The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Golovkin A.S.

NII kompleksnykh problem serdechno-sosudistykh zabolevaniĭ SO RAMN, Kemerovo

Grigor'ev E.V.

kafedra anesteziologii i reanimatologii Kemerovskoĭ gosudarstvennoĭ meditsinskoĭ akademii

Matveeva V.G.

NII kompleksnykh problem serdechno-sosudistykh zabolevaniĭ SO RAMN, Kemerovo

Velikanova E.A.

Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia

Role of cathepsins in pathogenesis and progressing of atherosclerosis

Authors:

Golovkin A.S., Grigor'ev E.V., Matveeva V.G., Velikanova E.A.

More about the authors

Read: 3897 times


To cite this article:

Golovkin AS, Grigor'ev EV, Matveeva VG, Velikanova EA. Role of cathepsins in pathogenesis and progressing of atherosclerosis. Russian Journal of Cardiology and Cardiovascular Surgery. 2012;5(4):9‑12. (In Russ.)

References:

  1. Gashenko E.A., Lebedeva V.A., Kovalenko V.F. i dr. Kontsentratsiya prokatepsina V i ingibitora tsisteinovykh proteaz tsistatina S v biologicheskikh zhidkostyakh pri razvitii opukholei. Byul SO RAMN 2010; 4: 110-115
  2. Gerasimov A.M., Borzova N.Yu., Kerimkulova N.V. i dr. Katepsin D - ego fiziologicheskaya rol' i ispol'zovanie v meditsine. Klin lab diagn 2009; 3: 3-5.
  3. Chen J., Tung C.H., Mahmood U. et al. In vivo imaging of proteolytic activity in atherosclerosis. Circulation 2002; 105: 2766-2771.
  4. Cheng X.W., Kuzuya M., Sasaki T. et al. Increased expression of elastolytic cysteine proteases, cathepsins S and K, in the neointima of balloon-injured rat carotid arteries. Am J Pathol 2004; 164: 243-251.
  5. Chwieralski C.E., Welte T., Bühling F. Cathepsin-regulated apoptosis. Apoptosis 2006; 11: 2: 143-149.
  6. Dansky H.M., Barlow C.B., Lominska C. et al. Adhesion of monocytes to arterial endothelium and initiation of atherosclerosis are critically dependent on vascular cell adhesion molecule-1 gene dosage. Arterioscler Thromb Vasc Biol 2001; 21: 1662-1667.
  7. Day S.M., Reeve J.L., Mundada L. et al. Cathepsin S-deficient mice display a prothrombotic phenotype. Circulation 2002; 106: 195.
  8. Fabunmi R.P., Baker A.H., Murray E.J. et al. Divergent regulation by growth factors and cytokines of 95 kDa and 72 kDa gelatinases and tissue inhibitors or metalloproteinases-1, -2, and -3 in rabbit aortic smooth muscle cells. Biochem J 1996; 315: 335-342.
  9. Fabunmi R.P., Sukhova G.K., Sugiyama S. et al. Expression of tissue inhibitor of metalloproteinases-3 in human atheroma and regulation in lesion-associated cells: a potential protective mechanism in plaque stability. Circ Res 1998; 83: 270-278.
  10. Gacko M., Ostapowicz R., Chrostek L. et al. Activity of enzymes with different subcellular localization in the blood plasma of patients with aortic aneurysm. Med Sci Monit 2005; 11: 211-213.
  11. Guicciardi M.E., Deussing J., Miyoshi H. et al. Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome. J Clin Invest 2000; 106: 1127-1137.
  12. Herrmann J., Lerman L.O., Mukhopadhyay D. et al. Angiogenesis in atherogenesis. Arterioscler Thromb Vasc Biol 2006; 26: 1948-1945.
  13. Hummel V., Kallmann B.A., Wagner S. et al. Production of MMPs in human cerebral endothelial cells and their role in shedding adhesion molecules. J Neuropathol Exp Neurol 2001; 60: 320-327.
  14. Inoue S., Egashira K., Ni W. et al. Anti-monocyte chemoattractant protein-1 gene therapy limits progression and destabilization of established atherosclerosis in apolipoprotein E-knockout mice. Circulation 2002; 106: 2700-2706.
  15. Ishisaka R., Utsumi T., Kanno T. et al. Participation of a cathepsin L-type protease in the activation of caspase-3. Cell Struct Funct 1999; 24: 465-470.
  16. Ix J.H., Shlipak M.G., Chertow G.M. et al. Association of cystatin C with mortality, cardiovascular events, and incident heart failure among persons with coronary heart disease: data from the Heart and Soul Study. Circulation 2007; 115: 173-179.
  17. Johnson J.L., George S.J., Newby A.C. et al. Divergent effects of matrix metalloproteinases 3, 7, 9, and 12 on atherosclerotic plaque stability in mouse brachiocephalic arteries. Proc Natl Acad Sci USA 2005; 102: 15 575-15 580.
  18. Jormsjo S., Wuttge D.M., Sirsjo A. et al. Differential expression of cysteine and aspartic proteases during progression of atherosclerosis in apolipoprotein E-deficient mice. Am J Pathol 2002; 161: 939-945.
  19. Khurana R., Simons M., Martin J. F. et al. Role of angiogenesis in cardiovascular disease: a critical appraisal. Circulation 2005; 112: 1813-1824.
