A possible relationship between disturbed interhemispheric asymmetry and a decrease in perineuronal oligodendrocytes in schizophrenia

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Vostrikov V.M.

FGBU "Nauchnyĭ tsentr psikhicheskogo zdorov'ia" RAMN, Moskva

Uranova N.A.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva

A possible relationship between disturbed interhemispheric asymmetry and a decrease in perineuronal oligodendrocytes in schizophrenia

Authors:

Vostrikov V.M., Uranova N.A.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2016;116(8): 70‑73

DOI: 10.17116/jnevro20161168170-73

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To cite this article:

Vostrikov VM, Uranova NA. A possible relationship between disturbed interhemispheric asymmetry and a decrease in perineuronal oligodendrocytes in schizophrenia. S.S. Korsakov Journal of Neurology and Psychiatry. 2016;116(8):70‑73. (In Russ.)
https://doi.org/10.17116/jnevro20161168170-73

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)

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Abstract:

Objective. To specify a possible role of oligodendrocyte deficit in the development of interhemispheric asymmetry. Material and methods. Perineuronal oligodendrocytes were counted in layer III, Broadmann area 39, in Nissl-stained sections in both hemispheres of post-mortem brain samples of patients with schizophrenia and controls (healthy people). Results and conclusion. The left-hemispheric asymmetry of perineuronal oligodendrocytes was found in the control group. A decrease of this parameter by 22% and the absence of the interhemispheric asymmetry were noted in patients with schizophrenia. It has been concluded that perineuronal oligodendrocyte deficit in the inferior parietal cortex in schizophrenia can contribute significantly to disturbed interhemispheric asymmetry of this brain structure.

Keywords:

perineuronal oligodendrocytes

morphometry

schizophrenia

interhemispheric asymmetry

Authors:

Vostrikov V.M.

FGBU "Nauchnyĭ tsentr psikhicheskogo zdorov'ia" RAMN, Moskva

Uranova N.A.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva

Close metadata

References:

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