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Stulova A.N.

Lomonosov Moscow State University

Semenova N.S.

Lomonosov Moscow State University

Akopyan V.S.

Lomonosov Moscow State University

Terminology of quantitative optical coherence tomography angiography metrics

Authors:

Stulova A.N., Semenova N.S., Akopyan V.S.

More about the authors

Journal: Russian Annals of Ophthalmology. 2024;140(3): 117‑124

DOI: 10.17116/oftalma2024140031117

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To cite this article:

Stulova AN, Semenova NS, Akopyan VS. Terminology of quantitative optical coherence tomography angiography metrics. Russian Annals of Ophthalmology. 2024;140(3):117‑124. (In Russ.)
https://doi.org/10.17116/oftalma2024140031117

Подписка 2025 (Russian Annals of Ophthalmology)
 
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This review is devoted to the English- and Russian-language terminology of quantitative metrics that are used in the evaluation of images obtained by optical coherence tomography angiography (OCT-A). The paper presents an analysis of the use of terms characterizing intraretinal blood flow (vascular density, perfusion density, skeletonized density, etc.), area and shape of the foveal avascular zone, and choriocapillaris blood flow. The factors causing the heterogeneity of OCT-A terminology are described, including the lack of a unified international nomenclature for OCT-A, features of their Russian translation, inconsistency of the parameters in optical coherence tomography systems of different manufacturers. The article also considers ways to standardize the terminology.

Keywords:

optical coherence tomography angiography
vessel density
perfusion density
foveal avascular zone area
circularity index
acircularity index

Authors:

Stulova A.N.

Lomonosov Moscow State University

Semenova N.S.

Lomonosov Moscow State University

Akopyan V.S.

Lomonosov Moscow State University

Received:

03.11.2023

Accepted:

13.12.2023

List of references:

