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Trofimov N.A.

Republican Cardiology Dispensary

Babokin V.E.

Republican Cardiology Dispensary;
Institute for Advanced Training of Physicians;
Ulyanov Chuvash State University

Egorov D.V.

Republican Cardiology Dispensary;
Ulyanov Chuvash State University

Dubova A.V.

Republican Cardiology Dispensary;
Ulyanov Chuvash State University

Nikolsky A.V.

Nizhny Novgorod Municipal Clinical Hospital No. 5

Tabaev R.G.

Republican Cardiology Dispensary

Rodionov A.L.

Republican Cardiology Dispensary

Dragunov A.G.

Republican Cardiology Dispensary

Nikolaeva O.V.

Republican Cardiology Dispensary

Zhamlikhanova S.S.

Ulyanov Chuvash State University

Treatment of myocarditis in COVID-19 patients

Authors:

Trofimov N.A., Babokin V.E., Egorov D.V., Dubova A.V., Nikolsky A.V., Tabaev R.G., Rodionov A.L., Dragunov A.G., Nikolaeva O.V., Zhamlikhanova S.S.

More about the authors

Read: 3641 times


To cite this article:

Trofimov NA, Babokin VE, Egorov DV, et al. Treatment of myocarditis in COVID-19 patients. Russian Journal of Cardiology and Cardiovascular Surgery. 2022;15(2):159‑166. (In Russ.)
https://doi.org/10.17116/kardio202215021159

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References:

