The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Safonova T.N.

FGBU "NII glaznykh bolezneĭ" RAMN, Moskva

At’kova E.L.

Scientific Research Institute of Eye Diseases, Moscow, Russia

Kintukhina N.P.

Research Institute of Eye Diseases, 11 A, B, Rossolimo St., Moscow, Russian Federation, 119021

Reznikova L.V.

FGBU "NII glaznykh bolezneĭ" RAMN, Moskva

Modern methods of evaluating the morphological and functional state of the eyelids in chronic blepharitis

Authors:

Safonova T.N., At’kova E.L., Kintukhina N.P., Reznikova L.V.

More about the authors

Journal: Russian Annals of Ophthalmology. 2018;134(5): 276‑281

Read: 1521 times


To cite this article:

Safonova TN, At’kova EL, Kintukhina NP, Reznikova LV. Modern methods of evaluating the morphological and functional state of the eyelids in chronic blepharitis. Russian Annals of Ophthalmology. 2018;134(5):276‑281. (In Russ.)
https://doi.org/10.17116/oftalma2018134051276

Recommended articles:

References:

  1. Maichuk YuF, Yani EV. New approaches in the treatment of blepharitis. Kataraktal’naya i refraktsionnaya khirurgiya. 2012;12(1):59-62. (In Russ.)
  2. Prozornaja LP, Brzheskij VV. The effectiveness of physiotherapeutic and hygienic procedures in the treatment of children and adults with chronic blepharitis and the «dry eye» syndrome. Vestnik oftal’mologii. 2013;129(3):68-73. (In Russ.)
  3. Turnbull AM, Mayfield MP. Blepharitis. BMJ. 2012;344:e3328. https://doi.org/10.1136/bmj.e3328
  4. Shokirova MM, Kopayeva VG. Eva- luation of pathogenetic component of lacrimal substitutive therapy in the complex stage-by-stage treatment of posterior blepharitis, associated with demodectic lesions of the eyelid margins. Oftal’mokhirurgiya. 2017;1:78-82. (In Russ.) https://doi.org/10.25276/0235-4160-2017-1-78-82
  5. Mannis MJ, Holland EJ. Ocular Surface Disease: Medical and Surgical Management. New York: Springer-Verlag; 2006. https://doi.org/10.1007/b9728
  6. Safonova TN, Kintyukhina NP, Petrenko AE, Gladkova OV. Prevention of dry eye syndrome in chronic demodex blepharitis. RMZh. Klinicheskaya oftal’mologiya. 2016;16(2):89-93. (In Russ.) https://doi.org/10.21689/2311-7729-2016-16-2-89-93
  7. Duncan K, Jeng BH. Medical management of blepharitis. Cur Opin Ophthalmol. 2015;26(4):289-294.
  8. O’Callaghan RJ. The Pathogenesis of Staphylococcus aureus eye Infections. Pathogens. 2018;7(1):pii: E9. https://doi.org/10.3390/pathogens7010009
  9. Auw-Hädrich C, Reinhard T. Blepharitis component of dry eye syndrome. Ophthalmologe. 2018;115(2):93-99. https://doi.org/10.1007/s00347-017-0606-8
  10. Safonova TN, Kintyukhina NP, Petrenko AE, Gladkova OV. First experience of «Deksodem phyto» use in treating chronic demodex blepharitis. Tochka zrenija. Vostok—Zapad. 2016;1:145-147. (In Russ.)
  11. Ban Y, Ogawa Y, Goto E, Uchino M, Terauchi N, Seki M, Nakaya M, Saiki M, Mori T, Okamoto S, Matsumoto Y, Dogru M, Shimazaki J, Tsubota K. Tear function and lipid layer alterations in dry eye patients with chronic graft-vs-host disease. Eye (Lond). 2009;23(1):202-208. https://doi.org/10.1038/eye.2008.340
  12. Korb DR, Blackie CA. Restoration of meibomian gland functionality with novel thermodynamic treatment device-a case report. Cornea. 2010;29(8):930-933. https://doi.org/10.1097/ICO.0b013e3181ca36d6
