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Mezenova T.V.

Russian Academy of Postgraduate Education, Moscow, Russia

Forced osteoarthritis therapy: expanding the scope of the possible

Authors:

Mezenova T.V.

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Journal: Pirogov Russian Journal of Surgery. 2018;(5): 91‑95

DOI: 10.17116/hirurgia2018591-95

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FORCED OSTEOARTHRITIS THERAPY: EXPANDING THE SCOPE OF THE POSSIBLE
FORCED OSTEOARTHRITIS THERAPY: EXPANDING THE SCOPE OF THE POSSIBLE

To cite this article:

Mezenova TV. Forced osteoarthritis therapy: expanding the scope of the possible. Pirogov Russian Journal of Surgery. 2018;(5):91‑95. (In Russ.)
https://doi.org/10.17116/hirurgia2018591-95

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The article deals the modern concepts of the mechanism of pain in osteoarthritis. It was established that synovial inflammation and immune disorders play an important role in the pathogenesis of pain in osteoarthritis. Hyperproduction of pro-inflammatory cytokines supports inflammation and degradation of cartilaginous tissue in osteoarthritis. The mechanisms of pathogenetic action of chondroitin sulfate are disclosed, and the evidence base of its preclinical and clinical studies in the treatment of osteoarthritis is presented. The data of clinical application of the Mucosat — pharmaceutical substance chondroitin sulfate in the form of a ready-made dosage form for intramuscular injection are presented. The practical advantages of including SYSADOA in complex therapy of osteoarthritis are discussed.

Keywords:

osteoarthritis
pain
proinflammatory cytokines
chondroprotectors
chondroitin sulfate
Mucosat

Authors:

Mezenova T.V.

Russian Academy of Postgraduate Education, Moscow, Russia

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References:

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