The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 101-59-87
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2024
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Enginoev S.T.

Federal Center for Cardiovascular Surgery;
Astrakhan State Medical University

Chernov I.I.

Federal Center for Cardiovascular Surgery

Komarov R.N.

Sechenov First Moscow State Medical University

Belov V.A.

Sukhanov Federal Center for Cardiovascular Surgery

Gamzaev A.B.

Privolzhsky Research Medical University

Arutyunyan V.B.

Sukhanov Federal Center for Cardiovascular Surgery

Kadyraliev B.K.

Sukhanov Federal Center for Cardiovascular Surgery;
Perm National Research Polytechnic University

Semagin A.P.

Samara Regional Clinical Cardiology Dispensary

Ismailbaev A.M.

Sechenov First Moscow State Medical University

Kuznetsov D.V.

Samara Regional Clinical Cardiology Dispensary

Zybin A.A.

Samara Regional Clinical Cardiology Dispensary

Pashaeva A.R.

Astrakhan State Medical University

Tlisov B.M.

Sechenov First Moscow State Medical University

Three-year results of aortic valve neocuspidization (Ozaki procedure): a multiple-center retrospective study

Authors:

Enginoev S.T., Chernov I.I., Komarov R.N., Belov V.A., Gamzaev A.B., Arutyunyan V.B., Kadyraliev B.K., Semagin A.P., Ismailbaev A.M., Kuznetsov D.V., Zybin A.A., Pashaeva A.R., Tlisov B.M.

More about the authors

Journal: Russian Journal of Cardiology and Cardiovascular Surgery. 2024;17(4): 428‑435

DOI: 10.17116/kardio202417041428

Views: 293

Downloaded: 9

Buy for 200₽
Contact the author
Table of contents

To cite this article:

Enginoev ST, Chernov II, Komarov RN, et al. . Three-year results of aortic valve neocuspidization (Ozaki procedure): a multiple-center retrospective study. Russian Journal of Cardiology and Cardiovascular Surgery. 2024;17(4):428‑435. (In Russ.)
https://doi.org/10.17116/kardio202417041428

Подписка 2025 (Russian Journal of Cardiology and Cardiovascular Surgery)
 
МСФ на ЯМ
Close metadata

OBJECTIVE

To analyze 3-year outcomes after Ozaki procedure.

MATERIAL AND METHODS

A retrospective multiple-center study included 251 patients with aortic valve disease between January 2017 and February 2020.

RESULTS

The main indication for surgery was severe aortic stenosis in 230 (91.6%) cases, bicuspid aortic valve in 88 (35%) cases, aortic regurgitation (AR) in 21 (8.4%) cases and infective endocarditis (IE) in 12 (4.8%) cases. The sample included 116 (46.2%) men and 135 (53.8%) women (mean age 66 (60—70) years). There were no conversions of the Ozaki procedure to aortic valve replacement with biological or mechanical prostheses. Xenopericardium was used in 7 cases due to redo surgeries. Combined interventions were performed in 103 (42.2%) patients. In-hospital mortality was 1.2%. Two (0.8%) patients underwent redo sternotomy for bleeding. Follow-up was completed in all patients (median period 24 (17—32) months). Three-year survival and freedom from redo surgeries were 90.6% and 94.6%, respectively. Postoperative echocardiography revealed mean pressure gradient 6 mm Hg. AR ≥2 was detected in 13 (8.3%) patients in 22.6±9.9 months after surgery. Baseline IE (p=0.04) and AR ≥2 (p=0.006) at discharge are significant predictors of aortic valve dysfunction after Ozaki surgery.

CONCLUSION

The Ozaki procedure in patients with aortic valve disease has favorable immediate results regarding in-hospital mortality and postoperative morbidity, as well as optimal intermediate results regarding survival, freedom from redo surgeries and hemodynamic parameters. Further monitoring of patients is necessary to assess the long-term results after this procedure.

Keywords:

aortic valve neocuspidization
aortic valve
Ozaki procedure

Authors:

Enginoev S.T.

Federal Center for Cardiovascular Surgery;
Astrakhan State Medical University

Chernov I.I.

Federal Center for Cardiovascular Surgery

Komarov R.N.

Sechenov First Moscow State Medical University

Belov V.A.

Sukhanov Federal Center for Cardiovascular Surgery

Gamzaev A.B.

Privolzhsky Research Medical University

Arutyunyan V.B.

Sukhanov Federal Center for Cardiovascular Surgery

Kadyraliev B.K.

Sukhanov Federal Center for Cardiovascular Surgery;
Perm National Research Polytechnic University

Semagin A.P.

