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Belevskaya A.A.

Institute of the Clinical Cardiology named after A.L. Myasnikov of National Medical Research Center for Cardiology, Moscow, Russia

Saidova M.A.

National medical research center of cardiology MH RF

Martynyuk T.V.

The Institute of Clinical Cardiology named after A.L. Myasnikov, Federal State Institution «National Medical Research Center of Сardiology», Moscow, Russia

Chazova I.E.

Federal State budget organization National Medical Research Center of Cardiology of the Ministry of healthcare of the Russian Federation, The Institute of Clinical Cardiology, Moscow, Russia

Heart remodeling and ventricular-arterial coupling in patients with IPAH and CTEPH

Authors:

Belevskaya A.A., Saidova M.A., Martynyuk T.V., Chazova I.E.

More about the authors

Journal: Russian Cardiology Bulletin. 2018;13(4): 30‑34

DOI: 10.17116/Cardiobulletin20181304130

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Table of contents

HEART REMODELING AND VENTRICULAR-ARTERIAL COUPLING IN PATIENTS WITH IPAH AND CTEPH
HEART REMODELING AND VENTRICULAR-ARTERIAL COUPLING IN PATIENTS WITH IPAH AND CTEPH

To cite this article:

Belevskaya AA, Saidova MA, Martynyuk TV, Chazova IE. Heart remodeling and ventricular-arterial coupling in patients with IPAH and CTEPH. Russian Cardiology Bulletin. 2018;13(4):30‑34. (In Russ.)
https://doi.org/10.17116/Cardiobulletin20181304130

Подписка 2026 Кардиологический вестник (Russian Cardiology Bulletin)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Ventricular-arterial coupling (VAC), defined as the interaction between ventricles and great vessels, is the key determinant of cardiac performance. To the best of our knowledge, only single Russian publications deal with assessment of VAC in patients with pulmonary hypertension. Purpose. To assess heart remodeling, ventricular interdependence and VAC in patients with IPAH and CTEPH of different severity. Material and methods. The study included 40 patients with IPAH, 40 patients with CTEPH, and 20 healthy volunteers. We use 2D and 3D echocardiography to assess heart remodeling, ventricular interdependence and VAC, right heart catheterization, 6-minute walk test. Results. Patients with IPAH and CTEPH had dilated right heart chambers, impaired right VAC, right ventricular systolic and diastolic function. Above-mentioned changes were more pronounced in patients in WHO functional class III—IV. Conclusion. Patients with IPAH and CTEPH had similar heart remodeling. Right VAC is impaired due to high pulmonary artery effective elastance.

Keywords:

idiopathic pulmonary arterial hypertension (IPAH)
chromic tromboembolic pulmonary hypertension (CTEPH)
echocardiography
heart remodeling
ventricular interaction
ventricular-arterial coupling

Authors:

Belevskaya A.A.

Institute of the Clinical Cardiology named after A.L. Myasnikov of National Medical Research Center for Cardiology, Moscow, Russia

Saidova M.A.

National medical research center of cardiology MH RF

Martynyuk T.V.

The Institute of Clinical Cardiology named after A.L. Myasnikov, Federal State Institution «National Medical Research Center of Сardiology», Moscow, Russia

Chazova I.E.

Federal State budget organization National Medical Research Center of Cardiology of the Ministry of healthcare of the Russian Federation, The Institute of Clinical Cardiology, Moscow, Russia

Close metadata

References:

