Three-dimensional optical coherence tomography: possibilities in assessing the microvasculature of the skin

Petrova K.S.; Potekaev N.N.; Nemirova S.V.; Petrova G.A.; Karpenko A.A.

doi:https://doi.org/10.17116/klinderma202019031356

Petrova K.S.

Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation

Potekaev N.N.

Moscow Scientific and Practical Center of Dermatovenerology and Cosmetology;
The Russian National Research Medical University named after N.I. Pirogov

ORCID: 0000-0002-9578-5490

Nemirova S.V.

Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation

Petrova G.A.

Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation

Karpenko A.A.

Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation

ORCID: 0000-0001-6914-334X

Three-dimensional optical coherence tomography: possibilities in assessing the microvasculature of the skin

Authors:

Petrova K.S., Potekaev N.N., Nemirova S.V., Petrova G.A., Karpenko A.A.

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Journal: Russian Journal of Clinical Dermatology and Venereology. 2020;19(3): 356‑365

DOI: 10.17116/klinderma202019031356

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To cite this article:

Petrova KS, Potekaev NN, Nemirova SV, Petrova GA, Karpenko AA. Three-dimensional optical coherence tomography: possibilities in assessing the microvasculature of the skin. Russian Journal of Clinical Dermatology and Venereology. 2020;19(3):356‑365. (In Russ.)
https://doi.org/10.17116/klinderma202019031356

Подписка 2026 Клиническая дерматология и венерология (Russian Journal of Clinical Dermatology and Venereology)

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INTRODUCTION

In the absence of traumatic, effective and affordable methods for an objective assessment of the microvasculature of the skin, the mechanisms of development of many dermatoses and systemic diseases, accompanied by pronounced changes in the microvasculature of the skin, remain poorly investigate.

THE PURPOSE OF THE STUDY

Is to describe the morphological characteristics of the skin and its microvasculature, determined by the method of optical coherence tomography (OCT), in normal conditions and in patients with angiopathies.

MATERIAL AND METHODS

An optical coherent tomograph was used for a non-invasive study of the internal structure of human surface tissues (developed by «BIOMEDTECH» LLC), equipped with a specialized probe for studying external biological tissues with 3D modeling of optical «sections». The study involved 13 healthy volunteers, 36 patients with chronic venous, 28 with chronic arterial insufficiency, 3 with polymorphic dermal angiitis, 6 with Raynaud’s syndrome, 1 with the vena cava superior syndrome and 1 with a diagnosis of “port-wine stain”.

RESULTS

Described specific OCT characteristics of the bloodstream of the skin and its condition as a whole in patients with chronic venous and arterial insufficiency, Raynaud’s syndrome, dermal angiitis, vena cava superior syndrome and port-wine stain in comparison with the skin of a healthy person. Represented diagnostic criteria that allow to diagnose these conditions using OCT.

Keywords:

chronic arterial insufficiency

chronic venous insufficiency

optical coherence tomography

microvasculature of the skin

Authors:

Petrova K.S.

Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation

Potekaev N.N.

Moscow Scientific and Practical Center of Dermatovenerology and Cosmetology;
The Russian National Research Medical University named after N.I. Pirogov

ORCID: 0000-0002-9578-5490

Nemirova S.V.

Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation

Petrova G.A.

Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation

Karpenko A.A.

Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation

ORCID: 0000-0001-6914-334X

Received:

20.11.2019

Accepted:

10.04.2020

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