Samara Regional Clinical Cardiology Dispensary

Ismailbaev A.M.

Sechenov First Moscow State Medical University

Kuznetsov D.V.

Samara Regional Clinical Cardiology Dispensary

Zybin A.A.

Samara Regional Clinical Cardiology Dispensary

Pashaeva A.R.

Astrakhan State Medical University

Tlisov B.M.

Sechenov First Moscow State Medical University

Received:

31.03.2023

Accepted:

27.04.2023

List of references:

  1. Ozaki S, Kawase I, Yamashita H, Uchida S, Nozawa Y, Matsuyama T, et al. Aortic valve reconstruction using self-developed aortic valve plasty system in aortic valve disease. Interact Cardiovasc Thorac Surg. 2011;12:550-553.  https://doi.org/10.1510/icvts.2010.253682
  2. Ozaki S, Kawase I, Yamashita H, Uchida S, Nozawa Y, Takatoh M, et al. A total of 404 cases of aortic valve reconstruction with glutaraldehyde-treated autologous pericardium. J Thorac Cardiovasc Surg. 2014;147:301-306.  https://doi.org/10.1016/j.jtcvs.2012.11.012
  3. Ngo HT, Nguyen TT, Nguyen HC, Camilleri L, Thanh LN, Doan HQ. Bicuspid reconstruction surgery in a patient suffering from aortic valve infective endocarditis with annular abscess using Ozaki’s procedure: A case report. Int J Surg Case Rep. 2020;76:266-269.  https://doi.org/10.1016/j.ijscr.2020.09.197
  4. Nkomo VT, Gardin JM, Skelton TN, Gottdiener JS, Scott CG, Enriquez-Sarano M. Burden of valvular heart diseases: a population-based study. Lancet. 2006;368:1005-1011.
  5. Di Eusanio M, Fortuna D, De Palma R, Dell’Amore A, Lamarra M, Contini GA, et al. Aortic valve replacement: results and predictors of mortality from a contemporary series of 2256 patients. J Thorac Cardiovasc Surg. 2011;141:940-947.  https://doi.org/10.1016/j.jtcvs.2010.05.044
  6. Baumgartner H, Falk V, Bax JJ, De Bonis M, Hamm C, Holm PJ, et al. 2017 ESC/EACTS Guidelines for the management of valvular heart disease. vol. 38. 2017. https://doi.org/10.1093/eurheartj/ehx391
  7. Otto CM, Nishimura RA, Bonow RO, Krieger EV, Mack M, Mcleod C, et al. 2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease. J Am Coll Cardiol. 2021. https://doi.org/10.1016/j.jacc.2020.11.018
  8. Kostyunin AE, Yuzhalin AE, Rezvova MA, Ovcharenko EA, Glushkova TV, Kutikhin AG. Degeneration of Bioprosthetic Heart Valves: Update 2020. J Am Heart Assoc. 2020;9:e018506. https://doi.org/10.1161/JAHA.120.018506
  9. Sá MPBO, Perazzo ÁM, Zhigalov K, Komarov R, Kadyraliev B, Enginoev S, et al. Aortic valve neocuspidization with glutaraldehyde-treated autologous pericardium (Ozaki procedure) — a promising surgical technique. Brazilian J Cardiovasc Surg. 2019;34.  https://doi.org/10.21470/1678-9741-2019-0304
  10. Chernov II, Enginoev ST, Komarov RN, Bazylev VV, Tarasov DG, et al. Short-term outcomes of Ozaki procedure: a multicenter study. Russian Journal of Cardiology. 2020;25(S4):4157. (In Russ.). https://doi.org/10.15829/1560-4071-2020-4157
  11. Ozaki S, Kawase I, Yamashita H, Uchida S, Takatoh M, Kiyohara N. Midterm outcomes after aortic valve neocuspidization with glutaraldehyde-treated autologous pericardium. J Thorac Cardiovasc Surg. 2018;155:2379-2387. https://doi.org/10.1016/j.jtcvs.2018.01.087
  12. Lancellotti P, Pibarot P, Chambers J, Edvardsen T, Delgado V, Dulgheru R, et al. Recommendations for the imaging assessment of prosthetic heart valves: a report from the European Association of Cardiovascular Imaging endorsed by the Chinese Society of Echocardiography, the Inter-American Society of Echocardiography, and the Brazilian. Eur Hear J Cardiovasc Imaging. 2016;17:589-590.  https://doi.org/10.1093/ehjci/jew025