  1. Kashani A, Chen C, Gahm J, Zheng F, Richter G, Philip J. Optical coherence tomography angiography: A comprehensive review of current methods and clinical applications. Prog Retin Eye Res. 2018;60:66-100.  https://doi.org/10.1016/j.preteyeres.2017.07.002
  2. Kalra G, Zarranz-Ventura J, Chahal R, Bernal-Morales C. Optical coherence tomography (OCT) angiolytics: a review of OCT angiography quantitative biomarkers. Surv Ophthalmol. 2022;67(4):1118-1134. https://doi.org/10.1016/j.survophthal.2021.11.002
  3. Sampson D, Dubis A, Chen F, Zawadzki R, Sampson D. Towards standardizing retinal optical coherence tomography angiography: a review. Light Sci Appl. 2022;11(1):63.  https://doi.org/10.1038/s41377-022-00740-9
  4. Fawzi AA. Consensus on Optical Coherence Tomographic Angiography Nomenclature: Do We Need to Develop and Learn a New Language? JAMA Ophthalmol. 2017;135(4):377-378.  https://doi.org/10.1001/jamaophthalmol.2017.0149
  5. Pramil V, Levine ES, Waheed N. Macular Vessel Density in Diabetic Retinopathy Patients : How Can We Accurately Measure and What Can It Tell Us ? Clin Ophthalmol. 2021;15:1517-1527. https://doi.org/10.2147/OPTH.S272328
  6. Fursova AZh, Gamza YuA, Derbeneva AS, Vasil’eva MA. Impact of antiangiogenic therapy on the hemodynamics of the optic nerve and macula in patients with diabetic macular edema and glaucoma. Vestnik Nacional’nogo mediko-hirurgicheskogo Centra im. N.I. Pirogova. 2021;16(1):93-98. (In Russ.). https://doi.org/10.25881/BPNMSC.2021.33.54.016
  7. Fursova AZh, Derbeneva AS, Vasilyeva MA, Tarasov MS, Nikulich IF, Gamza YuA. Structural and microvascular changes in the retina and choroid in patients with chronic kidney disease. Russian Annals of Ophthalmology = Vestnik oftal’mologii. 2021;137(6):99-108. (In Russ.). https://doi.org/10.17116/oftalma202113706199
  8. Fayzrakhmanov RR, Sukhanova AV, Shishkin MM, Krupina EA, Pavlovsky OA, Larina EA, Karpov GO. Changes in perfusional and morphological parameters of the macular area after silicone oil tamponade of the vitreous cavity. Russian Annals of Ophthalmology = Vestnik oftal’mologii. 2020; 136(5):46-51. (In Russ.). https://doi.org/10.17116/oftalma202013605146
  9. Aznabaev BM, Dibaev TI, Ismagilov TN. The analysis of microcirculation parameters of the macular area after ultrasonic vitrectomy using optical coherence tomography-angiography. Saratov Journal of Medical Scientific Research = Saratovskiy nauchno-meditsinskiy zhurnal. 2018;14(4):856-862. (In Russ.).
  10. Stulova AN, Semenova NS, Zheleznyakova AV, Akopyan VS, Lipatov DV, Shestakova MV. Early functional and microcirculatory changes in patients with type 1 diabetes mellitus and no apparent diabetic retinopathy. Diabetes Mellitus = Sakharnyy diabet. 2021;24(3):243-250. (In Russ.). https://doi.org/10.14341/DM12532
  11. Myakoshina EB, Saakyan SV. Characteristics of visual functions and their correlation with OCT-angiography of the macula in patients with small choroidal melanoma. Russian Journal of Clinical Ophthalmology = Klinicheskaya oftal’mologiya. 2022;22(4):216-223. (In Russ.). https://doi.org/10.32364/2311-7729-2022-22-4-216-223
  12. Eskina EN, Belogurova AV, Zinina VS, Gvetadze AA, Smirnova-Sotmari VB. Evaluation of Blood Flow Parameters of the Macular Area and Optic Disc in Patients with Combination of Glaucoma and Axial Myopia. Ophthalmology in Russia = Oftal’mologiya. 2022;19(3):638-646. (In Russ.). https://doi.org/10.18008/1816-5095-2022-3-638-646
  13. Kukharskaya YuI, Volodin PL, Ivanova EV. Optical coherence tomography in angiography mode in the diagnosis of macular edema due to the branch retinal vein occlusion. Bashkortostan Medical Journal = Meditsinskiy vestnik Bashkortostana. 2021;16(1):12-16. (In Russ.).
  14. Sheremet NL, Shmelkova MS, Andreeva NA, Zhorzholadze NV, Fomin AV, Krylova TD, Tsygankova PG. Characteristics of changes in retinal and optic nerve microvascularisature in Leber hereditary optic neuropathy patients seen with optical coherence tomography angiography. Russian Annals of Ophthalmology = Vestnik oftal’mologii. 2020;136(4):171-182. (In Russ., In Engl.) https://doi.org/10.17116/oftalma2020136042171
  15. Kurysheva NI, Sharova GA. Comparative study of retinal microcirculation in primary angle closure disease and early primary open-angle glaucoma. Russian Annals of Ophthalmology = Vestnik oftal’mologii. 2022;138(1):44-51. (In Russ.). https://doi.org/10.17116/oftalma202213801144
  16. Moshetova LK, Vorobyeva IV, Dgebuadze A, Ostroumova OD., Arablinskii AV. Ophthalmological monitoring in patients with hypertension and coronary heart disease. Russian Journal of Clinical Ophthalmology = Klinicheskaya oftal’mologiya. 2021;21(2):51-57. (In Russ.). https://doi.org/10.32364/2311-7729-2021-21-2-51-57.
