Factors associated with normal leukocyte count and C-reactive protein in adults with acute appendicitis: a retrospective cohort study

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OBJECTIVE

To identify the factors associated with normal leukocyte count and C-reactive protein (CRP) in adults with acute appendicitis.

MATERIAL AND METHODS

A retrospective cohort study included patients aged 18-60 years after surgeries for acute appendicitis. Convenience sampling was used to select medical records, and variables such as age, sex, weight, height, origin, self-medication, diabetes (DM2), high blood pressure (HBP), type of appendicitis, duration of illness, preoperative time, type of appendectomy, operative time, and hospital stay were analyzed. Patients were categorized into those with normal and abnormal inflammatory parameters. The SPSS version 28 software was used for analysis.

RESULTS

We included 333 patients; 11.11% ones had normal inflammatory parameters. Both groups had mean age of approximately 33 years. Men comprised 56.76% and 57.43%in both groups, respectively. The abnormal group had shorter mean preoperative time, and catarrhal appendicitis was more common in the normal group. Multivariate analysis revealed that rural origin and self-medication were significantly associated with normal inflammatory parameters.

CONCLUSION

The prevalence of normal inflammatory parameters in acute appendicitis patients was 11.11%. Rural origin, self-medication, shorter preoperative time, and catarrhal appendicitis were significantly associated with normal inflammatory parameters in this context.

Keywords:

acute appendicitis

white blood cells

CRP

inflammatory parameters

Authors:

Yamir C.S.

Antenor Orrego Private University

Caballero-Alvarado J.

Antenor Orrego Private University;
Regional Hospital of Trujillo

ORCID: 0000-0001-8297-6901

Lozano-Peralta K.

Antenor Orrego Private University

Zavaleta-Corvera C.

Antenor Orrego Private University

ORCID: 0000-0001-5918-8261

Received:

12.11.2023

Accepted:

12.12.2023

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