  1. World Health Organization. WHO Director-General’s opening remarks at the media briefing on COVID-19 — 11 March 2020. https://www.who.int/director-general/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-COVID-19---11-march-2020
  2. World Health Organization. Estimating mortality from COVID-19.  https://www.who.int/news-room/commentaries/detail/estimating-mortality-from-COVID-19
  3. Johns Hopkins University. Coronavirus Resource Center. 2020 Apr 13. Accessed February 01, 2021. https://coronavirus.jhu.edu
  4. Fried JA, Ramasubbu K, Bhatt R, et al. The Variety of Cardiovascular Presentations of COVID-19. Circulation. 2020;141:1930-1936.
  5. Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72314 Cases From the Chinese Center for Disease Control and Prevention. JAMA. 2020;323:1239-1242.
  6. Lu Y, Wang P, Zhou T, et al. Comparison of Prevalence, Awareness, Treatment, and Control of Cardiovascular Risk Factors in China and the United States. J Am Heart Assoc. 2018;7(3):e007462.
  7. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet. 2020;395:497-506. 
  8. Hendren NS, Drazner MH, Bozkurt B, Cooper LT. Description and Proposed Management of the Acute COVID-19 Cardiovascular Syndrome. Circulation. 2020;141:1903-1914.
  9. Clerkin KJ, Fried JA, Raikhelkar J, et al. COVID-19 and Cardiovascular Disease. Circulation. 2020;141:1648-1655.
  10. Driggin E, Madhavan MV, Bikdeli B, et al. Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID-19 Pandemic. J Am Coll Cardiol. 2020;75:2352-2371.
  11. Zheng YY, Ma YT, Zhang JY, Xie X. COVID-19 and the cardiovascular system. Nat Rev Cardiol. 2020;17:259-260. 
  12. Madjid M, Safavi-Naeini P, Solomon SD, Vardeny O. Potential Effects of Coronaviruses on the Cardiovascular System: A Review. JAMA Cardiol. 2020;5:831-840. 
  13. Nishiga M, Wang DW, Han Y, Lewis DB, Wu JC. COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives. Nat Rev Cardiol. 2020;17:543-558. 
  14. Alhogbani T. Acute myocarditis associated with novel Middle east respiratory syndrome coronavirus. Ann Saudi Med. 2016;36:78-80. 
  15. Oudit GY, Kassiri Z, Jiang C, et al. SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS. Eur J Clin Investig. 2009;39:618-625. 
  16. Li SS, Cheng CW, Fu CL, et al. Left ventricular performance in patients with severe acute respiratory syndrome: A 30-day echocardiographic follow-up study. Circulation. 2003;108:1798-1803.
  17. Yu CM, Wong RS, Wu EB, et al. Cardiovascular complications of severe acute respiratory syndrome. Postgrad Med J. 2006;82: 140-144. 
  18. Wu CI, Postema PG, Arbelo E, et al. SARS-CoV-2, COVID-19 and inherited arrhythmia syndromes. Heart Rhythm. 2020;17(9): 1456-1462.
  19. Qian Z, Travanty EA, Oko L, et al. Innate immune response of human alveolar type II cells infected with severe acute respiratory syndrome-coronavirus. Am J Respir Cell Mol Biol. 2013;48:742-748. 
  20. Goulter AB, Goddard MJ, Allen JC, Clark KL. ACE2 gene expression is up-regulated in the human failing heart. BMC Med. 2004;2(19):15151696.
  21. Crackower MA, Sarao R, Oudit GY, et al. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature. 2002;417:822-828. 
  22. Oudit GY, Kassiri Z, Patel MP, et al. Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice. Cardiovasc Res. 2007;75:29-39. 
  23. Zhao X, Nicholls JM, Chen YG. Severe acute respiratory syndrome-associated coronavirus nucleocapsid protein interacts with Smad3 and modulates transforming growth factor-beta signaling. J Biol Chem. 2008;283:3272-3280.
  24. Meng X, Yang J, Dong M, et al. Regulatory T cells in cardiovascular diseases. Nat Rev Cardiol. 2016;13:167-179. 
  25. Qin C, Zhou L, Hu Z, et al. Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China. Clin Infect Dis. 2020;71:762-768. 
  26. Fioranelli M, Bottaccioli AG, Bottaccioli F, et al. Stress and Inflammation in Coronary Artery Disease: A Review Psychoneuroendocrineimmunology-Based. Front Immunol. 2018;9:2031.
  27. Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study. The Lancet. 2020;395:1054-1062.
  28. Wang D, Hu B, Hu C, et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA. 2020;323:1061-1069.
  29. Libby P, Simon DI. Inflammation and thrombosis: The clot thickens. Circulation. 2001;103:1718-1720.
  30. Caforio AL, Pankuweit S, Arbustini E, et al. Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Eur Heart J. 2013;34:2636-2648.
  31. Ma K-L, Liu Z-H, Cao C-F, et al. COVID-19 Myocarditis and Severity Factors: An Adult Cohort Study. medRxiv. 2020.
  32. Chen C, Zhou Y, Wang DW. SARS-CoV-2: A potential novel etiology of fulminant myocarditis. Herz. 2020;45:230-232. 
  33. Kociol RD, Cooper LT, Fang JC, et al. Recognition and Initial Management of Fulminant Myocarditis: A Scientific Statement From the American Heart Association. Circulation. 2020;141:69-92. 
  34. Luetkens JA, Isaak A, Zimmer S, et al. Diffuse Myocardial Inflammation in COVID-19 Associated Myocarditis Detected by Multiparametric Cardiac Magnetic Resonance Imaging. Circ Cardiovasc Imaging. 2020;13:e010897.
  35. Ferreira VM, Schulz-Menger J, Holmvang G, et al. Cardiovascular Magnetic Resonance in Nonischemic Myocardial Inflammation: Expert Recommendations. J Am Coll Cardiol. 2018;72: 3158-3176.
  36. Aretz HT, Billingham ME, Edwards WD, et al. Myocarditis. A histopathologic definition and classification. Am J Cardiovasc Pathol. 1987;1:1:3-14. 
  37. Chow LH, Radio SJ, Sears TD, McManus BM. Insensitivity of right ventricular endomyocardial biopsy in the diagnosis of myocarditis. Journal of the American College of Cardiology. 1989;14:915-920. 
  38. Beigel JH, Tomashek KM, Dodd LE, et al. Remdesivir for the Treatment of COVID-19 — Final Report. N Engl J Med. 2020;383: 1813-1826.
  39. Huang X, Sun Y, Su G, Li Y, Shuai X. Intravenous Immunoglobulin Therapy for Acute Myocarditis in Children and Adults. Int Heart J. 2019;60:359-365. 
  40. Shen C, Wang Z, Zhao F, et al. Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma. JAMA. 2020;323: 1582-1589.
  41. Evans PC, Rainger GE, Mason JC, et al. Endothelial dysfunction in COVID-19: A position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic Cardiovascular Science. Cardiovasc Res. 2020;116:2177-2184.
  42. Chavez S, Long B, Koyfman A, Liang SY. Coronavirus Disease (COVID-19): A primer for emergency physicians. Am J Emerg Med. 2020;44:220-229. 
  43. Elfiky AA. Anti-HCV, nucleotide inhibitors, repurposing against COVID-19. Life Sci. 2020;248:117477.
  44. Page RL 2nd, O’Bryant CL, Cheng D, et al. Drugs That May Cause or Exacerbate Heart Failure: A Scientific Statement From the American Heart Association. Circulation. 2016;134:e32-69. 
  45. Tonnesmann E, Kandolf R, Lewalter T. Chloroquine cardiomyopathy — a review of the literature. Immunopharmacol Immunotoxicol. 2013;35:434-442. 
  46. Liu Y, Yang Y, Zhang C, et al. Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury. Sci China Life Sci. 2020;63:364-374. 
  47. Peretto G, Sala S, Rizzo S, et al. Ventricular Arrhythmias in Myocarditis: Characterization and Relationships With Myocardial Inflammation. J Am Coll Cardiol. 2020;75:1046-1057.

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