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Amelin A.V.

Pavlov First Saint Petersburg State Medical University

Antipenko E.A.

Privolzhsky Research Medical University

Barantsevich E.R.

Pavlov First Saint Petersburg State Medical University

Barulin A.E.

Volgograd State Medical University

Bykov Yu.N.

Irkutsk State Medical University

Vizilo T.L.

Kemerovo State Medical University

Davydov O.S.

Research Institute of General Pathology and Pathophysiology

Devlikamova F.I.

Kazan State Medical Academy, Branch of the Russian Medical Academy for Continuous Professional Education

Doronina O.B.

Novosibirsk State Medical University

Isaeva N.V.

Voino-Yasenetsky Krasnoyarsk State Medical University

Iskra D.A.

St. Petersburg State Pediatric Medical University

Kalinsky P.P.

Pacific State Medical University

Karakulova Yu.V.

Wagner Perm State Medical University

Karpov S.M.

Stavropol State Medical University

Karpova M.I.

South Ural State Medical University

Korsunskaya L.L.

Vernadsky Crimean Federal University

Kukushkin M.L.

Research Institute of General Pathology and Pathophysiology

Kurushina O.V.

Volgograd State Medical University

Parfenov V.A.

Sechenov First Moscow State Medical University (Sechenov Univercity)

Parkhomenko E.V.

Altai State Medical University

Fedin A.I.

Pirogov Russian National Research Medical University

Khabirov F.A.

Kazan State Medical Academy, Branch of the Russian Medical Academy for Continuous Professional Education

Churyukanov M.V.

Sechenov First Moscow State Medical University (Sechenov Univercity)

Shirokov V.A.

Ural State Medical University

Shchukin I.A.

Pirogov Russian National Research Medical University

Resolution of the Council of Experts on the Treatment of Radiculopathy “New approaches to the treatment of back pain”

Authors:

Amelin A.V., Antipenko E.A., Barantsevich E.R., Barulin A.E., Bykov Yu.N., Vizilo T.L., Davydov O.S., Devlikamova F.I., Doronina O.B., Isaeva N.V., Iskra D.A., Kalinsky P.P., Karakulova Yu.V., Karpov S.M., Karpova M.I., Korsunskaya L.L., Kukushkin M.L., Kurushina O.V., Parfenov V.A., Parkhomenko E.V., Fedin A.I., Khabirov F.A., Churyukanov M.V., Shirokov V.A., Shchukin I.A.

More about the authors

Journal: Russian Journal of Pain. 2025;23(1): 84‑90

DOI: 10.17116/pain20252301184

Read: 2311 times

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Table of contents

RESOLUTION OF THE COUNCIL OF EXPERTS ON THE TREATMENT OF RADICULOPATHY “NEW APPROACHES TO THE TREATMENT OF BACK PAIN”
RESOLUTION OF THE COUNCIL OF EXPERTS ON THE TREATMENT OF RADICULOPATHY “NEW APPROACHES TO THE TREATMENT OF BACK PAIN”

To cite this article:

Amelin AV, Antipenko EA, Barantsevich ER, et al. . Resolution of the Council of Experts on the Treatment of Radiculopathy “New approaches to the treatment of back pain”. Russian Journal of Pain. 2025;23(1):84‑90. (In Russ.)
https://doi.org/10.17116/pain20252301184

Подписка 2025 Российский журнал боли (Russian Journal of Pain)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

On November 08, 2024 in Moscow, under the auspices of the Russian Society for the Study of Pain (RSSP), a Council of Experts was held, during which leading specialists in the field of neurology, who have a high level of expertise in the treatment of back pain, discussed modern approaches to the therapy of discogenic lumbosacral radiculopathy (DLSR). The Council actualized the leading pathogenetic mechanisms of the disease onset and progression; discussed the mechanisms of pathogenesis, which are currently still insufficiently affected by pharmacotherapeutic intervention. Conservative therapy of DLSR is effective and allows to avoid surgical treatment in the majority (more than 90%) of cases. The leading role in conservative therapy of DLSR is played by informing the patient about the benign nature of DLSR, the possibility of spontaneous regression of disc herniation, methods of kinesiotherapy under the supervision of a specialist, epidural administration of local anesthetics and glucocorticoids in the acute period of the disease. In real practice, non-steroidal anti-inflammatory drugs, anticonvulsants are widely used, but their effectiveness remains controversial, so the search for new methods of conservative therapy is relevant. The experts noted the importance of the approach to the treatment of the problem under consideration from the position of its pathogenesis and discussed the introduction of new groups of drugs, emphasizing the need to expand clinical recommendations in favor of drugs with pathogenetically justified and complex mechanisms of action in back pain. The results of RCTs and the experience of clinical application of parenteral preparation of triterpene saponin escin — L-lysine escinate in different groups of patients with DLSR were discussed in detail. The expediency of conducting a multicenter placebo-controlled study of the efficacy of escin — L-lysine escinate in acute DLSR was noted.

Keywords:

lumbosacral pain
discogenic lumbosacral radiculopathy
spinal nerve root
intervertebral disc injury
phospholipase A2
impaired venous blood flow
escin
L-lysine escinate

Authors:

Amelin A.V.

Pavlov First Saint Petersburg State Medical University

Antipenko E.A.

Privolzhsky Research Medical University

Barantsevich E.R.

Pavlov First Saint Petersburg State Medical University

Barulin A.E.

Volgograd State Medical University

Bykov Yu.N.

Irkutsk State Medical University

Vizilo T.L.

Kemerovo State Medical University

Davydov O.S.

Research Institute of General Pathology and Pathophysiology

Devlikamova F.I.

Kazan State Medical Academy, Branch of the Russian Medical Academy for Continuous Professional Education

Doronina O.B.

Novosibirsk State Medical University

Isaeva N.V.

Voino-Yasenetsky Krasnoyarsk State Medical University

Iskra D.A.

St. Petersburg State Pediatric Medical University

Kalinsky P.P.

Pacific State Medical University

Karakulova Yu.V.

Wagner Perm State Medical University

Karpov S.M.

Stavropol State Medical University

Karpova M.I.

South Ural State Medical University

Korsunskaya L.L.

Vernadsky Crimean Federal University

Kukushkin M.L.

Research Institute of General Pathology and Pathophysiology

Kurushina O.V.

Volgograd State Medical University

Parfenov V.A.

Sechenov First Moscow State Medical University (Sechenov Univercity)

Parkhomenko E.V.

Altai State Medical University

Fedin A.I.

Pirogov Russian National Research Medical University

Khabirov F.A.

Kazan State Medical Academy, Branch of the Russian Medical Academy for Continuous Professional Education

Churyukanov M.V.

Sechenov First Moscow State Medical University (Sechenov Univercity)

Shirokov V.A.

Ural State Medical University

Shchukin I.A.

Pirogov Russian National Research Medical University

Received:

14.01.2025

Accepted:

22.01.2025

Close metadata

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