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Filin A.V.

Petrovsky National Research Centre of Surgery

Kim E.F.

Moscow City Cancer Hospital No. 62

Charchyan E.R.

Petrovsky National Research Centre of Surgery

Metelin A.V.

Petrovsky National Research Centre of Surgery

Dymova O.V.

Petrovsky National Research Centre of Surgery

Kachanov D.Yu.

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology

Moiseenko R.A.

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology

Khovrin V.V.

Petrovsky National Research Center of Surgery

Kryzhanovskaya E.Yu.

Petrovsky National Research Centre of Surgery

Kazakova O.V.

Petrovsky National Research Centre of Surgery

Ryabov A.B.

Hertsen Moscow Oncology Research Institute

Bazarov D.V.

Petrovsky National Research Centre of Surgery

Liver transplantation for hepatoblastoma in children

Authors:

Filin A.V., Kim E.F., Charchyan E.R., Metelin A.V., Dymova O.V., Kachanov D.Yu., Moiseenko R.A., Khovrin V.V., Kryzhanovskaya E.Yu., Kazakova O.V., Ryabov A.B., Bazarov D.V.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2020;(11): 5‑13

DOI: 10.17116/hirurgia20201115

Read: 3310 times

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Table of contents

LIVER TRANSPLANTATION FOR HEPATOBLASTOMA IN CHILDREN
LIVER TRANSPLANTATION FOR HEPATOBLASTOMA IN CHILDREN

To cite this article:

Filin AV, Kim EF, Charchyan ER, et al. . Liver transplantation for hepatoblastoma in children. Pirogov Russian Journal of Surgery. 2020;(11):5‑13. (In Russ.)
https://doi.org/10.17116/hirurgia20201115

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

To improve the outcomes in children with hepatoblastoma.

MATERIAL AND METHODS

There were 160 children with focal liver lesions who underwent surgery at the department of liver transplantation in 2008—2019. Patients with malignant tumors made up 77% (n=123). Hepatoblastoma (HB) prevailed (86%, n=106). Liver transplantation was performed in 19 (18%) patients with HB. Median follow-up after transplantation was 24.3 months by December 2019. Follow-up period did not exceed 4 years in more than 2/3 of patients.

RESULTS

Overall and disease-free 10-year survival was 87.1% and 82.7%, respectively. Similar values were observed after resections (91.1% and 86.6%). At the same time, actuarial 4-year survival after liver transplantation for HB was 68%.

CONCLUSION

Improvement of treatment outcomes may be achieved through multidisciplinary interaction ensuring timely drug therapy and liver transplantation.

Keywords:

liver transplantation
hepatoblastoma
liver tumors
liver resection

Authors:

Filin A.V.

Petrovsky National Research Centre of Surgery

Kim E.F.

Moscow City Cancer Hospital No. 62

Charchyan E.R.

Petrovsky National Research Centre of Surgery

Metelin A.V.

Petrovsky National Research Centre of Surgery

Dymova O.V.

Petrovsky National Research Centre of Surgery

Kachanov D.Yu.

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology

Moiseenko R.A.

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology

Khovrin V.V.

Petrovsky National Research Center of Surgery

Kryzhanovskaya E.Yu.

Petrovsky National Research Centre of Surgery

Kazakova O.V.

Petrovsky National Research Centre of Surgery

Ryabov A.B.

Hertsen Moscow Oncology Research Institute

Bazarov D.V.

Petrovsky National Research Centre of Surgery

Received:

16.03.2020

Accepted:

03.04.2020

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References:

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