Pathogenetic approach in the treatment of inflammatory diseases of the nose and paranasal sinuses

Gurov A.V.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology;
Pirogov Russian National Research Medical University

ORCID: 0000-0001-9811-8397

Muzhichkova A.V.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology;
Pirogov Russian National Research Medical University

ORCID: 0000-0001-5940-9343

Yushkina M.A.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology;
Pirogov Russian National Research Medical University

ORCID: 0000-0002-9823-1047

Pathogenetic approach in the treatment of inflammatory diseases of the nose and paranasal sinuses

Authors:

Gurov A.V., Muzhichkova A.V., Yushkina M.A.

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Journal: Russian Bulletin of Otorhinolaryngology. 2023;88(5): 91‑96

DOI: 10.17116/otorino20238805191

Downloaded: 15

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To cite this article:

Gurov AV, Muzhichkova AV, Yushkina MA. Pathogenetic approach in the treatment of inflammatory diseases of the nose and paranasal sinuses. Russian Bulletin of Otorhinolaryngology. 2023;88(5):91‑96. (In Russ.)
https://doi.org/10.17116/otorino20238805191

Подписка 2025 (Russian Bulletin of Otorhinolaryngology)

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In recent years, inflammatory diseases of the nose and paranasal sinuses have been on the rise. In addition to infectious diseases, in the modern world a large percentage of the population suffers from allergic diseases. The approach to therapy and the choice of a drug should take into account the pathogenesis of the inflammatory reaction in the nasal cavity and paranasal sinuses. By exerting its effect, the drug should reduce hyperemia and swelling of the nasal mucosa, reduce the level of mucus secretion, improve the drainage of the paranasal sinuses, i.e. possess vasoconstrictive and anti-allergic properties. As such a drug, you can use the combined intranasal spray Frinozol, which basically contains cetirizine and phenylephrine. The use of Frinozol in the complex treatment of inflammation of the mucous membrane of the nasal cavity and paranasal sinuses contributes to the rapid and pronounced weakening of the symptoms of the disease, and is also the key to successful therapy.

Keywords:

allergic inflammation

mucous membrane

phenylephrine

cetirizine

allergic rhinitis

rhinosinusitis

Authors:

Gurov A.V.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology;
Pirogov Russian National Research Medical University

ORCID: 0000-0001-9811-8397

Muzhichkova A.V.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology;
Pirogov Russian National Research Medical University

ORCID: 0000-0001-5940-9343

Yushkina M.A.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology;
Pirogov Russian National Research Medical University

ORCID: 0000-0002-9823-1047

Received:

09.10.2023

Accepted:

10.10.2023

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