  13. Korb DR, Blackie CA, Finnemore VM, Douglass T. Effect of using a combination of lid wipes, eye drops, and omega-3 supplements on meibomian gland functionality in patients with lipid deficient/evaporative dry eye. Cornea. 2015;34(4):407-412. https://doi.org/10.1097/ICO.0000000000000366
  14. Safonova TN, Zabegailo AO, Makarov IA. Sposob opredeleniya stepeni blefarokon’yunktival’noi formy sindroma sukhogo glaza [A method for determining the degree of blepharoconjunctival form of dry eye syndrome]. Patent RF №2500340, priority 22.11.12.
  15. Zabegailo AO, Safonova TN, Makarov IA. A new way to determine the degree of severity of the «dry eye» syndrome. Kataraktal’naya i refraktsionnaya khirurgiya. 2013;13(1):35-38. (In Russ.)
  16. Kintyukhina NP, Safonova TN, Gladkova OV. The use of laser scanning confocal microscopy of eyelids during intraprototic probing of meibomian glands. Sovremennye tekhnologii v oftal’mologii. 2017;4:112-114. (In Russ.)
  17. Avetisov SE, Fedorov AA, Polunin GS, Pimenidi MK. Sposob opredeleniya funktsional’nogo sostoyaniya meibomievykh zhelez [A method for determining the functional state of meibomian glands]. Pa- tent RF №2373832, priority 11.07.08.
  18. Safonova TN, Vasil’ev VI, Lihvanceva VG. Sindrom Shegrena. M.: Izdatel’stvo Moskovskogo Universiteta; 2013. (In Russ.)
  19. Trubilin VN, Polunina EG, Alieva AE, Kurenkov VV, Zhemchugova AV, Kurenkova SV. Sposob otsenki morfofunktsional’nogo sostoyaniya meibomievykh zhelez — biometriya meibomievykh zhelez [A method for evaluating the morphofunctional state of meibomian glands — the meibomian gland biometry]. Patent RF №2567829, priority 22.10.14.
  20. Trubilin VN, Polunina EG, Markova EYu, Andzhelova DV, Kurenkova SV, Bezmel’nitsyna LYu. Methods of Screening for Meibomian Gland Dysfunction. Oftal’mologiya. 2016;13(4):235-240. (In Russ.)
  21. Trubilin VN, Polunina EG, Alieva AE, Kurenkov VV, Zhemchugova AV. A novel method of complex evaluation of meibomian glands morphological and functional state. Oftal’mologiya. 2014;11(2):39-46. (In Russ.)
  22. Yeo S, Tan JH, Acharya UR, Sudarshan VK, Tong L. Longitudinal Changes in Tear Evaporation Rates After Eyelid Warming Therapies in Meibomian Gland Dysfunction. Invest Ophthalmol Vis Sci. 2016;57(4):1974-1981. https://doi.org/10.1167/iovs.16-19088
  23. Su TY, Ho WT, Chiang SC, Lu CY, Chiang HK, Chang SW.J Infrared thermography in the evaluation of meibomian gland dysfunction. J Formos Med Assoc. 2017;116(7):554-559. https://doi.org/10.1016/j.jfma.2016.09.012
  24. Arita R, Shirakawa R, Maeda S, Yamaguchi M, Ohashi Y, Amano S. Decreased surface temperature of tarsal conjunctiva in patients with meibomian gland dysfunction. JAMA Ophthalmol. 2013;131(6):818-819. https://doi.org/10.1001/jamaophthalmol.2013.1895
  25. Kawali AA. Thermography in ocular inflammation. Indian J Radiol Imaging. 2013;3:23:281-283.
  26. Avetisov SE, Novikov IA, Lucevich EJe, Rejn ES. Use of infrared thermography in ophthalmology. Vestnik oftal’mologii. 2017;133(6):99-105. (In Russ.) https://doi.org/10.17116/oftalma2017133699-104
  27. Nelson JD, Shimazaki J, Benitez-del-Castillo JM, Craig JP, McCulley JP, Den S, et al. The International Workshop on Meibomian Gland Dysfunction: Report of the Definition and Classification Subcommittee. Invest Ophthalmol Vis Sci. 2011;52(4):1930-1937. https://doi.org/10.1167/iovs.10-6997b