  17. Safonenko AYu, Ioyleva EE, Gavrilova NA, Vasiliev SG, Andrusyakova EP. Results of dynamic observation of a patient with non-arteritic anterior ischemic optic neuropathy (a clinical case). Bashkortostan Medical Journal = Meditsinskiy vestnik Bashkortostana. 2020;15(4):34-37. (In Russ.).
  18. Levchenko OV, Gavrilova NA, Grigoryev AYu, Kalandari AA, Ioyleva EE, Gadzhieva NS, Kutrovskaya NYu, Tishchenko OE, Kuzmina AV, Zinovyeva AV. Optical coherence tomography and optical coherence tomography-angiography in the diagnosis of chiasmo-sellar region compression. Russian Annals of Ophthalmology = Vestnik oftal’mologii. 2020;136(5):14-22. (In Russ., In Engl.). https://doi.org/10.17116/oftalma202013605114
  19. Kamenskikh TG, Kolbenev IO, Melnikova YA, Andreychenko OA. Optical Coherence Tomography with Angiography in the Analysis of Vitrectomy Effectiveness in Patients with Vitreomacular Traction Syndrome. Ophthalmology in Russia = Oftal’mologiya. 2020;17(1):70-75. (In Russ.). https://doi.org/10.18008/1816-5095-2020-1-70-75
  20. Ma J, Tsviatkou VY., Kanapelka VK. Two-step skeletization of binary images based on the Zhang-Suen model and the producing mask. System Analysis and Applied Information Science = Sistemnyy analiz i prikladnaya informatika. 2021;(1):62-69. (In Russ.). https://doi.org/10.21122/2309-4923-2021-1-62-69
  21. Sheludchenko VM, Kozlovskaya NL, Budzinskaya MV, Krasnolutskaya EI, Durzhinskaya MH, Smirnova TV, Bondarenko TV. The role of optical coherence tomography angiography in the assessment of retinal microcirculation in thrombotic microangiopathy associated with malignant arterial hypertension. Russian Annals of Ophthalmology = Vestnik oftal’mologii. 2022; 138(5-2):177-185. (In Russ.). https://doi.org/10.17116/oftalma2022138052177
  22. Yusef YuN, Semitko SP, Durzhinskaya MH, Kazaryan EE, Sargsyan AZ, Sandodze TS, Ioseliani DG, Budzinskaya MV. Ocular microcirculation after revascularization of the internal carotid artery in the early postoperative period. Russian Annals of Ophthalmology = Vestnik oftal’mologii. 2022; 138(5-2):186-195. (In Russ.). https://doi.org/10.17116/oftalma2022138052186
  23. Dorofeev DA, Kirilik EV, Klimova AV. The effect of retinoprotective therapy on OCT angiography (pilot study). Russian Annals of Ophthalmology = Vestnik oftal’mologii. 2021;137(1):59-66. (In Russ.). https://doi.org/10.17116/oftalma202113701160
  24. Glazko NG, Egorov AE. OCT-A monitoring of the efficacy of neuroprotective therapy for glaucomatous optic neuropathy. Russian Journal of Clinical Ophthalmology = Klinicheskaya oftal’mologiya. 2020;20(1):2-7. (In Russ.). https://doi.org/10.32364/2311-7729-2020-20-1-2-7
  25. Bronskiy DI, Zhukova SI, Zaika VA, Shchuko AG. Assessment of the degree of restoration of the retinal structure and chorioretinal blood flow after surgical treatment of large-diameter macular holes. Acta Biomedica Scientifica. 2021;6(6-1):159-167. (In Russ.). https://doi.org/10.29413/ABS.2021-6.6-1.19
  26. Neroev VV, Okhotsimskaya TD, Fadeeva VA. An account of retinal microvascular changes in diabetes acquired by OCT-angiography. Russian Ophthalmological Journal = Rossiyskiy oftal’mologicheskiy zhurnal. 2017;10(2):40-45. (In Russ.). https://doi.org/10.21516/2072-0076-2017-10-2-40-45
  27. Tultseva SN, Astakhov YS, Rukhovets AG, Titarenko AI. Diagnostic value of OCT-angiography and regional hemodynamic assessment in patients with retinal vein occlusion. Ophthalmology Reports = Oftal’mologicheskiye vedomosti. 2017;10(2):40-48. (In Russ.). https://doi.org/10.17816/OV10240-48
  28. Burnasheva MA, Kulikov AN, Maltsev DS. Personalized analysis of foveal avascular zone with optical coherence tomography angiography. Ophthalmology Reports = Oftal’mologicheskiye vedomosti. 2017;10(4):32-40. (In Russ.). https://doi.org/10.17816/OV10432-40
  29. Shpak AA, Morina NA, Pismenskaya VA. Area of the foveal avascular zone in patients with refractive errors. Russian Annals of Ophthalmology = Vestnik oftal’mologii. 2022;138(6):26-31. (In Russ.). https://doi.org/10.17116/oftalma202213806126
  30. Shkvorchenko DO, Krupina EA, Kakunina SA, Hurdaeva AG. Ocenka izmenenij foveal’noj avaskulyarnoj zony posle uspeshnoj hirurgii otslojki setchatki. Tavricheskij mediko-biologicheskij vestnik. 2019;22(3):74-77. (In Russ.).
  31. Glazko NG, Egorov AE. Analysis of central retinal microcirculation in glaucoma after neuroretinoprotective treatment. Russian Journal of Clinical Ophthalmology = Klinicheskaya oftal’mologiya. 2021;21(1):3-8. (In Russ.). https://doi.org/10.32364/2311-7729-2021-21-1-3-8
