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Radtsig E.Yu.

Pirogov Russian National Research Medical University;
Morozov Children’s City Clinical Hospital

Zelikovich E.I.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology;
Russian Medical Academy for Continuous Professional Education;
Sverzhevsky Research Clinical Institute of Otorhinolaryngology

Egina A.D.

Pirogov Russian National Research Medical University

Bakanova O.V.

Pirogov Russian National Research Medical University

Aldakimova D.A.

Pirogov Russian National Research Medical University

Polunin M.M.

Pirogov Russian National Research Medical University;
Morozov Children’s City Clinical Hospital

Olfactory bulbs aplasia as a reason of isolated congenital anosmia in a 9-year-old child (clinical case)

Authors:

Radtsig E.Yu., Zelikovich E.I., Egina A.D., Bakanova O.V., Aldakimova D.A., Polunin M.M.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2025;90(6): 129‑132

DOI: 10.17116/otorino202590061129

Read: 417 times

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Table of contents

OLFACTORY BULBS APLASIA AS A REASON OF ISOLATED CONGENITAL ANOSMIA IN A 9-YEAR-OLD CHILD (CLINICAL CASE)
OLFACTORY BULBS APLASIA AS A REASON OF ISOLATED CONGENITAL ANOSMIA IN A 9-YEAR-OLD CHILD (CLINICAL CASE)

To cite this article:

Radtsig EYu, Zelikovich EI, Egina AD, Bakanova OV, Aldakimova DA, Polunin MM. Olfactory bulbs aplasia as a reason of isolated congenital anosmia in a 9-year-old child (clinical case). Russian Bulletin of Otorhinolaryngology. 2025;90(6):129‑132. (In Russ.)
https://doi.org/10.17116/otorino202590061129

Подписка 2026 Вестник оториноларингологии (Russian Bulletin of Otorhinolaryngology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Complaints about olfactory disorders in children are extremely rare. This article describes a case of a 9-year-old girl who visited an otorhinolaryngologist due to the absence of smell perception. The examination results revealed congenital isolated anosmia caused by the absence of olfactory bulbs. The causes of congenital anosmia (both syndromic and isolated) are discuss.

Keywords:

congenital isolated anosmia
syndromes with olfactory impairment
children
olfactory impairment
aplasia of the olfactory bulbs
absence of the olfactory groove

Authors:

Radtsig E.Yu.

Pirogov Russian National Research Medical University;
Morozov Children’s City Clinical Hospital

Zelikovich E.I.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology;
Russian Medical Academy for Continuous Professional Education;
Sverzhevsky Research Clinical Institute of Otorhinolaryngology

Egina A.D.

Pirogov Russian National Research Medical University

Bakanova O.V.

Pirogov Russian National Research Medical University

Aldakimova D.A.

Pirogov Russian National Research Medical University

Polunin M.M.

Pirogov Russian National Research Medical University;
Morozov Children’s City Clinical Hospital

Received:

12.05.2025

Accepted:

27.06.2025

Close metadata

References:

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  2. Camacho M, Castelo-Branco C. Two Sisters with Kallmann Syndrome, Gonadal Dysgenesis, and Multiple Neuromuscular and Endocrine Disorders: Report of Two Cases with Description of an Unusual Association. Reproductive Sciences. 2022;29(10): 2859-2863. https://doi.org/10.1007/s43032-022-00897-z
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  4. Di Rienzo L, Artuso A, Colosimo C. Isolated congenital agenesis of the olfactory bulbs and tracts in a child without Kallmann’s syndrome. The Annals of Otology, Rhinology, and Laryngology. 2002;111(7 Pt 1):657-660.  https://doi.org/10.1177/000348940211100715
  5. Coimbra C, Cunha A, Ferreira EC, Condé A. Isolated olfactory bulbs agenesis: An extremely rare entity. Acta Otorrinolaringologica Espanola. 2016;67(4):242-244.  https://doi.org/10.1016/j.otorri.2015.07.004
  6. Saw C, Friesen ND, Bartley A. An Extremely Rare Cause of Isolated Congenital Anosmia. Case Reports in Otolaryngology. 2022; 2022:9692716. https://doi.org/10.1016/j.otorri.2015.07.004
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  8. Karstensen HG, Tommerup N. Isolated and syndromic forms of congenital anosmia. Clinical Genetics. 2012;81(3):210-215.  https://doi.org/10.1111/j.1399-0004.2011.01776.x
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  10. Sailani MR, Jingga I, MirMazlomi SH, Bitarafan F, Bernstein JA, Snyder MP, Garshasbi M. Isolated Congenital Anosmia and CNGA2 Mutation. Scientific Reports. 2017;7(1):2667. https://doi.org/10.1038/s41598-017-02947-y
  11. Alotaibi NH, Alrashed M, Drad MK, Abu-Safieh L, Almobarak AA, Baz B, Farzan RA, Alsuhaibani MS, Al-Alsheikh Y. Isolated Congenital Anosmia: Case Report and Literature Review. Ear, Nose, and Throat Journal. 2022;2022:1455613221111496. https://doi.org/10.1177/01455613221111496/
  12. Radtsig EYu, Egina AD, Bakanova OV, Aldakimova DA. Features of olfactory function assessment in children. Pediatriya. Consilium Medicum. 2025;1:70-73. (In Russ.). https://doi.org/10.26442/26586630.2025.1.203142
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