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Panova I.E.

St. Petersburg branch of S.N. Fyodorov National Medical Research Center «MNTK «Eye Microsurgery»

Samkovich E.V.

Saint Petersburg branch of S.N. Fyodorov National Medical Research Center «MNTK «Eye Microsurgery»

Melikhova M.V.

Saint Petersburg branch of S.N. Fyodorov National Medical Research Center «MNTK «Eye Microsurgery»

Grigoreva N.N.

N.N. Burdenko National Medical Research Center of Neurosurgery

Indocyanine green angiography in the diagnostics of choroidal tumors

Authors:

Panova I.E., Samkovich E.V., Melikhova M.V., Grigoreva N.N.

More about the authors

Journal: Russian Annals of Ophthalmology. 2020;136(5): 5‑13

DOI: 10.17116/oftalma20201360515

Read: 2951 times

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Table of contents

INDOCYANINE GREEN ANGIOGRAPHY IN THE DIAGNOSTICS OF CHOROIDAL TUMORS
INDOCYANINE GREEN ANGIOGRAPHY IN THE DIAGNOSTICS OF CHOROIDAL TUMORS

To cite this article:

Panova IE, Samkovich EV, Melikhova MV, Grigoreva NN. Indocyanine green angiography in the diagnostics of choroidal tumors. Russian Annals of Ophthalmology. 2020;136(5):5‑13. (In Russ.)
https://doi.org/10.17116/oftalma20201360515

Подписка 2026 Вестник офтальмологии (Russian Annals of Ophthalmology)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

PURPOSE

To study the use of ultrasound color Doppler imaging and indocyanine green (ICG) angiography for identification of malignant vasculature of choroidal tumors.

MATERIAL AND METHODS

The study included 46 patients (46 eyes) with tumors of the choroid: 19 men and 26 women aged 22 to 89 years, average age 53.2±17.1 years. All patients underwent indocyanine green angiography and Doppler ultrasound imaging. At the time of examination, thickness of the tumors ranged from 1.1 mm to 3.0 mm, and the base diameter from 4.0 mm to 13.0 mm. Choroidal melanoma was diagnosed in 27 patients, choroidal nevus in 10, choroidal hemangioma in 5, and choroidal metastasis in 4 patients.

RESULTS

The results of indocyanine green angiography demonstrate that the pathological malignant vasculature was determined: nevi was diagnosed in 7 out of 10 patients, choroidal melanoma in 16 out of 27, metastasis in 2 out of 4, and hemangioma in none of the 5 patients. Pathological malignant vasculature was determined in most patients with choroidal melanoma (77.8%), in all patients with choroidal hemangioma and in 3 patients with choroidal metastases. Ultrasound imaging revealed malignant vasculature in 15 of 27 (56%) patients with choroidal melanoma, it could be identified in all patients with hemangioma in 2 patients and with choroidal metastases, and in none patients with choroidal nevi.

CONCLUSIONS

Indocyanine green angiography helps verify malignant vasculature in 77.8% of patients with small and medium sized choroidal melanomas. Angioarchitecture of choroidal tumors visualized with indocyanine green angiography is characterized by variability of patterns, which should be taken into account in the differential diagnosis of various pathological diseases.

Keywords:

indocyanine green angiography
choroidal tumors
choroidal melanoma
choroidal nevi
choroidal hemangioma
choroidal metastasis
Doppler ultrasound imaging

Authors:

Panova I.E.

St. Petersburg branch of S.N. Fyodorov National Medical Research Center «MNTK «Eye Microsurgery»

Samkovich E.V.

Saint Petersburg branch of S.N. Fyodorov National Medical Research Center «MNTK «Eye Microsurgery»

Melikhova M.V.

Saint Petersburg branch of S.N. Fyodorov National Medical Research Center «MNTK «Eye Microsurgery»

Grigoreva N.N.

N.N. Burdenko National Medical Research Center of Neurosurgery

Received:

31.10.2019

Accepted:

26.12.2019

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