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Podobed A.V.

Alexandrov National Cancer Center of Belarus

Topolnitskiy E.B.

Siberian State Medical University;
Tomsk Regional Clinical Hospital;
National Research Tomsk State University

Shefer N.A.

Siberian State Medical University;
Tomsk Regional Clinical Hospital

Savchenko O.G.

Alexandrov National Cancer Center of Belarus

Fesenko S.V.

Siberian State Medical University

Usoltseva S.V.

Siberian State Medical University;
Tomsk Regional Clinical Hospital

Immediate results of thoracoscopic and open combined thymectomy: a two-center study

Authors:

Podobed A.V., Topolnitskiy E.B., Shefer N.A., Savchenko O.G., Fesenko S.V., Usoltseva S.V.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2025;(5): 58‑64

DOI: 10.17116/hirurgia202505158

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Table of contents

IMMEDIATE RESULTS OF THORACOSCOPIC AND OPEN COMBINED THYMECTOMY: A TWO-CENTER STUDY
IMMEDIATE RESULTS OF THORACOSCOPIC AND OPEN COMBINED THYMECTOMY: A TWO-CENTER STUDY

To cite this article:

Podobed AV, Topolnitskiy EB, Shefer NA, Savchenko OG, Fesenko SV, Usoltseva SV. Immediate results of thoracoscopic and open combined thymectomy: a two-center study. Pirogov Russian Journal of Surgery. 2025;(5):58‑64. (In Russ.)
https://doi.org/10.17116/hirurgia202505158

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

To analyze the immediate results of thoracoscopic (video-assisted thoracoscopic thymectomy — VATS TE) and open combined thymectomy (OTE) for invasive thymomas.

MATERIAL AND METHODS

We retrospectively analyzed 64 patients with locally advanced thymus tumors who underwent surgical treatment in two specialized centers. Combined VATS TE (main group) was performed in 28 patients, OTE (control group) — in 45 patients. Immediate results of these interventions were estimated.

RESULTS

Surgery time was similar in both groups. VATS TE was associated with lower intraoperative blood loss (p<0.001), complication rate (p=0.011), duration of postoperative pleural drainage (p<0.001), ICU stay (p<0.001) and hospital stay (p=0.023). There was lower need for narcotic analgesics (p=0.039) and duration of regular pain medication intake (p<0.001).

CONCLUSION

Combined VATS TE is possible in certain patients with locally advanced thymus tumors and characterized by better immediate results compared to OTE. However, analysis of long-term results is necessary to determine the feasibility of combined VATS TE.

Keywords:

thymoma
myasthenia
thoracoscopic thymectomy
combined thymectomy
sternotomy

Authors:

Podobed A.V.

Alexandrov National Cancer Center of Belarus

Topolnitskiy E.B.

Siberian State Medical University;
Tomsk Regional Clinical Hospital;
National Research Tomsk State University

Shefer N.A.

Siberian State Medical University;
Tomsk Regional Clinical Hospital

Savchenko O.G.

Alexandrov National Cancer Center of Belarus

Fesenko S.V.

Siberian State Medical University

Usoltseva S.V.

Siberian State Medical University;
Tomsk Regional Clinical Hospital

Received:

01.10.2024

Accepted:

05.02.2024

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