  13. Sá MP, Chernov I., Marchenko A., Chagyan V., Komarov R., Askadinov M., et al. Aortic Valve Neocuspidization (Ozaki Procedure) in Patients with Small Aortic Annulus (≤21 mm): A Multicenter Study. Struct. Hear. 2020. https://doi.org/10.1080/24748706.2020.1792595
  14. Dvir D, Bourguignon T, Otto CM, Hahn RT, Rosenhek R, Webb JG, et al. Standardized Definition of Structural Valve Degeneration for Surgical and Transcatheter Bioprosthetic Aortic Valves. Circulation. 2018;137:388-399.  https://doi.org/10.1161/CIRCULATIONAHA.117.030729
  15. Takahashi H, Kadowaki T, Maruo A, Yutaka O, Oshima Y. Mid-term results of mitral valve repair with autologous pericardium in pediatric patients. J Heart Valve Dis. 2014;23:302-309. 
  16. Amabile A, Krane M, Dufendach K, Baird CW, Ganjoo N, Eckstein FS, et al. Standardized Aortic Valve Neocuspidization for Treatment of Aortic Valve Diseases. Ann Thorac Surg. 2022;1108-1117. https://doi.org/10.1016/j.athoracsur.2022.03.067
  17. Frank S, Johnson A, Ross JrJ. Natural history of valvular aortic stenosis. Br Heart J. 1973;35:41-46.  https://doi.org/10.1136/hrt.35.1.41
  18. Kang D-H, Park S-J, Lee S-A, Lee S, Kim D-H, Kim H-K, et al. Early Surgery or Conservative Care for Asymptomatic Aortic Stenosis. N Engl J Med. 2020;382:111-119.  https://doi.org/10.1056/nejmoa1912846
  19. Kahveci G, Bayrak F, Pala S, Mutlu B. Impact of bicuspid aortic valve on complications and death in infective endocarditis of native aortic valves. Texas Hear Inst J. 2009;36:111-116. 
  20. Wada T, Miyamoto S, Shibata T, Abe K, Murakami T. Early and Mid-term Results of Aortic Valve Reconstruction with Autologous Pericardium (Ozaki Procedure): A Multicenter Study in Japan Outside of Toho University. Struct. Hear. 2020;4:136-137.  https://doi.org/10.1080/24748706.2020.1715139
  21. Khatchatourov G, van Steenberghe M, Goy D, Potin M, Orrit J, Perret F, et al. Short-term outcomes of aortic valve neocuspidization for various aortic valve diseases. JTCVS Open. 2021;8:193-202.  https://doi.org/10.1016/j.xjon.2021.08.027
  22. Mylonas KS, Tasoudis PT, Pavlopoulos D, Kanakis M, Stavridis GT, Avgerinos DV. Aortic valve neocuspidization using the Ozaki technique: A meta-analysis of reconstructed patient-level data. Am Heart J. 2023;255:1-11.  https://doi.org/10.1016/j.ahj.2022.09.003
  23. Pibarot P, Dumesnil JG. Prosthesis-patient mismatch: Definition, clinical impact, and prevention. Heart. 2006;92:1022-1029. https://doi.org/10.1136/hrt.2005.067363
  24. Mitrev Z, Risteski P, Todorovska M, Pavlovikj M, Sá MPBO, Rosalia R. Aortic Valve Neocuspidization Using Xenologous Pericardium Versus Bioprosthetic Valve Replacement. Ann Thorac Surg. 2022;113:1192-1199. https://doi.org/10.1016/j.athoracsur.2021.04.099
  25. Dalmau MJ, Maríagonzález-Santos J, López-Rodríguez J, Bueno M, Arribas A. The Carpentier-Edwards Perimount Magna aortic xenograft: a new design with an improved hemodynamic performance. Interact Cardiovasc Thorac Surg. 2006;5:263-267.  https://doi.org/10.1510/icvts.2005.120352
  26. Perez de Arenaza D, Lees B, Flather M, Nugara F, Husebye T, Jasinski M, et al. Randomized comparison of stentless versus stented valves for aortic stenosis: effects on left ventricular mass. Circulation. 2005;112:2696-2702. https://doi.org/10.1161/CIRCULATIONAHA.104.521161
  27. Tasoudis PT, Varvoglis DN, Vitkos E, Mylonas KS, Sá MP, Ikonomidis JS, et al. Mechanical versus bioprosthetic valve for aortic valve replacement: systematic review and meta-analysis of reconstructed individual participant data. Eur J Cardio-Thoracic Surg Off J Eur Assoc Cardio-Thoracic Surg. 2022;62.  https://doi.org/10.1093/ejcts/ezac268

Close metadata

Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register


We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.