Tarsorrhaphy in rehabilitation of patients with thyroid eye disease

Grusha Y.O.; Ismailova D.S.; Fettser E.I.

doi:https://doi.org/10.17116/oftalma202113705147

Grusha Y.O.

I.M. Sechenov First Moscow State Medical University (Sechenov University);
Krasnov Research Institute of Eye Diseases

ORCID: 0000-0002-6461-8243

Ismailova D.S.

Research Institute of Eye Diseases

Fettser E.I.

Krasnov Research Institute of Eye Diseases;
Sechenov First Moscow State Medical University

ORCID: 0000-0002-3729-7480

Tarsorrhaphy in rehabilitation of patients with thyroid eye disease

Authors:

Grusha Y.O., Ismailova D.S., Fettser E.I.

More about the authors

Journal: Russian Annals of Ophthalmology. 2021;137(5): 47‑51

DOI: 10.17116/oftalma202113705147

Read: 4711 times

To cite this article:

Grusha YO, Ismailova DS, Fettser EI. Tarsorrhaphy in rehabilitation of patients with thyroid eye disease. Russian Annals of Ophthalmology. 2021;137(5):47‑51. (In Russ., In Engl.)
https://doi.org/10.17116/oftalma202113705147

Подписка 2026 Вестник офтальмологии (Russian Annals of Ophthalmology)

Использование инфографики авторами научных работ

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PURPOSE

To evaluate the role of tarsorrhaphy and its effectiveness in the treatment of patients with thyroid eye disease (TED).

MATERIAL AND METHODS

The study identified the patients who required tarsorrhaphy for corneal lesions associated with TED among the total number of 457 patients who underwent tarsorrhaphy at the Research Institute of Eye Diseases over the past 20 years.

RESULTS

Overall, 477 tarsorrhaphy surgeries (457 patients) were performed, including temporary and permanent, partial and complete. The corneal involvement in TED was the indication for tarsorrhaphy in 81 patients (101 tarsorrhaphies). TED patients were divided depending on the date of operation, and it was found that 61 tarsorrhaphies were performed in the period from 2000 to 2009, and 40 similar interventions were performed in the period from 2010 to 2019.

CONCLUSION

The reduction in the number of tarsorrhaphy surgeries in patients with TED in the last decade due to improvement of techniques for bony decompression of the orbit and increase in the number of these operations allowed significant reduction of the degree of proptosis and, as a consequence, the exposure surface area of the eye. However, despite all the successes achieved in orbital surgery, tarsorrhaphy still remains an affordable technique that can always be used in case of corneal lesions in thyroid eye disease.

Keywords:

tarsorrhaphy

thyroid eye disease

keratopathy

lagophthalmos

corneal ulcer

exophthalmos

bony orbital decompression

neurotrophic keratitis

Authors:

Grusha Y.O.

I.M. Sechenov First Moscow State Medical University (Sechenov University);
Krasnov Research Institute of Eye Diseases

ORCID: 0000-0002-6461-8243

Ismailova D.S.

Research Institute of Eye Diseases

Fettser E.I.

Krasnov Research Institute of Eye Diseases;
Sechenov First Moscow State Medical University

ORCID: 0000-0002-3729-7480

Received:

30.12.2020

Accepted:

07.07.2021

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References:

