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Smulevich A.B.

Sechenov First Moscow State Medical University (Sechenov University);
Mental Health Research Center

Lvov A.N.

Central State Medical Academy of the Department of Presidential Affairs of the Russian Federation;
Medical Scientific and Educational Institute of the Lomonosov Moscow State University

Fomina D.S.

Sechenov First Moscow State Medical University (Sechenov University);
City Clinical Hospital No. 52

Romanov D.V.

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Lobanova V.M.

Mental Health Research Center

Skandaryan A.A.

Sechenov First Moscow State Medical University (Sechenov University)

Samotsvetova M.D.

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Sedova E.L.

City Clinical Hospital No. 52

Psychosomatic sets of symptoms in schizotypal personality disorder

Authors:

Smulevich A.B., Lvov A.N., Fomina D.S., Romanov D.V., Lobanova V.M., Skandaryan A.A., Samotsvetova M.D., Sedova E.L.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(7): 46‑54

DOI: 10.17116/jnevro202512507146

Read: 1914 times

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Table of contents

PSYCHOSOMATIC SETS OF SYMPTOMS IN SCHIZOTYPAL PERSONALITY DISORDER
PSYCHOSOMATIC SETS OF SYMPTOMS IN SCHIZOTYPAL PERSONALITY DISORDER

To cite this article:

Smulevich AB, Lvov AN, Fomina DS, et al. Psychosomatic sets of symptoms in schizotypal personality disorder. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(7):46‑54. (In Russ.)
https://doi.org/10.17116/jnevro202512507146

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
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Recommended articles:
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Abstract:

OBJECTIVE

To establish the functional activity of pseudoallergy sets of symptom complexes manifesting as a part of the schizotypal personality disorder.

MATERIAL AND METHODS

The study sample included 23 cases with manifestations resembling the clinical presentation of allergic dermatoses and skin symptoms of allergic diseases with no signs of somatic-related allergic sets of symptoms (medical history/laboratory studies). The patients were examined using clinical, laboratory, and psychometric methods followed by statistical data processing.

RESULTS

There are two types of functional activity of pseudoallergic reactions: “amplification” and “overlap” of clinical manifestations of schizotypal personality disorder. In accordance with the hypothesis based on the data obtained, pseudoallergy refers to adaptive dimensions (a marker of endogenous process stabilization), ensuring the stability of manifestations of schizotypal personality disorder as a part of latent schizophrenia. To confirm the hypothesis, modern neurobiological and genetic research data were used.

CONCLUSION

From the point of view of clinical practice, pseudoallergy is a severe psychosomatic disorder that requires multidisciplinary specialized care with the involvement of allergologists-immunologists and psychiatrists focused on psychosomatic medicine.

Keywords:

schizotypal personality disorder
schizotypal disorder
schizophrenic spectrum disorders
pseudoallergy
psychosomatic disorders

Authors:

Smulevich A.B.

Sechenov First Moscow State Medical University (Sechenov University);
Mental Health Research Center

Lvov A.N.

Central State Medical Academy of the Department of Presidential Affairs of the Russian Federation;
Medical Scientific and Educational Institute of the Lomonosov Moscow State University

Fomina D.S.

Sechenov First Moscow State Medical University (Sechenov University);
City Clinical Hospital No. 52

Romanov D.V.

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Lobanova V.M.

Mental Health Research Center

Skandaryan A.A.

Sechenov First Moscow State Medical University (Sechenov University)

Samotsvetova M.D.

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Sedova E.L.

City Clinical Hospital No. 52

Received:

11.04.2025

Accepted:

11.05.2025

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