  32. Zolnikova IV, Levina DV, Okhotsimskaya TD, Fadeeva VA, Egorova IV, Rogatina EV, Eremeeva EA, Demenkova ON, Rogova SYu. Electroretinography and OCT angiography of the retina and optic nerve in retinitis pigmentosa. Russian Ophthalmological Journal = Rossiyskiy oftal’mologicheskiy zhurnal. 2017;10(3):22-28. (In Russ.). https://doi.org/10.21516/2072-0076-2017-10-3-22-28
  33. Provis JM. Development of the primate retinal vasculature. Prog Retin Eye Res. 2001;20(6):799-821.  https://doi.org/10.1016/s1350-9462(01)00012-x
  34. Anvari P, Najafi A, Mirshahi R, Sardarinia M. Superficial and deep foveal avascular zone area measurement in healthy subjects using two different spectral domain optical coherence tomography angiography devices. J Ophthalmic Vis Res. 2020;15(4):517-523.  https://doi.org/10.18502/jovr.v15i4.7791
  35. Buffolino NJ, Vu AF, De Niear M, Park SS. Factors affecting repeatability of foveal avascular zone measurement using optical coherence tomography angiography in pathologic eyes. Clin Ophthalmol. 2020;14:1025-1033. https://doi.org/10.2147/OPTH.S247172
  36. Shiihara H, Terasaki H, Sonoda S, Kakiuchi N, Sakamoto T. Evaluation of shape of foveal avascular zone by optical coherence tomography angiography in eyes with branch retinal vein occlusion. J Vitreoretin Dis. 2018;2(3): 138-145.  https://doi.org/10.1177/24741264187649
  37. Ersoz M, Hocaoglu M, Muslubas I, Arf S, Karacorlu M. Quantitative assessment of the foveal avascular zone using optical coherence tomography angiography before and after surgery for idiopathic epiretinal membrane. Retina. 2021;41(1):54-59.  https://doi.org/10.1097/IAE.0000000000002794
  38. Krawitz BD, Mo S, Geyman LS, Agemy SA, Scripsema NK, Garcia PM, et al. Acircularity index and axis ratio of the foveal avascular zone in diabetic eyes and healthy controls measured by optical coherence tomography. Vis Res. 2017;139:177-186.  https://doi.org/10.1016/j.visres.2016.09.019
  39. Chu Z, Zhang Q, Gregori G, Rosenfeld PJ, Wang RK. Guidelines for imaging the choriocapillaris using OCT angiography. Am J Ophthalmol. 2020; 222:92-101.  https://doi.org/10.1016/j.ajo.2020.08.045
  40. Maltsev DS, Fomin AV, Kulikov AN, Vasiliev AS. Evaluation of choriocapillaris with high-speed spectral-domain optical coherence tomography angiography and image averaging. Russian Annals of Ophthalmology = Vestnik oftal’mologii. 2021;137(3):76-84. (In Russ.). https://doi.org/10.17116/oftalma202113703176
  41. Burnasheva MA, Maltsev DS, Kulikov AN. Retinal and choroidal circulation in patients with lattice retinal degeneration: optical coherence tomography-angiography study. Ophthalmology Reports = Oftal’mologicheskiye vedomosti. 2022;15(3):39-45. (In Russ.). https://doi.org/10.17816/OV110752
  42. Stulova AN, Semenova NS, Zheleznyakova AV, Akopyan VS, Lipatov DV. OCTA and Functional Signs of Preclinical Retinopathy in Type 1 Diabetes Mellitus. Ophthalmic Surg Lasers Imaging Retina. 2021;52(S1):S30-S34.  https://doi.org/10.3928/23258160-20210518-06
  43. Pichi F, Salas EC, Smet M De, Gupta V, Zierhut M, Munk MR. Standardisation of optical coherence tomography angiography nomenclature in uveitis: first survey results. Br J Ophthalmol. 2021;105(7):941-947.  https://doi.org/10.1136/bjophthalmol-2020-316881
  44. Aytulun A, Cruz-Herranz A, Aktas O, et al. APOSTEL 2.0 Recommendations for Reporting Quantitative Optical Coherence Tomography Studies. Neurology. 2021;97(2):68-79.  https://doi.org/10.1212/WNL.0000000000012125
  45. Spaide R, Jaffe G, Sarraf D, et al. Consensus Nomenclature for Reporting Neovascular Age-Related Macular Degeneration Data: Consensus on Neovascular Age-Related Macular Degeneration Nomenclature Study Group. Ophthalmology. 2020;127(5):616-636.  https://doi.org/10.1016/j.ophtha.2019.11.004
  46. Munk MR, Kashani AH, Tadayoni R, et al. Recommendations for OCT Angiography Reporting in Retinal Vascular Disease: A Delphi Approach by International Experts. Ophthalmol Retin. 2022;6(9):753-761. 
  47. Mendonça L, Perrott-Reynolds R, Schwartz R, et al. Deliberations of an International Panel of Experts on OCT Angiography Nomenclature of Neovascular Age-Related Macular Degeneration. Ophthalmology. 2021;128(7): 1109-1112. https://doi.org/10.1016/j.ophtha.2020.12.022
  48. Humphrey-Murto S, Varpio L, Wood TJ, Gonsalves C, Ufholz LA, Mascioli K, Wang C, Foth T. The Use of the Delphi and Other Consensus Group Methods in Medical Education Research: A Review. Acad Med. 2017;92(10): 1491-1498. https://doi.org/10.1097/ACM.0000000000001812

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