BACKGROUND
Cardiac valve repair with autopericardium make possible to restore normal hemodynamic parameters in patients with heart valve pathology using their own native tissues which are less biodegradable. In such this approach there are no side-reactions and requirement in long-term anticoagulants taking. A statistical analysis of the normal size of the mitral valve was carried out on autopsy material and the methods of mathematical modeling used to create stencils necessary for cutting out the leaflets and primary (marginal) chords from the autopericardium during reconstruction were described.
OBJECTIVE
Development a pilot version of a universal mathematical model for determining the size of the mitral valve leaflets and the marginal (primary) chords for mitral valve reconstruction based on autopsy material.
MATERIAL AND METHODS
Were analyzed 21 hearts after autopsy of people died at the age of 25 to 68 years from non-cardiac causes. The size and relative position of the valvular apparatus and subvalvular structures were measured. The received information was processed using the statistical package IBM SPSS Statistics 23.0. The following methods were used: the Kruskal—Wallis test, the calculation of the Pearson correlation coefficient and the construction of a linear regression. The criteria for exclusion from the study were death from cardiac causes, a history of heart disease, previous cardiac surgery and childhood.
RESULTS
A mathematical model of the mitral valve structure of the heart, based on the known diameter of the fibrous annulus of the valve, is presented, and formulas are obtained for calculating the size of the leaflets, as well as the primary chords. After calculating the size of the leaflets, they must be drawn on the surface of the pericardial sheet prepared in advance, adding 2 millimeters to the borders of the leaflet (correction for suturing). The calculations need experimental confirmation.
CONCLUSION
The study of the topographic and anatomical relationships of the mitral valve structure has great practical importance in reconstructive operations both on the valvular apparatus of the heart in case of damage to the leaflets and subvalvular structures, and when it is necessary to perform a complete valve replacement.
