Aim of this study is to substantiate the effectiveness of continuous-cycle technology of rehabilitation of patients with chronic obstructive pulmonary disease (COPD) on an outpatient basis. Material and methods. 140 patients with moderate to severe (stage II—III) COPD were examined: 82% with chronic bronchitis phenotype and 18% — with emphysema phenotype. 44% of patients had frequent exacerbations. Patients were admitted to outpatient rehabilitation after stages I and II because of the exacerbation of the disease. 2 comparable groups were formed: the primary group included 68 patients who were engaged in active physical rehabilitation according to a continuous-cycle technique for 10—12 months; the comparison group consisted of 72 patients receiving only basic drug therapy. Continuous-cycle technique included: regular exercise therapy, cycling and procedures that improve tolerance to them (hardware chest vibration, chlorpromazine electrophoresis), oxygen cocktail, general ultraviolet radiation in the unfavorable period of the year. Diagnostics of early signs of an exacerbation of the disease and prophylactic prescription of physiotherapeutic procedures were carried out. Results and discussion. During the year of observation during treatment, only 4 cases failed to prevent full exacerbation of the disease. During the year, in the patients of the primary group, in contrast to the comparison group, there was a significant improvement in the clinical signs of the disease, an increase in VC, an improvement in bronchial patency, an increase in physical performance and exercise tolerance, and a decrease in the activity of systemic inflammation. A year later, we registered an improvement in the course of the disease n 70% of patients of the primary group, and only stabilization of the process — in 82% of the comparison group. Frequency of exacerbations in the primary group decreased 5.1 times, which was 3.9 times more significant than in the comparison group.