  20. Kidd V.J., Lahti J.M., Teitz T. Proteolytic regulation of apoptosis. Semin Cell Dev Biol 2000; 11: 3: 191-201.
  21. Kowalski J., Okopien B., Madej A. et al. Levels of sICAM-1, sVCAM-1 and MCP-1 in patients with hyperlipoproteinemia IIa and -IIb. Int J Clin Pharmacol Ther 2001; 39: 48-52.
  22. Leca G., Mansur S.E., Bensussan A. Expression of VCAM-1 (CD106) by a subset of TCR γδ-bearing lymphocyte clones: involvement of a metalloprotease in the specific hydrolytic release of the soluble isoform. J Immunol 1995; 154: 1069-1077.
  23. Li W., Dalen H., Eaton J.W. et al. Apoptotic death of inflammatory cells in human atheroma. Arterioscler Thromb Vasc Biol 2001; 21: 1124-1130.
  24. Li Z., Yasuda Y., Li W. et al. Regulation of collagenase activities of human cathepsins by glycosaminoglycans. J Biol Chem 2004; 279: 5470-5479.
  25. Libby P. Changing concepts of atherogenesis. J Intern Med 2000; 247: 349-358.
  26. Lindstedt L., Lee M., Oorni K. et al. Cathepsins F and S block HDL3-induced cholesterol efflux from macrophage foam cells. Biochem Biophys Res Commun 2003; 312: 1019-1024.
  27. Liu J., Ma L., Yang J. et al. Increased serum cathepsin S in patients with atherosclerosis and diabetes. Atherosclerosis 2006; 186: 411-419.
  28. Liu J., Sukhova G.K., Yang J.T. et al. Cathepsin L expression and regulation in human abdominal aortic aneurysm, atherosclerosis, and vascular cells. Atherosclerosis 2006; 184: 302-311.
  29. Lutgens E., Gijbels M., Smook M. et al. Transforming growth factor-beta mediates balance between inflammation and fibrosis during plaque progression. Arterioscler Thromb Vasc Biol 2002; 22: 975-982.
  30. Lutgens S.P.M., Cleutjens K.B.J.M., Daemen M.J.A.P. et al. Cathepsin cysteine proteases in cardiovascular disease. FASEB J 2007; 21: 3029-3041.
  31. Lutgens S., Kisters N., Lutgens E. et al. Gene profiling of cathepsin K deficiency in atherogenesis: profibrotic but lipogenic. J Pathol 2006; 210: 334-343.
  32. Moreno P.R., Purushothaman K.R., Sirol M. et al. Neovascularization in human atherosclerosis. Circulation 2006; 113: 2245-2252.
  33. Platt M.O., Ankeny R.F., Shi G.P. et al. Expression of cathepsin K is regulated by shear stress in cultured endothelial cells and is increased in endothelium in human atherosclerosis. Am J Physiol 2006; 292: H1479-H1486.
  34. Premzl A., Turk V., Kos J. Intracellular proteolytic activity of cathepsin B is associated with capillary-like tube formation by endothelial cells in vitro. J Cell Biochem 2006; 97: 1230-1240.
  35. Purushothaman K.R., Sanz J., Zias E. et al. Atherosclerosis neovascularization and imaging. Curr Mol Med 2006; 6: 549-556.
  36. Reddy V.Y., Zhang Q.Y., Weiss S.J. Pericellular mobilization of the tissue-destructive cysteine proteinases, cathepsins B, L, and S, by human monocyte-derived macrophages. Proc Natl Acad Sci USA 1995; 92: 3849-3853.
  37. Riese R.J., Shi G.P., Villadangos J. et al. Regulation of CD1 function and NK1.1(+) T cell selection and maturation by cathepsin S. Immunity 2001; 15: 909-919.
  38. Shah P.K., Falk E., Badimon J.J. et al. Human monocytederived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques: potential role of matrix-degrading metalloproteinases and implications for plaque rupture. Circulation 1995; 92: 1565-1569.
  39. Shi G.P., Sukhova G.K., Grubb A. et al. Cystatin C deficiency in human atherosclerosis and aortic aneurysms. J Clin Invest 1999; 104: 1191-1197.
  40. Sukhova G.K., Shi G.P., Simon D.I. et al. Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells. J Clin Invest 1998; 102: 576-583.
  41. Sukhova G.K., Zhang Y., Pan J.H. et al. Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice. J Clin Invest 2003; 111: 897-906.
  42. Taleb S., Lacasa D., Bastard J. P. et al. Cathepsin S, a novel biomarker of adiposity: relevance to atherogenesis. FASEB J 2005; 19: 1540-1542.
  43. Tsukuba T., Okamoto K., Yasuda Y. et al. New functional aspects of cathepsin D and cathepsin E. Mol Cells 2000; 10: 6: 601-611.
  44. Wang G., Woo C.W., Sung F.L. et al. Increased monocyte adhesion to aortic endothelium in rats with hyperhomocysteinemia: role of chemokine and adhesion molecules. Arterioscler Thromb Vasc Biol 2002; 22: 1777-1783.
  45. Wang B., Sun J., Kitamoto S. et al. Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors. J Biol Chem 2006; 281: 6020-6029.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.