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Yakovlev M.M.

Department of Radiation Medicine, Hematology, Oncology and Toxicology, Burn Unit, A.M. Nikiforov All-Russian Centre of Emergency and Radiation Medicine, Russian Ministry of Emergency Situations, St. Petersburg, Russia

Panov A.V.

Department of Radiation Medicine, Hematology, Oncology and Toxicology, Burn Unit, A.M. Nikiforov All-Russian Centre of Emergency and Radiation Medicine, Russian Ministry of Emergency Situations, St. Petersburg, Russia

Kalmykova N.V.

Department of Radiation Medicine, Hematology, Oncology and Toxicology, Burn Unit, A.M. Nikiforov All-Russian Centre of Emergency and Radiation Medicine, Russian Ministry of Emergency Situations, St. Petersburg, Russia

Moiseev S.I.

Department of Radiation Medicine, Hematology, Oncology and Toxicology, Burn Unit, A.M. Nikiforov All-Russian Centre of Emergency and Radiation Medicine, Russian Ministry of Emergency Situations, St. Petersburg, Russia

The Use of Cellular Products for the Combined Treatment of a Giant Crural Trophic Ulcer

Authors:

Yakovlev M.M., Panov A.V., Kalmykova N.V., Moiseev S.I.

More about the authors

Journal: Journal of Venous Disorders. 2016;10(3): 151‑154

DOI: 10.17116/flebo2016103151-154

Read: 918 times

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Table of contents

THE USE OF CELLULAR PRODUCTS FOR THE COMBINED TREATMENT OF A GIANT CRURAL TROPHIC ULCER
THE USE OF CELLULAR PRODUCTS FOR THE COMBINED TREATMENT OF A GIANT CRURAL TROPHIC ULCER

To cite this article:

Yakovlev MM, Panov AV, Kalmykova NV, Moiseev SI. The Use of Cellular Products for the Combined Treatment of a Giant Crural Trophic Ulcer. Journal of Venous Disorders. 2016;10(3):151‑154. (In Russ.)
https://doi.org/10.17116/flebo2016103151-154

Подписка 2026 Флебология (Journal of Venous Disorders)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The use of skin cells-based products is one of the components of the comprehensive approach to the management of trophic ulcers. Dermal fibroblasts in the form of suspension or dermal equivalent are simple and effective agents for stimulation of the granulation tissue formation, wound epithelization and autologous skin grafting. The present article describes a case of complete closure of a crural trophic ulcer with use of cellular products based on the patient’s autologous materials, such as dermal fibroblasts and blood plasma.

Keywords:

trophic ulcers
fibroblasts
dermal equivalent

Authors:

Yakovlev M.M.

Department of Radiation Medicine, Hematology, Oncology and Toxicology, Burn Unit, A.M. Nikiforov All-Russian Centre of Emergency and Radiation Medicine, Russian Ministry of Emergency Situations, St. Petersburg, Russia

Panov A.V.

Department of Radiation Medicine, Hematology, Oncology and Toxicology, Burn Unit, A.M. Nikiforov All-Russian Centre of Emergency and Radiation Medicine, Russian Ministry of Emergency Situations, St. Petersburg, Russia

Kalmykova N.V.

Department of Radiation Medicine, Hematology, Oncology and Toxicology, Burn Unit, A.M. Nikiforov All-Russian Centre of Emergency and Radiation Medicine, Russian Ministry of Emergency Situations, St. Petersburg, Russia

Moiseev S.I.

Department of Radiation Medicine, Hematology, Oncology and Toxicology, Burn Unit, A.M. Nikiforov All-Russian Centre of Emergency and Radiation Medicine, Russian Ministry of Emergency Situations, St. Petersburg, Russia

Close metadata

References:

  1. Goryunov SV. Trophic ulcers. In: Savel’ev V.S., Kirienko A.I., eds. Clinical surgery: national guidelines. M.: GEOTAR-Media; 2008;(1): 627-632. (In Russ).
  2. Nathoo R, Howe N, Cohen G. Skin substitutes: an overview of the key players in wound management. J Clin Aesthet Dermatol. 2014;7(10):44-48.
  3. Han SK, Kim HS, Kim WK. Efficacy and safety of fresh fibroblast allografts in the treatment of diabetic foot ulcers. Dermatol Surg. 2009;35(9):1342-1348. doi: 10.1111/j.1524-4725.2009.01239.x
  4. Kirsner RS, Marston WA, Snyder RJ, Lee TD, Cargill DI, Slade HB. Spray-applied cell therapy with human allogeneic fibroblasts and keratinocytes for the treatment of chronic venous leg ulcers: a phase 2, multicentre, double-blind, randomised, placebo-controlled trial. Lancet. 2012;380(9846):977-985. doi: 0.1016/S0140-6736(12)60644-8
  5. Santema TK, Poyck PP, Ubbink DT. Systematic review and meta-analysis of skin substitutes in the treatment of diabetic foot ulcers: Highlights of a Cochrane Systematic review. Wound Repair Regen. 2016;6. doi: 10.1111/wrr.12434
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