Indocyanine green in liver tumor resection

Kaprin A.D.; Ivanov S.A.; Petrov L.O.; Isaeva A.G.

doi:https://doi.org/10.17116/hirurgia20230925

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Abstract:

Primary liver cancer and colorectal cancer liver metastases are among the leading causes of cancer-related mortality worldwide. Surgery is one of the main methods of treatment to achieve the best results in overall and recurrence-free survival. The main objectives in this surgery are preoperative planning, assessment of functional viability of liver parenchyma and total resection with low complication rate. Post-resection liver failure is one of the most formidable and often fatal complication following functional failure of liver remnant. Thus, preoperative assessment of liver functional reserves is a necessary step for adequate selection of patients and safe surgery. Passive liver tests, such as biochemical parameters or clinical scales, do not accurately reflect the actual functional component of liver parenchyma. The most accurate method is dynamic quantitative test of liver, such as indocyanine green clearance. The authors discuss the practical aspects of preoperative assessment of liver functional reserves using indocyanine green, as well as the concept and technical foundations of fluorescent imaging in hepatobiliary surgery.

Keywords:

post-resection liver failure

liver resection

liver function tests

ICG test

indocyanine green

Authors:

Kaprin A.D.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of Ministry of Russia;
Peoples’ Friendship University of Russia

SPIN RSCI: 1759-8101
Scopus AuthorID: 6602709853
ResearcherID: K-1445-2014
ORCID: 0000-0001-8784-8415

Ivanov S.A.

Tsyb Medical Radiology Research Center

ORCID: 0000-0001-7689-6032

Petrov L.O.

National Medical Research Center for Radiology

ORCID: 0000-0001-6272-9647

Isaeva A.G.

Tsyb Medical Radiology Research Center

ORCID: 0000-0002-3038-5904

Received:

05.06.2023

Accepted:

07.07.2023

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References:

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