  28. Egorova GB, Mitichkina TS, Fedorov AA, Shamsudinova AR. Topical cyclosporine for the treatment of ocular surface changes in contact lens wearers. Vestnik oftal’mologii. 2015;131(1):36-42. (In Russ.) https://doi.org/10.17116/oftalma2015131136-42
  29. At’kova EL, Yartsev VD, Krakhovetskii NN, Root AO, Rein DA. Use of optical coherence tomography based lacrimal meniscometry in dacryology. Vestnik oftal’mologii. 2016;132(6):101-107. (In Russ.) https://doi.org/10.17116/oftalma20161326101-107
  30. Foulks GN, Pflugfelder SC. New testing options for diagnosing and grading dry eye disease. Am J Ophthalmol. 2014;157(6):1122-1129. https://doi.org/10.1016/j.ajo.2014.03.002
  31. Arita R, Fukuoka S, Morishige N. New insights into the morphology and function of meibomian glands. Exp Eye Res. 2017;163:64-71. https://doi.org/10.1016/j.exer.2017.06.010
  32. Arita R, Fukuoka S, Morishige N. New Insights Into the Lipid Layer of the Tear Film and Meibomian Glands. Eye Contact Lens. 2017;43(6):335-339. https://doi.org/10.1097/ICL.0000000000000369
  33. Geerling G, Baudouin C, Aragona P, Rolando M, Boboridis KG, Benítez-Del-Castillo JM, Akova YA, Merayo-Lloves J, Labetoulle M, Steinhoff M, Messmer EM. Emerging strategies for the diagnosis and treatment of meibomian gland dysfunction: Proceedings of the OCEAN group meeting. Ocul Surf. 2017;15(2):179-192. https://doi.org/10.1016/j.jtos.2017.01.006
  34. Egorova GB, Fedorov AA, Mitichkina TS, Shamsudinova AR, Safonova TN. The effect of tear-replacement and corneoprotective therapy on the condition of the eye surface with the «dry eye» syndrome. RMZh Klinicheskaya Oftal’mologiya. 2015;1:15-21. (In Russ.)
  35. Egorova GB, Novikov IA, Mitichkina TS. Perfection and assessment of the possibilities of the method of tiascopy. Vestnik oftal’mologii. 2011;127(6):35-40. (In Russ.)
  36. Eom Y, Lee JS, Kang SY, Kim HM, Song JS. Correlation between quantitative measurements of tear film lipid layer thickness and meibomian gland loss in patients with obstructive meibomian gland dysfunction and normal controls. Am J Ophthalmol. 2013;155(6):1104-1110.e2. https://doi.org/10.1016/j.ajo.2013.01.008
  37. Matsumoto Y, Sato EA, Ibrahim OM, Dogru M, Tsubota K. The application of in vivo laser confocal microscopy to the diagnosis and evaluation of meibomian gland dysfunction. Mol Vis. 2008;14:1263-1271.
  38. Dong X, Gao Y, Zeng M, Liu M, Li W, Liu Q, Wang B. Analysis of meibum by gas chromatography-mass spectrometry. Zhonghua Yan Ke Za Zhi. 2015;51(9):668-672.
  39. Butovich IA. Meibomian glands, meibum, and meibogenesis. Exp Eye Res. 2017;163:2-16. https://doi.org/10.1016/j.exer.2017.06.020
  40. Knop E, Knop N, Millar T, Obata H, Sullivan DA. The international workshop on meibomian gland dysfunction: report of the subcommittee on anatomy, physiology, and pathophysiology of the meibomian gland. Invest Ophthalmol Vis Sci. 2011;52(4):1938-1978. https://doi.org/10.1167/iovs.10-6997c
  41. Arita R, Mori N, Shirakawa R, Asai K, Imanaka T, Fukano Y, Nakamura M, Amano S. Meibum Color and Free Fatty Acid Composition in Patients With Meibomian Gland Dysfunction. Invest Ophthalmol Vis Sci. 2015;56(8):4403-4412. https://doi.org/10.1167/iovs.14-16254
  42. Joffre C, Souchier M, Leclere L, Buteau B, Grégoire S, Lizard G, Montange T, Acar N, Bron A, Creuzot-Garcher C, Diebold Y, Bretillon L. Branched-chain fatty acids, increased in tears of blepharitis patients, are not toxic for conjunctival cells. Br J Ophthalmol. 2009;93(10):1391-1395.
