Severe postoperative intracranial hemorrhagic complications in a neurosurgical patient with von Willebrand disease not diagnosed before surgery (a case report and literature review)

Lubnin A.Yu.; Konovalov A.N.; Lasunin N.V.; Abramov T.A.; Bulanov A.Yu.; Galstyan G.M.; Polevodova O.A.; Moshkin A.V.; Gadjieva O.A.; Manushkova A.A.

doi:https://doi.org/10.17116/neiro201882356

Lubnin A.Yu.

Moscow Regional Research Institute of Obstetrics and Gynecology, Ministry of Health of the Moscow Region, Moscow, Russia, N.N. Burdenko Research Institute of Neurosurgery, Moscow, Russia, Department of Obstetrics and Gynecology, M.F. Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia

RSCI AuthorID: 370609
Scopus AuthorID: 57192157123
ORCID: 0000-0003-2595-5877

Konovalov A.N.

Burdenko Neurosurgical Institute, Moscow, Russian Federation

Lasunin N.V.

FGBU "NII neĭrokhirurgii im. N.N. Burdenko" RAMN, Moskva

Abramov T.A.

Burdenko National Research Center for Neurosurgery of the Ministry of Health of the Russian Federation, Moscow, Russia

Bulanov A.Yu.

St. Petersburg, Russia

Galstyan G.M.

National Research Center for Hematology, Moscow, Russia

Polevodova O.A.

National Research Center for Hematology, Moscow, Russia

Moshkin A.V.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

ORCID: 0000-0002-9965-4578

Gadjieva O.A.

Federal State Autonomous Institution «N.N. Burdenko National Medical Research Center for Neurosurgery» of the Ministry of Healthcare of the Russian Federation, Moscow, Russia, 125047, Moscow, 4-th Tverskaya-Yamskaya str.,16, Russia

Manushkova A.A.

Burdenko Neurosurgical Institute, 4-ya Tverskaya-Yamskaya Str., 16, Moscow, Russia, 125047

Severe postoperative intracranial hemorrhagic complications in a neurosurgical patient with von Willebrand disease not diagnosed before surgery (a case report and literature review)

Authors:

Lubnin A.Yu., Konovalov A.N., Lasunin N.V., Abramov T.A., Bulanov A.Yu., Galstyan G.M., Polevodova O.A., Moshkin A.V., Gadjieva O.A., Manushkova A.A.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2018;82(3): 56‑65

DOI: 10.17116/neiro201882356

Read: 6679 times

To cite this article:

Lubnin AYu, Konovalov AN, Lasunin NV, et al. . Severe postoperative intracranial hemorrhagic complications in a neurosurgical patient with von Willebrand disease not diagnosed before surgery (a case report and literature review). Burdenko's Journal of Neurosurgery. 2018;82(3):56‑65. (In Russ., In Engl.)
https://doi.org/10.17116/neiro201882356

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)

Использование инфографики авторами научных работ

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Abstract:

The article describes a rare clinical case of a patient with previously undiagnosed von Willebrand disease and basal meningioma; an intracranial neurosurgical intervention was complicated by delayed intracranial hematomas, both at the resected tumor site and distantly. The diagnosis of von Willebrand disease was established only after special hematology tests and only after surgery. Despite the use of specific therapy, the patient died due to intracranial hemorrhagic complications in the postoperative period. The paper discusses the problem of preoperative diagnosis of asymptomatic hemostasis disorders in neurosurgical patients and potential ways of its solution.

Keywords:

hemostasis disorders

von Willebrand disease

neurosurgery

postoperative hematomas

Authors:

Lubnin A.Yu.

RSCI AuthorID: 370609
Scopus AuthorID: 57192157123
ORCID: 0000-0003-2595-5877

Konovalov A.N.

Burdenko Neurosurgical Institute, Moscow, Russian Federation

Lasunin N.V.

FGBU "NII neĭrokhirurgii im. N.N. Burdenko" RAMN, Moskva

Abramov T.A.

Burdenko National Research Center for Neurosurgery of the Ministry of Health of the Russian Federation, Moscow, Russia

Bulanov A.Yu.

St. Petersburg, Russia

Galstyan G.M.

National Research Center for Hematology, Moscow, Russia

Polevodova O.A.

National Research Center for Hematology, Moscow, Russia

Moshkin A.V.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

ORCID: 0000-0002-9965-4578

Gadjieva O.A.

Manushkova A.A.

Burdenko Neurosurgical Institute, 4-ya Tverskaya-Yamskaya Str., 16, Moscow, Russia, 125047

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References:

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