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Dvorayninova O.Yu.

Federal State Budgetary Institution «Research Institute of Oncology», Russian Academy of Medical Sciences, Tomsk, Russia, 634050

Choynzonov E.L.

Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia;
Siberian State Medical University, Tomsk, Russia

Litvyakov N.V.

Tomsk Research Institute of Oncology, Tomsk, Russia, 634050;
Tomsk National Research University, Tomsk, Russia, 634050

The clinical aspects of HPV-positive cancer of the oral cavity and oropharynx

Authors:

Dvorayninova O.Yu., Choynzonov E.L., Litvyakov N.V.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2016;81(1): 72‑77

DOI: 10.17116/otorino201681172-77

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To cite this article:

Dvorayninova OYu, Choynzonov EL, Litvyakov NV. The clinical aspects of HPV-positive cancer of the oral cavity and oropharynx. Russian Bulletin of Otorhinolaryngology. 2016;81(1):72‑77. (In Russ.)
https://doi.org/10.17116/otorino201681172-77

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This review was designed to focus on the prevalence and the magnitude of infection with human papilloma virus (HPV) among healthy subjects and patients presenting with cancer of the oral cavity and oropharynx. We compare the data on the relative frequency ofHPV-positive and HPV-negative cancer of the oral cavity and oropharynx in different populations, peculiarities of the clinical course of this pathology, and methods of its treatment. Much emphasis is placed on the specific clinical and morphological features of HPV-positive cancer of the oral cavity and oropharynx. The general and relapse-free survival rates are consideredwith special reference to the outcome and prognosis of this disease. The currently accepted approaches to the treatment of HPV-positive cancer of the oral cavity and oropharynxare discussed. It is concluded thatHPV-positive cancer of the oral cavity and oropharynx should be regarded as an autonomous pathological condition requiring specific approaches to its management, such as the application of adequate treatment schemes and algorithms.

Keywords:

HPV-infection
cancer of the oral cavity and oropharynx
prognosis
survivorship
therapy

Authors:

Dvorayninova O.Yu.

Federal State Budgetary Institution «Research Institute of Oncology», Russian Academy of Medical Sciences, Tomsk, Russia, 634050

Choynzonov E.L.

Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia;
Siberian State Medical University, Tomsk, Russia

Litvyakov N.V.

Tomsk Research Institute of Oncology, Tomsk, Russia, 634050;
Tomsk National Research University, Tomsk, Russia, 634050

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