Necrotizing sarcoid granulomatosis

Semenova L.A.; Radenska-Lopovok S.G.; Burtseva S.A.; Berezovskiĭ Iu.S.; Lepekha L.N.

doi:https://doi.org/10.17116/patol201678545-49

Semenova L.A.

Nasonova Research Institute of Rheumatology, Moscow, Russia

Radenska-Lopovok S.G.

FGBU "Nauchno-issledovatel'skiĭ institut revmatologii im. V.A. Nasonovoĭ" RAMN, Moskva

ORCID: 0000-0002-4669-260X

Burtseva S.A.

Central Research Institute of Tuberculosis, Moscow, Russia

Berezovskiĭ Iu.S.

FGBU "TsNIIT" RAMN

Lepekha L.N.

Central Research Institute of Tuberculosis, Moscow, Russia

Necrotizing sarcoid granulomatosis

Authors:

Semenova L.A., Radenska-Lopovok S.G., Burtseva S.A., Berezovskiĭ Iu.S., Lepekha L.N.

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Journal: Russian Journal of Archive of Pathology. 2016;78(5): 45‑49

DOI: 10.17116/patol201678545-49

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To cite this article:

Semenova LA, Radenska-Lopovok SG, Burtseva SA, Berezovskiĭ IuS, Lepekha LN. Necrotizing sarcoid granulomatosis. Russian Journal of Archive of Pathology. 2016;78(5):45‑49. (In Russ.)
https://doi.org/10.17116/patol201678545-49

Подписка 2026 Архив патологии (Russian Journal of Archive of Pathology)

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Abstract:

Necrotizing sarcoid granulomatosis (NSG) belongs to productive small-vessel vasculitis with the formation of sarcoid-like granulomas, which is accompanied by ischemic necrosis of varying degrees and duration. The disease involves the lung only. The clinical symptoms of the disease are nonspecific so the latter is detected rather rarely. The main diagnostic technique is morphological examination. Immune complex inflammation develops in the vessel walls with the formation of macrophage-histiocytic granulomas that do not contain epithelioid cells. The etiology and pathogenesis of NSG remain little studied. Its differential diagnosis is mainly presented with tuberculosis, sarcoidosis, and granulomatosis with polyangiitis.

Keywords:

necrotizing sarcoid granulomatosis

sarcoidosis

granulomatosis with polyangiitis

tuberculosis

Authors:

Semenova L.A.

Nasonova Research Institute of Rheumatology, Moscow, Russia

Radenska-Lopovok S.G.

FGBU "Nauchno-issledovatel'skiĭ institut revmatologii im. V.A. Nasonovoĭ" RAMN, Moskva

ORCID: 0000-0002-4669-260X

Burtseva S.A.

Central Research Institute of Tuberculosis, Moscow, Russia

Berezovskiĭ Iu.S.

FGBU "TsNIIT" RAMN

Lepekha L.N.

Central Research Institute of Tuberculosis, Moscow, Russia

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References:

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