  1. Chazova IE, Avdeev SN, Tsareva NA, Volkov AV, Martynyuk TV, Nakonechnikov SN. Clinical guidelines for the diagnosis and treatment of pulmonary hypertension. Terapevticheskii arkhiv. 2014;86(9):4-23. (In Russ.)
  2. Bossone E, D’Andrea A, D’Alto M, Citro R, Argiento P, Ferrara F, Cittadini A, Rubenfire M, Naeije R. Echocardiography in pulmonary arterial hypertension: from diagnosis to prognosis. J Am Soc Echocardiogr. 2013;26:1-14. https://doi.org/10.1016/j.echo.2012.10.009
  3. Santamore WP, Dell’Italia LJ. Ventricular interdependence: significant left ventricular contributions to right ventricular systolic function. Prog Cardiovasc Dis. 1998;40:289-308. https://doi.org/10.1016/s0033-0620(98)80049-2
  4. Antonini-Canterin F, Carerj S, Di Bello V Di Salvo G, La Carrubba S, Vriz O, Pavan D, Balbarini A, Nicolosi GL. Arterial stiffness and ventricular stiffness: a couple of diseases or a coupling disease? A review from the cardiologist’s point of view. Eur J Echocardiogr. 2009;10(1):36-43. https://doi.org/10.1093/ejechocard/jen236
  5. Belevskaya AA. The assessment of cardiac structure and function, interventricular interaction and ventricular-arterial coupling in patients with pulmonary hypertension of different severity: Dis... kand. med. nauk. M. 2017. (In Russ.)
  6. Yock PG, Popp RL. Noninvasive estimation of right ventricular systolic pressure by Doppler ultrasound in patients with tricuspid regurgitation. Circulation. 1984;70:657-662. https://doi.org/10.1161/01.cir.70.4.657
  7. Aduen JF, Castello R, Lozano MM, Hepler GN, Keller CA, Alvarez F, Safford RE, Crook JE, Heckman MG, Burger CD. An alternative echocardiographic method to estimate mean pulmonary artery pressure: diagnostic and clinical implications. J Am Soc Echocardiogr. 2009;22:814-819. https://doi.org/10.1016/j.echo.2009.04.007
  8. Rudski LG, Lai WW, Afilalo J, Hua L, Handschumacher MD, Chandrasekaran K, Solomon SD, Louie EK, Schiller NB. Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography. J Am SocEchocardiogr. 2010;23:685-713. https://doi.org/10.1016/j.echo.2010.05.010
  9. Nagueh SF, Middleton KJ, Kopelen HA, Zoghbi WA, Quiñones MA. Doppler tissue imaging: a noninvasive technique for evaluation of left ventricular relaxation and estimation of filling pressures. J Am Coll Cardiol. 1997;30:1527-1533. https://doi.org/10.1016/s0735-1097(97)00344-6
  10. Ryan T, Petrovic O, Dillon JC, Feigenbaum HF, Conley MJ, Armstrong W. An echocardiographic index for separation of right ventricular volume and pressure overload. J Am Coll Cardiol. 1985;5:918-924. https://doi.org/10.1016/s0735-1097(85)80433-2
  11. Sanz J, García-Alvarez A, Fernández-Friera L, Nair A, Mirelis JG, Sawit ST, Pinney S, Fuster V. Right ventriculo-arterial coupling in pulmonary hypertension: a magnetic resonance study. Heart. 2012;98(3):238-243. https://doi.org/10.1136/heartjnl-2011-300462
  12. Morimont P, Lambermont B, Ghuysen A, Gerard P, Kolh P, Lancellotti P, Tchana-Sato V, Desaive T, D’Orio V. Effective arterial elastance as an index of pulmonary vascular load. Am J Physiol Heart Circ Physiol. 2008;294(6):2736-2742. https://doi.org/10.1152/ajpheart.00796.2007
  13. Andreeva YuA, Saidova MA, Martynyuk TV, Masenko VP, Chazova IE. Tissue myocardial Doppler echocardiography in the assessment of right ventricular function among patients with pulmonary hypertension of various aetiology. Kardiovaskulyarnaya terapiya i profilaktika. 2010;9(2):27-36. (In Russ.)
  14. Grunig E, Tiede H, Enyimayew EO, Ehlken N, Seyfarth HJ, Bossone E, D’Andrea A, Naeije R, Olschewski H, Ulrich S, Nagel C, Halank M, Fischer C. Assessment and prognostic relevance of right ventricular contractile reserve in patients with severe pulmonary hypertension. Circulation. 2013;128:2005-2015. https://doi.org/10.1161/circulationaha.113.001573
  15. Ernande L, Cottin V, Leroux PY, Girerd N, Huez S, Mulliez A, Bergerot C, Ovize M, Mornex JF, Cordier JF, Naeije R, Derumeaux G. Right isovolumic contraction velocity predicts survival in pulmonary hypertension. J Am Soc Echocardiogr. 2013;26:297-306. https://doi.org/10.1016/j.echo.2012.11.011
  16. Ghio S, Klersy C, Magrini G, D’Armini AM, Scelsi L, Raineri C, Pasotti M, Serio A, Campana C, Viganò M. Prognostic relevance of the echocardiographic assessment of right ventricular function in patients with idiopathic pulmonary arterial hypertension. Int J Cardiol. 2010;140:272-278. https://doi.org/10.1016/j.ijcard.2008.11.051
  17. Ostenfeld E, Stephensen SS, Steding-Ehrenborg K, Heiberg E, Arheden H, Radegran G, Holm J, Carlsson M. Regional contribution to ventricular stroke volume is affected on the left side, but not on the right in patients with pulmonary hypertension. Int J Cardiovasc Imaging. 2016;32(8):1243-1253. https://doi.org/10.1007/s10554-016-0898-9
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