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Belousova E.D.

Moskovskiĭ NII pediatrii i detskoĭ khirurgii

Rational polytherapy of epilepsy in children

Authors:

Belousova E.D.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2014;114(4‑2): 35‑40

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RATIONAL POLYTHERAPY OF EPILEPSY IN CHILDREN
RATIONAL POLYTHERAPY OF EPILEPSY IN CHILDREN

To cite this article:

Belousova ED. Rational polytherapy of epilepsy in children. S.S. Korsakov Journal of Neurology and Psychiatry. 2014;114(4‑2):35‑40. (In Russ.)

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
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Abstract:

About 30% of patients with epilepsy are resistant to pharmacological treatment. These patients benefit from combinational therapy with two or more antiepileptic drugs (AEDs). The management of resistant epileptic patients with AEDs combinations is based on the pharmacokinetic and pharmacodynamic interactions between AEDs. The article reviews the data on interactions between widely used AEDs.

Keywords:

epilepsy
children
polytherapy
AEDs
pharmacodynamic interactions
pharmacokinetic interactions

Authors:

Belousova E.D.

Moskovskiĭ NII pediatrii i detskoĭ khirurgii

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