Indicators of intracranial pressure (ICP) and cerebral compliance in 48 patients with primary non-traumatic intracerebral hemorrhages who underwent surgery using precise aspiration and local fibrinolysis were studied. Based on clinical and neuroimaging data, ICP indicators and cerebral compliance, we can evaluate the compressive influence of the cerebral hematoma, perform the dynamic control of fibrinolysis efficacy and intracerebral hematoma aspiration as well as of dislocation syndrome's regress and predict outcomes of disease. The restoration of ICP indicators, cerebral compliance and elimination of middle structure dislocation can be used as criteria of surgery effectiveness. At the same time, the residual volume of the hemorrhage (within 20 ml) during the elimination of compression does not exert any significant effect on the course and outcome.