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Svechnikova E.V.

Novosibirsk State Medical University

Marshani Z.B.

Polyclinic No. 1 of Administrative Directorate of the President of the Russian Federation

Fomin K.A.

Polyclinic No. 1 of Administrative Directorate of the President of the Russian Federation;
Vladimirsky Moscow Regional Research Clinical Institute

Evdokimov E.Yu.

Polyclinic No. 1 of Administrative Directorate of the President of the Russian Federation;
Central Research Institute of Epidemiology

New coronavirus infection in the aspect of psoriasis

Authors:

Svechnikova E.V., Marshani Z.B., Fomin K.A., Evdokimov E.Yu.

More about the authors

Journal: Russian Journal of Clinical Dermatology and Venereology. 2021;20(3): 77‑84

DOI: 10.17116/klinderma20212003177

Read: 2390 times

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Table of contents

NEW CORONAVIRUS INFECTION IN THE ASPECT OF PSORIASIS
NEW CORONAVIRUS INFECTION IN THE ASPECT OF PSORIASIS

To cite this article:

Svechnikova EV, Marshani ZB, Fomin KA, Evdokimov EYu. New coronavirus infection in the aspect of psoriasis. Russian Journal of Clinical Dermatology and Venereology. 2021;20(3):77‑84. (In Russ.)
https://doi.org/10.17116/klinderma20212003177

Подписка 2026 Клиническая дерматология и венерология (Russian Journal of Clinical Dermatology and Venereology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

In a relatively short period of its existence, the new coronavirus has had a huge impact on the health care system and social infrastructure around the world. Despite the fact that majority of those infected have an asymptomatic or mild course of the disease, in a number of patients the infection becomes threatening and can lead to death. Among the risk factors for an unfavorable outcome, senior age, the presence of comorbidities and, presumably, immunosuppression were identified. This situation also affect the dermatological practice where a number of patients need long-term immunosuppressive therapy. Patients with psoriasis receiving genetically engineered biological drugs (GEBDs) make up a significant proportion of this cohort and discontinuation of treatment can lead to negative consequences. The accumulated knowledge suggests that usage of certain GEBD does not increase the risks of COVID-19 but also can beneficially affect the underlying cytokine storm. Thus, during a pandemic the dermatologists all over the world were faced with the question of the possibility and feasibility of continuing the use of GEBD in patients with psoriasis. The characteristics of the coronavirus, the pathogenesis, clinical manifestations and diagnostics of COVID-19 are presented, and data on the possibility of continuing genetically engineered therapy in patients with psoriasis are considered. In addition, the article presents own observations of the new coronavirus infection in patients with psoriasis based on GEBD.

Keywords:

SARS-CoV-2
COVID-19
psoriasis
genetically engineered biological drugs
IL-17 inhibitor

Authors:

Svechnikova E.V.

Novosibirsk State Medical University

Marshani Z.B.

Polyclinic No. 1 of Administrative Directorate of the President of the Russian Federation

Fomin K.A.

Polyclinic No. 1 of Administrative Directorate of the President of the Russian Federation;
Vladimirsky Moscow Regional Research Clinical Institute

Evdokimov E.Yu.

Polyclinic No. 1 of Administrative Directorate of the President of the Russian Federation;
Central Research Institute of Epidemiology

Received:

03.03.2021

Accepted:

16.04.2021

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