Stewart WB, ed. Surgery of the eyelid, orbit and lacrimal system. Vol. 1—2. Ophthalmology monographs (Is. 8). San Francisco: American Academy of Ophthalmology; 1994.
Holland EJ, ed. Cornea. Vol 3. St. Louis: Mosby; 1997;1815-1832.
Cosar CB, Cohen EJ, Rapuano CJ, et al. Tarsorrhaphy: clinical experience from a cornea practice. Cornea. 2001;20(8):787-791. https://doi.org/10.1097/00003226-200111000-00002
Bouchard CS. Lateral tarsorrhaphy for a noncompliant patient with floppy eyelid syndrome. Am J Ophthalmol. 1992;114:367-368. https://doi.org/10.1016/s0002-9394(14)71808-2
Rosenberg GJ. Temporary tarsorrhaphy suture to prevent or treat scleral show and ectropion secondary to laser resurfacing or laser blepharoplasty. Plast Reconstr Surg. 2000;106:721-725.
Pakarinen M, Tervo T, Tarkkanen A. Tarsorraphy in the treatment of persistent corneal lesions. Acta Ophthalmol Suppl. 1987;182:69-73. https://doi.org/10.1111/j.1755-3768.1987.tb02595.x
Luo QL, Tang L, He WM, et al. Clinical investigation of tarsorrhaphy suture for treatment thyroid-associated ophthalmopathy. Zhonghua Yan Ke Za Shi. 2005;41(9):777-780.
Grusha YaO, Kasparov AA, Ismailova DS, Stoiukhina AS, Merzliakova OYu. Complex treatment for decompensated edematous exophthalmos. Vestnik oftal’mologii. 2009;125(3):46-50 (In Russ.).
Lekskul M, Fracht HU, Cohen EJ, et al. Nontraumatic corneal perforation. Cornea. 2000;19:313-319. https://doi.org/10.1097/00003226-200005000-00011
Grusha YO, Ismailova DS, Gankovskaia OA. Risk factors of corneal damage in patients with Thyroid Eye Disease. Vestnik oftal’mologii. 2010;126(6): 35-38. (In Russ.).
Avetisov SE, Grusha YO, Ismailova DS, Kochetkov PA, Danilov SS, Sviridenko NYu. Surgical rehabilitation of patients with thyroid eye disease: Systematic approach. Vestnik oftal’mologii. 2017;133(1):4-10. (In Russ.). https://doi.org/10.1111/j.10.17116/oftalma201713314-10
Nowak M, Marek B, Kos-Kudła B, Kajdaniuk D, Siemińska L. Tear film profile in patients with active thyroid orbithopathy. Klin Oczna. 2005;107: 479-482.
Gilbard JP, Farris RL. Ocular surface drying and ocular tear film osmolarity in thyroid eye disease. Acta Ophthalmol (Copenh). 1983;61:108-116. https://doi.org/10.1111/j.1755-3768.1983.tb01401.x
Eckstein AK, Finkenrath A, Heiligenhaus A, Renzing-Koehler K Esser J, Krüger C, Quadbeck B, Steuhl KP, Gieseler RK. Dry eye syndrome in thyroid-associated ophthalmopathy: lacrimal expression of TSH receptor-specific autoantibodies. Acta Ophthalmol Scand. 2004;82:291-297. https://doi.org/10.1111/j.1395-3907.2004.00268.x
Brasil MV, Brasil OF, Vieira RP, Vaisman M, Amaral Filho OM. Tear film analysis and its relation with palpebral fissure height and exophthalmos in Graves’ ophthalmopathy. Arq Bras Oftalmol. 2005;68(5):615-618. https://doi.org/10.1590/s0004-27492005000500007
Khalil HA, De Keizer RJ, Kiljstra A. Secretory IgA and Lysozyme in tears of patients with Graves’ ophthalmopathy. Doc Ophthalmol. 1989;72:329-334. https://doi.org/10.1007/BF00153500
Grusha YO, Fedorov AA, Ivanchenko YuF. Experimental assessment of various external tarsorrhaphy technique. Vestnik oftal’mologii. 2010;126(3):15-18. (In Russ.).
Gossman MD, Bowe BE, Tanenbaum M. Reversible suture tarsorrhaphy for eyelid malposition and keratopathy. Ophthalm Surg. 1991;22:237-239.
Choi JC, Lucarelli MJ, Shore JW. Use of botulinum A toxin in patients at risk for wound complications following eyelid reconstruction. Ophthalm Plast Reconstr Surg. 2000;13:259-264. https://doi.org/10.1097/00002341-199712000-00006
Perusse P. Localized distichiasis after tarsorrhaphy. Am J Ophthalmol. 1992; 114:104-105. https://doi.org/10.1016/s0002-9394(14)77425-2
Glatt HJ. Management of unsuccessful tarsorrhaphy separation with polytetrafluoroethylene (Gor-Tex) stent. Am J Ophthalmol. 1993;115:264-265. https://doi.org/10.1016/s0002-9394(14)73941-8
Korn E. Tarsorrhaphy: a laser-assisted approach. Ann Ophthalmol. 1990;22: 154-157.