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Rybkina V.L.

Southern Ural Biophysics Institute of the Federal Medical Biological Agency of Russia, Ozersk, Chelyabinsk region, Russia

Azizova T.V.

Southern Ural Biophysics Institute of the Federal Medical Biological Agency of Russia, Ozersk, Chelyabinsk region, Russia

Adamova G.V.

Southern Ural Biophysics Institute of the Federal Medical Biological Agency of Russia, Ozersk, Chelyabinsk region, Russia

Risk factors of malignant neoplasms of the skin

Authors:

Rybkina V.L., Azizova T.V., Adamova G.V.

More about the authors

Journal: Russian Journal of Clinical Dermatology and Venereology. 2019;18(5): 548‑555

DOI: 10.17116/klinderma201918051548

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To cite this article:

Rybkina VL, Azizova TV, Adamova GV. Risk factors of malignant neoplasms of the skin. Russian Journal of Clinical Dermatology and Venereology. 2019;18(5):548‑555. (In Russ.)
https://doi.org/10.17116/klinderma201918051548

 
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Literature sources were found in databases MEDLINE in search systems PubMed, Cyberleninka, elibrary.ru using terms «risk factors», «skin melanoma», «basal cell carcinoma of the skin», «squamous cell carcinoma of the skin» In this review we used full text literature sources in Russian and English. Meta-analyzes were preferred. Search for literature was finished in March of 2018. Inclusion factors were data on risk factors of malignant skin neoplasms (MSN), on relative risk, odds ratio, standardized coefficients of morbidity and mortality. We used the results of cohort and case-control studies. Article abstracts were excluded. This review is dedicated to the analysis of risk factors of malignant skin neoplasms. Gender, age, genetic factors, pigment characteristics, number of nevi, actinic skin damage, obesity, women endocrine status, solar radiation, ultraviolet exposure from artificial sources, ultraviolet exposure during airplane flights, ionizing radiation exposure, drinks and food, connection of MSN with other conditions, medications, other risk factors. Results of multiple studies dedicated to risk factors of skin melanoma and non-melanoma skin cancers suggest the most important role of genetic factors (especially those which are associated with pigment characteristics of the skin) in the development of such MSN. UV exposure is the primary external risk factor of MSN of the skin.

Keywords:

risk factors
skin melanoma
basal cell carcinoma of the skin
squamous cell carcinoma of the skin

Authors:

Rybkina V.L.

Southern Ural Biophysics Institute of the Federal Medical Biological Agency of Russia, Ozersk, Chelyabinsk region, Russia

Azizova T.V.

Southern Ural Biophysics Institute of the Federal Medical Biological Agency of Russia, Ozersk, Chelyabinsk region, Russia

Adamova G.V.

Southern Ural Biophysics Institute of the Federal Medical Biological Agency of Russia, Ozersk, Chelyabinsk region, Russia

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