  43. Yeotikar NS, Zhu H, Markoulli M, Nichols KK, Naduvilath T, Papas EB. Functional and Morphologic Changes of Meibomian Glands in an Asymptomatic Adult Population. Invest Ophthalmol Vis Sci. 2016;57(10):3996-4007. https://doi.org/10.1167/iovs.15-18467
  44. Alsuhaibani AH, Carter KD, Abràmoff MD, Nerad JA. Utility of meibography in the evaluation of meibomian glands morphology in normaland diseased eyelids. Saudi J Ophthalmol. 2011;25(1):61-66. https://doi.org/10.1016/j.sjopt.2010.10.005
  45. AlDarrab A, Alrajeh M, Alsuhaibani AH. Meibography for eyes with posterior blepharitis. Saudi J Ophthalmol. 2017;31(3):131-134. https://doi.org/10.1016/j.sjopt.2017.05.014
  46. Peyman GA, Ingram CP, Montilla LG, Witte RS. A high-resolution 3D ultrasonic system for rapid evaluation of the anterior and posterior segment. Ophthalmic Surg Lasers Imaging. 2012;43(2):143-151. https://doi.org/10.3928/15428877-20120105-01
  47. Trubilin VN, Polunina EG, Kurenkov VM. Possibilities of using ultrasonic biomicroscopy in assessing the condition of the eyelids and conjunctiva. Oftal’mologiya. 2014;11(4):32-40. (In Russ.)
  48. Liang Q, Pan Z, Zhou M, Zhang Y, Wang N, Li B, Baudouin C, Labbé A. Evaluation of optical coherence tomography meibography in patients with obstructive meibomian gland dysfunction. Cornea. 2015;34(10):1193-1199. https://doi.org/10.1097/ICO.0000000000000563
  49. Yoo YS, Na KS, Byun YS, Shin JG, Lee BH, Yoon G, Eom TJ, Joo CK. Examination of gland dropout detected on infrared meibography by using optical coherence tomography meibography. Ocul Surf. 2017;15(1):130-138.e1. https://doi.org/10.1016/j.jtos.2016.10.001
  50. Messmer EM, Torres Suárez E, Mackert MI, Zapp DM, Kampik A. In vivo confocal microscopy in blepharitis. Klin Monbl Augenheilkd. 2005;222(11):894-900.
  51. Fasanella V, Agnifili L, Mastropasqua R, Brescia L, Di Staso F, Ciancaglini M, Mastropasqua L. In vivo Laser scanning confocal microscopy of human meibomian glands in aging and ocular surface diseases. BioMed Research International. 2016;7432131. https://doi.org/10.1155/2016/7432131
  52. Guillon M, Maissa C, Wong S. Eyelid margin modification associated with eyelid hygiene in anterior blepharitis and meibomian gland dysfunction. Eye and Contact Lens. 2012;38(5):319-325. https://doi.org/10.1097/ICL.0b013e318268305a
  53. Safonova TN, Lucevich EE, Kintyukhina NP. Microcirculatory changes in bulbar conjunctiva in various diseases. Vestnik oftal’mologii. 2016;132(2):90-95. (In Russ.) https://doi.org/10.17116/oftalma2016132290-95
  54. Safonova TN, Kintyukhina NP, Sidorov VV, Gladkova OV, Reyn ES. Microcirculatory blood and lymph flow examination in eyelid skin by laser Doppler flowmetry. Vestnik oftal’mologii. 2017;133(3):16-21. (In Russ.) https://doi.org/10.17116/oftalma2017133316-21
  55. Safonova TN, Kintyukhina NP, Sidorov VV, Gladkova OV. Laser doppler flowmetry in assessing the effectiveness of treatment of chronic demodex blefaritis. Rossiiskii oftal’mologi- cheskii zhurnal. 2017;10(2):62-66. (In Russ.)
  56. Filatova IA, Romanova IA. The ability to predict the risk of rejection of free skin graft in the reconstruction of the eyelids. Rossiiskii oftal’mologicheskii zhurnal. 2011;4(4):81-85. (In Russ.)

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.