The results of studying the features of microcirculation in facial skin in women during different age periods using laser Doppler flowmetry. Objective. To study the features of microcirculation in facial skin in women during different age periods using laser Doppler flowmetry and to reveal the dependence of microcirculatory alterations on duration of the menopausal stage. Material and methods. 106 women were examined. The groups were formed depending on duration of the menopausal stage. Microcirculation and saturation of facial skin was studied using a LAKK-M laser analyzer of the velocity of surface capillary blood flow. Results. Tissue perfusion (PU - a measurement unit of tissue perfusion) in groups 1 and 2 of women with different duration of the menopausal stage was significantly higher (p<0.01) than that in the control group: 12.3±2.3, 12.9±2.7 and 10.9±3.2, respectively. The indicator of tissue perfusion surgical in women with surgical menopause was significantly higher (p<0.01) than that in women at the pre- and post-menopausal stage and differed from that in the control group (13.8±1.3, 12.4±0.8 and 10.8±0.5 PU, respectively). Hemoglobin oxygen saturation was reliably higher (p<0.01) in women experiencing surgical menopause (86.7±0.2). Conclusions. Laser Doppler flowmetry in dermato-cosmetology allows one to control dynamic changes in facial skin microvessels. The modern noninvasive informative methods can be used to elaborate the protocol for correcting involutive facial skin changes in women experiencing menopause regardless of its duration.