Raman microspectroscopy in the diagnosis of skin malignancies

Timurzieva A.B.; Popadiuk V.I.; Fedina M.S.; Rimskaya E.N.; Shelygina S.N.; Kudrin K.G.

doi:https://doi.org/10.17116/otorino20259002137

Timurzieva A.B.

Semashko National Research Institute of Public Health;
Patrice Lumumba Peoples’ Friendship University of Russia;
Lebedev Physical Institute of the Russian Academy of Sciences

ORCID: 0000-0003-1817-3228

Popadiuk V.I.

Patrice Lumumba Peoples’ Friendship University of Russia

ORCID: 0000-0003-3309-4683

Fedina M.S.

Russian University of Medicine

ORCID: 0000-0003-4477-1176

Rimskaya E.N.

Lebedev Physical Institute of the Russian Academy of Sciences

ORCID: 0000-0001-7802-0720

Shelygina S.N.

Lebedev Physical Institute of the Russian Academy of Sciences

ORCID: 0000-0002-2964-5430

Kudrin K.G.

Lebedev Physical Institute of the Russian Academy of Sciences;
Sechenov First Moscow State Medical University

ORCID: 0000-0001-7041-4557

Raman microspectroscopy in the diagnosis of skin malignancies

Authors:

Timurzieva A.B., Popadiuk V.I., Fedina M.S., Rimskaya E.N., Shelygina S.N., Kudrin K.G.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2025;90(2): 37‑40

DOI: 10.17116/otorino20259002137

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To cite this article:

Timurzieva AB, Popadiuk VI, Fedina MS, Rimskaya EN, Shelygina SN, Kudrin KG. Raman microspectroscopy in the diagnosis of skin malignancies. Russian Bulletin of Otorhinolaryngology. 2025;90(2):37‑40. (In Russ.)
https://doi.org/10.17116/otorino20259002137

Подписка 2026 Вестник оториноларингологии (Russian Bulletin of Otorhinolaryngology)

Использование инфографики авторами научных работ

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INTRODUCTION

The development of methods for early diagnosis of tumor diseases of the head and neck is one of the most important areas of biomedicine and healthcare in general. Special attention should be paid to consideration of issues related to the diagnosis of malignant neoplasms of the skin of the head and neck area. In this aspect, confocal Raman microspectroscopy is of interest.

OBJECTIVE

To demonstrate the feasibility of using Raman microspectroscopy to differentiate intact skin from malignant skin neoplasms.

MATERIAL AND METHODS

The study used Raman microspectroscopy with an excitation wavelength of 532 nm to diagnose basal cell carcinoma and squamous cell carcinoma of the skin and differentiate them from intact skin.

RESULTS

During the study, spectra of intact skin and skin neoplasms in the head and neck region (basal cell and squamous cell carcinoma of the skin) were obtained.

CONCLUSION

The results of the study can be used in the future for optical biopsy and early diagnosis of tumors.

Keywords:

head and neck tumors

Raman microspectroscopy

early diagnosis of cancer

optical biopsy

basal cell carcinoma of the skin

squamous cell carcinoma of the skin

intact skin tissue

Authors:

Timurzieva A.B.

Semashko National Research Institute of Public Health;
Patrice Lumumba Peoples’ Friendship University of Russia;
Lebedev Physical Institute of the Russian Academy of Sciences

ORCID: 0000-0003-1817-3228

Popadiuk V.I.

Patrice Lumumba Peoples’ Friendship University of Russia

ORCID: 0000-0003-3309-4683

Fedina M.S.

Russian University of Medicine

ORCID: 0000-0003-4477-1176

Rimskaya E.N.

Lebedev Physical Institute of the Russian Academy of Sciences

ORCID: 0000-0001-7802-0720

Shelygina S.N.

Lebedev Physical Institute of the Russian Academy of Sciences

ORCID: 0000-0002-2964-5430

Kudrin K.G.

Lebedev Physical Institute of the Russian Academy of Sciences;
Sechenov First Moscow State Medical University

ORCID: 0000-0001-7041-4557

Received:

30.05.2024

Accepted:

23.01.2025

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References:

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