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Prozherin S.V.

Sverdlovsk Oblast Center for Prevention and Control of AIDS

Podymova A.S.

Sverdlovsk Regional Center for Prevention and Control of AIDS

Anogenital warts in HIV-positive patients

Authors:

Prozherin S.V., Podymova A.S.

More about the authors

Journal: Russian Journal of Clinical Dermatology and Venereology. 2022;21(1): 128‑137

DOI: 10.17116/klinderma202221011128

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Table of contents

ANOGENITAL WARTS IN HIV-POSITIVE PATIENTS
ANOGENITAL WARTS IN HIV-POSITIVE PATIENTS

To cite this article:

Prozherin SV, Podymova AS. Anogenital warts in HIV-positive patients. Russian Journal of Clinical Dermatology and Venereology. 2022;21(1):128‑137. (In Russ.)
https://doi.org/10.17116/klinderma202221011128

Подписка 2026 Клиническая дерматология и венерология (Russian Journal of Clinical Dermatology and Venereology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Anogenital warts (AGW) are common in people living with HIV (PLHIV). The progression of HIV infection, accompanied by a decrease in CD4+ T-lymphocytes and an increase in plasma HIV RNA concentration, contributes to the manifestation of AGW.Co-infection with HPV of high carcinogenic risk in AGW is more common in PLHIV than in HIV-negative patients.Previous studies demonstrated a significantly higher incidence of AGW among HIV-positive patients compared to people without HIV. Also, the risk of human immunodeficiency virus infection in HPV-infected patients is 1.9-fold higher. The article presents data on the trends of AGW and HIV incidence in the Russian Federation in 2000–2018. The clinical manifestations and course of AGW in HIV-infected patients are considered, and possible therapeutic approaches based on the HIV status of patients are described. A review of the evidence on the antiretroviral therapy’s impact on the clinical course and incidence of AGW among PLHIV is presented. There are limited data on the results of the systemic drugs therapy for refractory AGW in patients with HIV infection. The efficacy and safety of gender-neutral HPV vaccination with quadrivalent or 9-valent vaccines in HIV-infected patients are discussed.

Keywords:

human papillomavirus
anogenital warts
HIV infection
people living with HIV

Authors:

Prozherin S.V.

Sverdlovsk Oblast Center for Prevention and Control of AIDS

Podymova A.S.

Sverdlovsk Regional Center for Prevention and Control of AIDS

Received:

03.02.2021

Accepted:

30.12.2021

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