Precorneal tear film after corneal collagen cross-linking in keratoconus (preliminary report)

Voronin G.V.

Research Institute of Eye Diseases

SPIN RSCI: 4300-0648
Scopus AuthorID: 7005174792
ResearcherID: AAO-7850-2021
ORCID: 0000-0002-5769-6593

Bubnova I.A.

Research Institute of Eye Diseases

Averich V.V.

Krasnov Research Institute of Eye Diseases

ORCID: 0000-0001-5778-4123

Sarkisova K.G.

Research Institute of Eye Diseases

Precorneal tear film after corneal collagen cross-linking in keratoconus (preliminary report)

Authors:

Voronin G.V., Bubnova I.A., Averich V.V., Sarkisova K.G.

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Journal: Russian Annals of Ophthalmology. 2021;137(5‑2): 224‑230

DOI: 10.17116/oftalma2021137052224

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To cite this article:

Voronin GV, Bubnova IA, Averich VV, Sarkisova KG. Precorneal tear film after corneal collagen cross-linking in keratoconus (preliminary report). Russian Annals of Ophthalmology. 2021;137(5‑2):224‑230. (In Russ.)
https://doi.org/10.17116/oftalma2021137052224

Подписка 2025-2 (Russian Annals of Ophthalmology)

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PURPOSE

To study the condition of precorneal tear film in keratoconus patients after corneal collagen cross-linking (CXL).

MATERIAL AND METHODS

The study enrolled 24 patients (30 eyes) with stages I—III progressive keratoconus. All study patients underwent standard (Dresden) protocol CXL. Patients were examined before the surgery and 1 week, 1 month, and 3 months postoperatively. The condition of precorneal tear film was evaluated based on the results of Norn test (the tear film break-up time), Schirmer test, Jones test, optical coherence tomography based lacrimal meniscometry, and improved tearscopy.

RESULTS

One month after CXL, patients with keratoconus experienced transient changes in the precorneal tear film condition — the tear film break-up time was reduced, the tear secretion was elevated, the lacrimal meniscus biometry parameters were increased, and the thickness of the tear film lipid layer was decreased.

CONCLUSION

Corneal changes resulting from CXL lead to transient disorders of the mucin and lipid layers of the precorneal tear film, which requires adequate tear substitute therapy in the postoperative period.

Keywords:

keratoconus

cross-linking

dry eye

tear film

Authors:

Voronin G.V.

Research Institute of Eye Diseases

SPIN RSCI: 4300-0648
Scopus AuthorID: 7005174792
ResearcherID: AAO-7850-2021
ORCID: 0000-0002-5769-6593

Bubnova I.A.

Research Institute of Eye Diseases

Averich V.V.

Krasnov Research Institute of Eye Diseases

ORCID: 0000-0001-5778-4123

Sarkisova K.G.

Research Institute of Eye Diseases

Received:

03.12.2020

Accepted:

15.03.2021

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