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Alekseev M.V.

National Medical Research Centre for Coloproctology named after A.N Ryzhikh

Shelygin Y.A.

Ryzhikh National Medical Research Centre for Coloproctology;
Russian Medical Academy of Continuous Professional Education

Rybakov E.G.

Ryzhikh National Medical Research Centre of Coloproctology

Risk factors associated with non-closure of defunctioning stoma in patients with rectal cancer: univariate and multivariate analysis

Authors:

Alekseev M.V., Shelygin Y.A., Rybakov E.G.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2021;(2): 40‑47

DOI: 10.17116/hirurgia202102140

Read: 7557 times

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Table of contents

RISK FACTORS ASSOCIATED WITH NON-CLOSURE OF DEFUNCTIONING STOMA IN PATIENTS WITH RECTAL CANCER: UNIVARIATE AND MULTIVARIATE ANALYSIS
RISK FACTORS ASSOCIATED WITH NON-CLOSURE OF DEFUNCTIONING STOMA IN PATIENTS WITH RECTAL CANCER: UNIVARIATE AND MULTIVARIATE ANALYSIS

To cite this article:

Alekseev MV, Shelygin YA, Rybakov EG. Risk factors associated with non-closure of defunctioning stoma in patients with rectal cancer: univariate and multivariate analysis. Pirogov Russian Journal of Surgery. 2021;(2):40‑47. (In Russ.)
https://doi.org/10.17116/hirurgia202102140

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

To identify the risk factors associated with non-closure of defunctioning stoma in patients with rectal cancer.

MATERIAL AND METHODS

A retrospective analysis included patients who underwent surgical treatment at the Ryzhikh National Medical Research Centre of Coloproctology for the period from March 2017 to August 2019. Inclusion criterion was anterior or low anterior resection followed by anastomosis and preventive stoma. Univariate and multivariate analysis enrolled 28 factors for identifying the risk factors of non-closure of defunctioning stoma.

RESULTS

There were 246 patients with rectal cancer. Intraoperative fluorescence angiography was applied in 145 cases to assess blood supply within the anastomosis and reduce the risk of anastomotic leakage. According to multivariate analysis, only two factors had significant influence on non-closure of preventive stoma — any grade of anastomotic leakage (OR 6.5; 95% CI 2.2—18.8, p=0.001) and rectal cancer stage IV (OR 7.2; 95% CI 1.9—27.6, p=0.004).

CONCLUSION

According to our data, permanent stoma is observed in 15% of patients.

Keywords:

anastomosis leakage
fluorescence angiography
defunctioning stoma
risk factors

Authors:

Alekseev M.V.

National Medical Research Centre for Coloproctology named after A.N Ryzhikh

Shelygin Y.A.

Ryzhikh National Medical Research Centre for Coloproctology;
Russian Medical Academy of Continuous Professional Education

Rybakov E.G.

Ryzhikh National Medical Research Centre of Coloproctology

Received:

13.03.2020

Accepted:

21.04.2020

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