshkina T.I., Kornietskaia A.L., Bolotina L.V.

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Journal: P.A. Herzen Journal of Oncology. 2013;2(6): 51‑55

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To cite this article:

Deshkina TI, Kornietskaia AL, Bolotina LV. Toxicity and efficacy of panitumumab in metastatic colorectal cancer. P.A. Herzen Journal of Oncology. 2013;2(6):51‑55. (In Russ.)

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The paper describes two clinical cases of using the targeted drug panitumumab in patients with metastatic colorectal cancer. It evaluates the direct efficiency of this treatment option and its related skin toxicity.

Keywords:

colorectal cancer
panitumumab
skin toxicity

Authors:

Deshkina T.I.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdravsotsrazvitiia Rossii

Kornietskaia A.L.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdrava Rossii

Bolotina L.V.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdravsotsrazvitiia Rossii

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  12. Amado R.G., Wolf M., Peeters M., Van Cutsem E., Siena S. et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J. Clin. Oncol. 2008; 26 (10): 1626-34.
  13. Peeters M., Van Cutsem E., Siena S., Humblet Y., Alain Hendlisz A. et al. A Phase 3, multicenter, randomized controlled trial of panitumumab plus best supportive care (BSC) vs. BSC alone in patients with metastatic colorectal cancer. Proc. Am. Assoc. Cancer Res. 2006; 47: A CP-1, abstr.
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